• Dextroamphetamine ER indications
• Uses of Dextroamphetamine ER in details
• Dextroamphetamine ER description
• Dextroamphetamine ER dosage
• Dextroamphetamine ER interactions
• Dextroamphetamine ER side effects
• Dextroamphetamine ER contraindications

What is Dextroamphetamine ER?

Dextroamphetamine ER is used to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy (uncontrollable desire for sleep or a sudden attack of deep sleep). It belongs to the group of medicines called central nervous system (CNS) stimulants.

Dextroamphetamine ER works in the treatment of ADHD by increasing attention and decreasing restlessness in children and adults who are overactive, cannot concentrate for very long, or are easily distracted and impulsive. Dextroamphetamine ER is used as part of a total treatment program that also includes social, educational, and psychological treatment.

Dextroamphetamine ER is available only with a doctor's prescription. Prescriptions cannot be refilled. A new prescription must be obtained from your doctor each time you or your child needs Dextroamphetamine ER.

Dextroamphetamine ER indications

Dextroamphetamine ER Tablets USP are indicated for:

1. Narcolepsy.

2. Attention Deficit Disorder with Hyperactivity, as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in pediatric patients (ages 3 to 16 years) with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate to severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity. The diagnosis of this syndrome should not be made with finality when these symptoms are only of comparatively recent origin. Nonlocalizing (soft) neurological signs, learning disability, and abnormal EEG may or may not be present, and a diagnosis of central nervous system dysfunction may or may not be warranted.

How should I use Dextroamphetamine ER?

Use Dextroamphetamine ER as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Dextroamphetamine ER comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Dextroamphetamine ER refilled.
• Take Dextroamphetamine ER by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Take your doses of Dextroamphetamine ER 4 to 6 hours apart unless your doctor tells you otherwise.
• Do not drink fruit juice at the same time that you take Dextroamphetamine ER. Certain fruit juices (eg, grapefruit, apple, orange) may decrease Dextroamphetamine ER's effectiveness.
• Take Dextroamphetamine ER on a regular schedule to get the most benefit from it. Taking Dextroamphetamine ER at the same time each day will help you remember to take it.
• If you miss a dose of Dextroamphetamine ER, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dextroamphetamine ER.

Uses of Dextroamphetamine ER in details

This medication is used to treat attention deficit hyperactivity disorder - ADHD. It works by changing the amounts of certain natural substances in the brain. Dextroamphetamine ER belongs to a class of drugs known as stimulants. It can help increase your ability to pay attention, stay focused on an activity, and control behavior problems. It may also help you to organize your tasks and improve listening skills.

This drug is also used to treat a certain sleeping disorder (narcolepsy) to help you stay awake during the day. It should not be used to treat tiredness or to hold off sleep in people who do not have a sleep disorder.

How to use Das

Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking Dextroamphetamine ER and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually 1-3 times a day. The first dose is usually taken when you wake up in the morning. If more doses are prescribed, take them as directed by your doctor, usually 4-6 hours apart. Taking this medication late in the day may cause trouble sleeping (insomnia).

The dosage is based on your medical condition and response to treatment. Your doctor may adjust your dose to find the dose that is best for you. Follow your doctor's instructions carefully.

Swallow the capsules whole. Do not crush or chew the capsules. Doing so can release all of the drug at once, increasing the risk of side effects.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

During treatment, your doctor may occasionally recommend stopping the medication for a short time to see whether there are any changes in your behavior and whether the medication is still needed.

This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (including severe tiredness, sleep problems, mental/mood changes such as depression) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away.

Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction. Do not increase your dose or use this drug more often or for longer than prescribed. Properly stop this medication when so directed.

When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.

Tell your doctor if your condition does not improve or if it worsens.

Dextroamphetamine ER description

Dextroamphetamine ER is a chiral compound. The racemic mixture can be divided into its optical antipodes: levo- and dextro-amphetamine. Dextroamphetamine ER is the parent compound of its own structural class, comprising a broad range of psychoactive derivatives, e.g., MDMA (Ecstasy) and the N-methylated form, methamphetamine. Dextroamphetamine ER is a homologue of phenethylamine.

Dextroamphetamine ER dosage

Dextroamphetamine ER Dosage

Generic name: Dextroamphetamine ER

Dosage form: tablets

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Amphetamines should be administered at the lowest effective dosage and dosage should be individually adjusted. Late evening doses should be avoided because of the resulting insomnia.

Narcolepsy: Usual dose is 5 to 60 mg per day in divided doses, depending on the individual patient response.

Narcolepsy seldom occurs in pediatric patients under 12 years of age; however, when it does, Dextroamphetamine ER® (Dextroamphetamine ER) may be used. The suggested initial dose for patients aged 6 to 12 is 5 mg daily; daily dose may be raised in increments of 5 mg at weekly intervals until optimal response is obtained. In patients 12 years of age and older, start with 10 mg daily, daily dosage may be raised in increments of 10 mg at weekly intervals until an optimal response is obtained. If bothersome adverse reactions appear (e.g., insomnia or anorexia), dosage should be reduced. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours.

Attention Deficit Disorder with Hyperactivity: Not recommended for pediatric patients under 3 years of age.

In pediatric patients from 3 to 5 years of age, start with 2.5 mg daily, by tablet; daily dosage may be raised in increments of 2.5 mg at weekly intervals until optimal response is obtained.

In pediatric patients 6 years of age and older, start with 5 mg once or twice daily; daily dosage may be raised in increments of 5 mg at weekly intervals until optimal response is obtained. Only in rare cases will it be necessary to exceed a total of 40 mg per day.

Give first dose on awakening: additional doses (1 or 2) at intervals of 4 to 6 hours.

Where possible, drug administration should be interrupted occasionally to determine if there is a recurrence of behavioral symptoms sufficient to require continued therapy.

More about Dextroamphetamine ER (Dextroamphetamine ER)

• Side Effects
• During Pregnancy or Breastfeeding
• Dosage Information
• Drug Images
• Drug Interactions
• Support Group
• 3 Reviews - Add your own review/rating

Consumer resources

• Dextroamphetamine ER (Advanced Reading)

• Other brands: Dexedrine, Zenzedi, ProCentra, Liquadd

Professional resources

• Dextroamphetamine ER (FDA)
• Dextroamphetamine ER (AHFS Monograph)

Related treatment guides

• ADHD
• Narcolepsy

Dextroamphetamine ER interactions

See also:
What other drugs will affect Dextroamphetamine ER?

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.

Check the labels on all your medicines (such as cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about using these products safely.

Dextroamphetamine ER is very similar to amphetamine or lisdexamfetamine. Do not use medications containing amphetamine or lisdexamfetamine while using Dextroamphetamine ER.

This medication may interfere with certain medical/laboratory tests (including blood and urine steroid levels, brain scan for Parkinson's disease), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Dextroamphetamine ER side effects

See also:
What are the possible side effects of Dextroamphetamine ER?

Applies to Dextroamphetamine ER: oral capsule extended release, oral solution, oral tablet

In addition to its needed effects, some unwanted effects may be caused by Dextroamphetamine ER. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Dextroamphetamine ER:

Rare

• Agitation
• delusions
• seeing, hearing, or feeling things that are not there

Incidence not known:

• Blurred vision
• chest discomfort or pain
• difficulty breathing
• dizziness
• faintness
• false or unusual sense of well-being
• fast, pounding, or irregular heartbeat or pulse
• headache
• pounding in the ears
• shakiness in the legs, arms, hands, or feet
• swelling of the feet or lower legs
• trembling or shaking of the hands or feet
• troubled breathing
• twitching, twisting, or uncontrolled repetitive movements of tongue, lips, face, arms, or legs
• unable to sleep
• uncontrolled vocal outbursts and/or tics (uncontrolled repeated body movements)
• unusual tiredness or weakness

If any of the following symptoms of overdose occur while taking Dextroamphetamine ER, get emergency help immediately:

Symptoms of overdose:

• Change in consciousness
• dark-colored urine
• diarrhea
• discouragement
• feeling sad or empty
• fever
• irritability
• lack of appetite
• loss of consciousness
• loss of interest or pleasure
• mood or mental changes
• muscle cramps or spasms
• muscle pain or stiffness
• nausea
• panic state
• physical attempt to injure
• rapid breathing
• seizures
• stomach cramps
• sweating
• trouble concentrating
• violent actions
• vomiting

Minor Side Effects

Some of the side effects that can occur with Dextroamphetamine ER may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known:

• Bad, unusual, or unpleasant (after) taste
• change in taste
• constipation
• decreased interest in sexual intercourse
• dry mouth
• hives or welts, itching, or skin rash
• inability to have or keep an erection
• indigestion
• loss in sexual ability, desire, drive, or performance
• passing of gas
• redness of the skin
• weight loss

Dextroamphetamine ER contraindications

See also:
What is the most important information I should know about Dextroamphetamine ER?

Hypersensitivity (eg, angioedema, anaphylaxis) or idiosyncrasy to amphetamine, Dextroamphetamine ER, other sympathomimetic amines, or any component of the formulation; advanced arteriosclerosis, symptomatic cardiovascular disease, moderate-to-severe hypertension; hyperthyroidism; glaucoma; agitated states; history of drug abuse; during or within 14 days of stopping monoamine oxidase inhibitor (MAOI) therapy (including MAOIs such as linezolid or intravenous methylene blue).

Documentation of allergenic cross-reactivity for amphetamines is limited. However, because of similarities in chemical structure and/or pharmacologic actions, the possibility of cross-sensitivity cannot be ruled out with certainty.

Active ingredient matches for Dextroamphetamine ER:

Dextroamphetamine Sulfate

List of Dextroamphetamine ER substitutes (brand and generic names)	Sort by popularity
Unit description / dosage (Manufacturer)	Price, USD
Das
Dexedrine Tablets
Dextroamphetamine
Tablet; Oral; Dextroamphetamine Sulfate 5 mg
Capsule, Extended Release; Oral; Dextroamphetamine Sulfate 5 mg
Capsule, Extended Release; Oral; Dextroamphetamine Sulfate 10 mg
Capsule, Extended Release; Oral; Dextroamphetamine Sulfate 15 mg
Tablet; Oral; Dextroamphetamine Sulfate 10 mg
Tablet; Oral; 5 mg
Solution; Oral; Dextroamphetamine Sulfate 5 mg / 5 ml
Tablet; Oral; Dextroamphetamine Sulfate 15 mg
D-amphetamine sulfate powder	$ 900.00
Desoxyn 5 mg tablet	$ 5.10
Dexedrine 15 mg 24 Hour Capsule	$ 4.22
Dextroamphetamine Sulfate CR 15 mg 24 Hour Capsule	$ 3.47
Dexedrine 10 mg 24 Hour Capsule	$ 3.23
Dexedrine 5 mg 24 Hour Capsule	$ 3.00
Dextroamphetamine Sulfate CR 10 mg 24 Hour Capsule	$ 2.96
Dexedrine spansule 15 mg	$ 2.45
Dextroamphetamine Sulfate CR 5 mg 24 Hour Capsule	$ 2.06
Dexedrine spansule 10 mg	$ 1.91
Dexedrine spansule 5 mg	$ 1.91
Dexedrine 15 mg Sustained-Release Capsule	$ 1.08
Dextroamphetamine Sulfate 10 mg tablet	$ 0.92
Dexedrine 10 mg Sustained-Release Capsule	$ 0.89
Dextroamphetamine Sulfate 5 mg tablet	$ 0.65
Dexedrine 5 mg Tablet	$ 0.62
Dextroamphetamine 10 mg tablet	$ 0.56
Dextrostat 10 mg tablet	$ 0.48
Dextroamphetamine 5 mg tablet	$ 0.28
Dextrostat 5 mg tablet	$ 0.25
Dextroamphetamine solution 5 mg/5mL (Tris Pharma Inc (US))
Dextroamphetamine Extended-Release Capsules
DextroStat
Tablet; Oral; Dextroamphetamine Sulfate 5 mg
Tablet; Oral; Dextroamphetamine Sulfate 10 mg

References

1. DailyMed. "DEXTROAMPHETAMINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. PubChem. "dextroamphetamine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
3. DrugBank. "dextroamphetamine". http://www.drugbank.ca/drugs/DB01576 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Dextroamphetamine ER are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dextroamphetamine ER. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology