Coletyl Uses

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What is Coletyl?

Contracting the pupil during and immediately following surgery. It is also reduces eye pressure in the first 24 hours after cataract surgery.

Coletyl ocular is a cholinergic agent/miotic. The exact way Coletyl ocular works is not fully understood. It works by constricting the iris and other parts of the eye, resulting in reduction of eye pressure.

Coletyl indications

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Coletyl ophthalmic reduces the pressure in the eye by increasing the amount of fluid that drains from the eye. Coletyl ophthalmic also causes the pupil to become smaller and reduces its response to light or dark conditions.

Coletyl ophthalmic is used to treat glaucoma by lowering the pressure inside the eye.

Coletyl ophthalmic may also be used for purposes other than those listed in this medication guide.

How should I use Coletyl?

Use Isopto Coletyl drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Isopto Coletyl drops.

Coletyl description

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An antifungal antibiotic. Coletyl may be given by mouth in the treatment of tinea infections.

Coletyl dosage

Usual Adult Dose for Intraocular Hypertension

Instill no more than 0.5 mL into the anterior chamber of the affected eye(s) for the production of miosis during ocular surgery.

Comments:

-Miosis is usually maximal within 2 to 5 minutes after application.

-This drug may be instilled before or after securing sutures.

Uses:

-To obtain miosis during surgery

-To reduce the intensity of intraocular pressure elevation in the first 24 hours following cataract surgery

Usual Adult Dose for Production of Miosis

Instill no more than 0.5 mL into the anterior chamber of the affected eye(s) for the production of miosis during ocular surgery.

Comments:

-Miosis is usually maximal within 2 to 5 minutes after application.

-This drug may be instilled before or after securing sutures.

Uses:

-To obtain miosis during surgery

-To reduce the intensity of intraocular pressure elevation in the first 24 hours following cataract surgery

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

-The manufacturer product information should be consulted.

-Intraocular solution: For single-dose intraocular use only; discard unused portion

-Ophthalmic solution: For topical use only; not for injection

Coletyl interactions

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What other drugs will affect Coletyl?

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Before using this medication, tell your doctor if you are using another eye medication, especially if it is a nonsteroidal anti-inflammatory drug (NSAID) such as flurbiprofen (Ocufen), suprofen (Profenal), diclofenac (Voltaren), or ketorolac (Acular).

Do not use other eye medications during treatment with Coletyl ophthalmic except under the direction of your doctor.

Drugs other than those listed here may also interact with Coletyl ophthalmic. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Coletyl side effects

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What are the possible side effects of Coletyl?

Applies to Coletyl ophthalmic: ophthalmic solution

In addition to its needed effects, some unwanted effects may be caused by Coletyl ophthalmic. In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Coletyl ophthalmic, check with your doctor or nurse as soon as possible:

Rare

Symptoms of too much medicine being absorbed into the body

Minor Side Effects

Some of the side effects that can occur with Coletyl ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

Less common:

Coletyl contraindications

See also:
What is the most important information I should know about Coletyl?

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When pupillary constriction is undesirable e.g. acute iritis, anterior uveitis and some forms of secondary glaucoma. Acute inflammatory disease of the anterior segment. Intestinal or urinary obstruction or where increased muscular activity of the urinary or GI tract is liable to be harmful. Cardiac disease including bradycardia, heart block, recent MI; asthma; peptic ulcer; hypotension; vagotonia; epilepsy; parkinsonism; hyperthyroidism; pregnancy.

Active ingredient matches for Coletyl:

Carbachol


List of Coletyl substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Injectable; Injection; Carbachol 1 mg / ml
Injectable; Injection; Carbachol 1 mg / ml
MIO CHOL INJECTION 1 vial / 1 ML injection each (Appasamy Ocular Device Pvt Ltd)$ 0.34

References

  1. DailyMed. "CARBACHOL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "carbachol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "carbachol". http://www.drugbank.ca/drugs/DB00411 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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