What is Desloratadin Apotex?
Desloratadin Apotex is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Desloratadin Apotex is used to treat the symptoms of allergies, such as sneezing, watery eyes, and runny nose. It is also used to treat skin hives and itching in people with chronic skin reactions.
Desloratadin Apotex may also be used for purposes not listed in this medication guide.
Desloratadin Apotex indications
1.1 Seasonal Allergic Rhinitis
Desloratadin Apotex Tablets are indicated for the relief of the nasal and non-nasal symptoms of seasonal allergic rhinitis in patients 12 years of age and older.
1.2 Perennial Allergic Rhinitis
Desloratadin Apotex Tablets are indicated for the relief of the nasal and non-nasal symptoms of perennial allergic rhinitis in patients 12 years of age and older.
1.3 Chronic Idiopathic Urticaria
Desloratadin Apotex Tablets are indicated for the symptomatic relief of pruritus, reduction in the number of hives, and size of hives, in patients with chronic idiopathic urticaria 12 years of age and older.
How should I use Desloratadin Apotex?
Use Desloratadin Apotex orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Desloratadin Apotex orally disintegrating tablets. Talk to your pharmacist if you have questions about this information.
- Take Desloratadin Apotex orally disintegrating tablets by mouth with or without food.
- Do not remove the blister from the outer pouch until you are ready to take Desloratadin Apotex orally disintegrating tablets. Make sure that your hands are dry when you open the blister pack. Do not push the tablet through the foil. Peel back the foil on the blister pack and place the tablet on your tongue. The tablet dissolves quickly and can be swallowed with saliva. Desloratadin Apotex orally disintegrating tablets may be taken with or without water. Take the tablet immediately after opening the blister pack. Do not store the removed tablet for future use.
- If you miss a dose of Desloratadin Apotex orally disintegrating tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Desloratadin Apotex orally disintegrating tablets.
Uses of Desloratadin Apotex in details
Use: Labeled Indications
Allergic rhinitis: Relief of nasal and non-nasal symptoms of seasonal (SAR) and perennial (PAR) allergic rhinitis
Urticaria: Symptomatic relief of pruritus, reduction in number of hives, and reduction in size of hives associated with chronic idiopathic urticaria (CIU)
Off Label Uses
NSAID-associated urticaria (prophylaxis)
Data from a retrospective study with a limited number of patients suggest that Desloratadin Apotex may be beneficial for prophylactic therapy in patients with NSAID-associated urticaria prior to receiving a strong COX-1 inhibitor. Additional trials may be needed to further define the role of Desloratadin Apotex in this setting.
Desloratadin Apotex description
Desloratadin Apotex Tab: Each tablet contains 5.0 mg of Desloratadin Apotex.
Desloratadin Apotex Syr: Each mL of Desloratadin Apotex syrup contains 500 mcg of Desloratadin Apotex.
Excipients/Inactive Ingredients: Desloratadin Apotex Tab: Dibasic calcium phosphate dihydrate, microcrystalline cellulose, maize starch, talc, blue color film-coat material, clear film coat material, white wax and carnauba wax.
Desloratadin Apotex dosage
Desloratadin Apotex Dosage
Generic name: Desloratadin Apotex 5mg
Dosage form: tablet, film coated; oral solution
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Although an orally disintegrating tablet formulation of Desloratadin Apotex may be available in the marketplace, Desloratadin Apotex® RediTabs® Tablets are no longer marketed.
Desloratadin Apotex Tablets,
Oral Solution, or RediTabs Tablets may be taken without regard to meals. Place Desloratadin Apotex (Desloratadin Apotex) RediTabs Tablets on the tongue and allow to disintegrate before swallowing. Tablet disintegration occurs rapidly. Administer with or without water. Take tablet immediately after opening the blister.
The age-appropriate dose of Desloratadin Apotex
Oral Solution should be administered with a commercially available measuring dropper or syringe that is calibrated to deliver 2 mL and 2.5 mL (½ teaspoon).
Adults and Adolescents 12 Years of Age and Over
The recommended dose of Desloratadin Apotex Tablets or Desloratadin Apotex Tablets is one 5-mg tablet once daily. The recommended dose of Desloratadin Apotex
Oral Solution is 2 teaspoonfuls (5 mg in 10 mL) once daily.
Children 6 to 11 Years of Age
The recommended dose of Desloratadin Apotex
Oral Solution is 1 teaspoonful (2.5 mg in 5 mL) once daily. The recommended dose of Desloratadin Apotex Tablets is one 2.5-mg tablet once daily.
Children 12 Months to 5 Years of Age
The recommended dose of Desloratadin Apotex
Oral Solution is ½ teaspoonful (1.25 mg in 2.5 mL) once daily.
Children 6 to 11 Months of Age
The recommended dose of Desloratadin Apotex
Oral Solution is 2 mL (1 mg) once daily.
Adults with Hepatic or Renal Impairment
In adult patients with liver or renal impairment, a starting dose of one 5-mg tablet every other day is recommended based on pharmacokinetic data. Dosing recommendation for children with liver or renal impairment cannot be made due to lack of data.
More about Desloratadin Apotex (Desloratadin Apotex)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 5 Reviews - Add your own review/rating
- Generic Availability
Consumer resources
- Desloratadin Apotex
- Desloratadin Apotex syrup
- Desloratadin Apotex (Advanced Reading)
Professional resources
- Desloratadin Apotex (AHFS Monograph)
- Desloratadin Apotex (FDA)
Other formulations
- Desloratadin Apotex-D 24 Hour
- Desloratadin Apotex-D 12 Hour
- Desloratadin Apotex
Related treatment guides
- Allergic Rhinitis
- Urticaria
Desloratadin Apotex interactions
See also:
What other drugs will affect Desloratadin Apotex?
Inhibitors Of Cytochrome P450 3A4
In controlled clinical studies co-administration of Desloratadin Apotex with ketoconazole, erythromycin, or azithromycin resulted in increased plasma concentrations of Desloratadin Apotex and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Desloratadin Apotex.
Fluoxetine
In controlled clinical studies co-administration of Desloratadin Apotex with fluoxetine, a selective serotonin reuptake inhibitor (SSRI), resulted in increased plasma concentrations of Desloratadin Apotex and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Desloratadin Apotex.
Cimetidine
In controlled clinical studies co-administration of Desloratadin Apotex with cimetidine, a histamine H2-receptor antagonist, resulted in increased plasma concentrations of Desloratadin Apotex and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Desloratadin Apotex.
Drug Abuse And Dependence
There is no information to indicate that abuse or dependency occurs with Desloratadin Apotex Tablets.
Desloratadin Apotex side effects
See also:
What are the possible side effects of Desloratadin Apotex?
In clinical trials in a range of indications including allergic rhinitis and chronic idiopathic urticaria, at the recommended dose of 5 mg daily, undesirable effects with Desloratadin Apotex tablets were reported in 3 % of patients in excess of those treated with placebo. The most frequent adverse events reported in excess of placebo were fatigue (1.2 %), dry mouth (0.8 %), and headache (0.6 %).
Very rare cases of hypersensitivity reactions (including anaphylaxis and rash) tachycardia, palpitations, psychomotor hyperactivity, seizures, elevations of liver enzymes, hepatitis, and increased bilirubin have been reported during the marketing of Desloratadin Apotex.
Desloratadin Apotex Syr: In clinical trials in a paediatric population, Desloratadin Apotex Syrup was administered to a total of 246 children aged 6 months through 11 years. The overall incidence of adverse events in children 2 through 11 years of age was similar for Desloratadin Apotex Syrup and the placebo groups. In infants and toddlers aged 6 to 23 months, the most frequent adverse events reported in excess of placebo were diarrhea (3.7%), fever (2.3%) and insomnia (2.3%).
Desloratadin Apotex contraindications
See also:
What is the most important information I should know about Desloratadin Apotex?
You should not take this medication if you are allergic to Desloratadin Apotex or to loratadine (Claritin).
Before taking Desloratadin Apotex, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.
Do not give this medication to a child younger than 2 years old without the advice of a doctor.
Desloratadin Apotex disintegrating tablets (Desloratadin Apotex) may contain phenylalanine. Talk to your doctor before using this form of Desloratadin Apotex if you have phenylketonuria (PKU).
Active ingredient matches for Desloratadin Apotex:
Desloratadine in Czech Republic.
References
- DailyMed. "DESLORATADINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "Desloratadine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Desloratadine". http://www.drugbank.ca/drugs/DB00967 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Desloratadin Apotex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Desloratadin Apotex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
