What is Dometin?
Dometin is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Dometin is used to treat the symptoms of allergies, such as sneezing, watery eyes, and runny nose. It is also used to treat skin hives and itching in people with chronic skin reactions.
Dometin may also be used for purposes not listed in this medication guide.
Dometin indications
1.1 Seasonal Allergic Rhinitis
Dometin Tablets are indicated for the relief of the nasal and non-nasal symptoms of seasonal allergic rhinitis in patients 12 years of age and older.
1.2 Perennial Allergic Rhinitis
Dometin Tablets are indicated for the relief of the nasal and non-nasal symptoms of perennial allergic rhinitis in patients 12 years of age and older.
1.3 Chronic Idiopathic Urticaria
Dometin Tablets are indicated for the symptomatic relief of pruritus, reduction in the number of hives, and size of hives, in patients with chronic idiopathic urticaria 12 years of age and older.
How should I use Dometin?
Use Dometin orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Dometin orally disintegrating tablets. Talk to your pharmacist if you have questions about this information.
- Take Dometin orally disintegrating tablets by mouth with or without food.
- Do not remove the blister from the outer pouch until you are ready to take Dometin orally disintegrating tablets. Make sure that your hands are dry when you open the blister pack. Do not push the tablet through the foil. Peel back the foil on the blister pack and place the tablet on your tongue. The tablet dissolves quickly and can be swallowed with saliva. Dometin orally disintegrating tablets may be taken with or without water. Take the tablet immediately after opening the blister pack. Do not store the removed tablet for future use.
- If you miss a dose of Dometin orally disintegrating tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Dometin orally disintegrating tablets.
Uses of Dometin in details
Use: Labeled Indications
Allergic rhinitis: Relief of nasal and non-nasal symptoms of seasonal (SAR) and perennial (PAR) allergic rhinitis
Urticaria: Symptomatic relief of pruritus, reduction in number of hives, and reduction in size of hives associated with chronic idiopathic urticaria (CIU)
Off Label Uses
NSAID-associated urticaria (prophylaxis)
Data from a retrospective study with a limited number of patients suggest that Dometin may be beneficial for prophylactic therapy in patients with NSAID-associated urticaria prior to receiving a strong COX-1 inhibitor. Additional trials may be needed to further define the role of Dometin in this setting.
Dometin description
Dometin Tab: Each tablet contains 5.0 mg of Dometin.
Dometin Syr: Each mL of Dometin syrup contains 500 mcg of Dometin.
Excipients/Inactive Ingredients: Dometin Tab: Dibasic calcium phosphate dihydrate, microcrystalline cellulose, maize starch, talc, blue color film-coat material, clear film coat material, white wax and carnauba wax.
Dometin dosage
Dometin Dosage
Generic name: Dometin 5mg
Dosage form: tablet, film coated; oral solution
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Although an orally disintegrating tablet formulation of Dometin may be available in the marketplace, Dometin® RediTabs® Tablets are no longer marketed.
Dometin Tablets,
Oral Solution, or RediTabs Tablets may be taken without regard to meals. Place Dometin (Dometin) RediTabs Tablets on the tongue and allow to disintegrate before swallowing. Tablet disintegration occurs rapidly. Administer with or without water. Take tablet immediately after opening the blister.
The age-appropriate dose of Dometin
Oral Solution should be administered with a commercially available measuring dropper or syringe that is calibrated to deliver 2 mL and 2.5 mL (½ teaspoon).
Adults and Adolescents 12 Years of Age and Over
The recommended dose of Dometin Tablets or Dometin Tablets is one 5-mg tablet once daily. The recommended dose of Dometin
Oral Solution is 2 teaspoonfuls (5 mg in 10 mL) once daily.
Children 6 to 11 Years of Age
The recommended dose of Dometin
Oral Solution is 1 teaspoonful (2.5 mg in 5 mL) once daily. The recommended dose of Dometin Tablets is one 2.5-mg tablet once daily.
Children 12 Months to 5 Years of Age
The recommended dose of Dometin
Oral Solution is ½ teaspoonful (1.25 mg in 2.5 mL) once daily.
Children 6 to 11 Months of Age
The recommended dose of Dometin
Oral Solution is 2 mL (1 mg) once daily.
Adults with Hepatic or Renal Impairment
In adult patients with liver or renal impairment, a starting dose of one 5-mg tablet every other day is recommended based on pharmacokinetic data. Dosing recommendation for children with liver or renal impairment cannot be made due to lack of data.
More about Dometin (Dometin)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 5 Reviews - Add your own review/rating
- Generic Availability
Consumer resources
- Dometin
- Dometin syrup
- Dometin (Advanced Reading)
Professional resources
- Dometin (AHFS Monograph)
- Dometin (FDA)
Other formulations
- Dometin-D 24 Hour
- Dometin-D 12 Hour
- Dometin
Related treatment guides
- Allergic Rhinitis
- Urticaria
Dometin interactions
See also:
What other drugs will affect Dometin?
Inhibitors Of Cytochrome P450 3A4
In controlled clinical studies co-administration of Dometin with ketoconazole, erythromycin, or azithromycin resulted in increased plasma concentrations of Dometin and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Dometin.
Fluoxetine
In controlled clinical studies co-administration of Dometin with fluoxetine, a selective serotonin reuptake inhibitor (SSRI), resulted in increased plasma concentrations of Dometin and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Dometin.
Cimetidine
In controlled clinical studies co-administration of Dometin with cimetidine, a histamine H2-receptor antagonist, resulted in increased plasma concentrations of Dometin and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Dometin.
Drug Abuse And Dependence
There is no information to indicate that abuse or dependency occurs with Dometin Tablets.
Dometin side effects
See also:
What are the possible side effects of Dometin?
In clinical trials in a range of indications including allergic rhinitis and chronic idiopathic urticaria, at the recommended dose of 5 mg daily, undesirable effects with Dometin tablets were reported in 3 % of patients in excess of those treated with placebo. The most frequent adverse events reported in excess of placebo were fatigue (1.2 %), dry mouth (0.8 %), and headache (0.6 %).
Very rare cases of hypersensitivity reactions (including anaphylaxis and rash) tachycardia, palpitations, psychomotor hyperactivity, seizures, elevations of liver enzymes, hepatitis, and increased bilirubin have been reported during the marketing of Dometin.
Dometin Syr: In clinical trials in a paediatric population, Dometin Syrup was administered to a total of 246 children aged 6 months through 11 years. The overall incidence of adverse events in children 2 through 11 years of age was similar for Dometin Syrup and the placebo groups. In infants and toddlers aged 6 to 23 months, the most frequent adverse events reported in excess of placebo were diarrhea (3.7%), fever (2.3%) and insomnia (2.3%).
Dometin contraindications
See also:
What is the most important information I should know about Dometin?
You should not take this medication if you are allergic to Dometin or to loratadine (Claritin).
Before taking Dometin, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.
Do not give this medication to a child younger than 2 years old without the advice of a doctor.
Dometin disintegrating tablets (Dometin) may contain phenylalanine. Talk to your doctor before using this form of Dometin if you have phenylketonuria (PKU).
Active ingredient matches for Dometin:
Desloratadine in Vietnam.
Indometacin in Netherlands.
| Unit description / dosage (Manufacturer) | Price, USD |
| Dometin 5 mg x 1 Blister x 10 Tablet | |
| Dometin 5 mg x 3 Blister x 10 Tablet | |
List of Dometin substitutes (brand and generic names): | |
| Dolovin (Portugal) | |
| Domicap (Malaysia) | |
| Donica (India) | |
| Donica 25mg CAP / 10 (IPCA Laboratories Ltd.) | $ 0.26 |
| 25 mg x 10's (IPCA Laboratories Ltd.) | $ 0.26 |
| Donica 25 mg Capsule (IPCA Laboratories Ltd.) | $ 0.03 |
| DONICA 25 MG CAPSULE 1 strip / 10 capsules each (IPCA Laboratories Ltd.) | $ 0.40 |
| DONICA 75 MG CAPSULE SR 1 strip / 10 capsule srs each (IPCA Laboratories Ltd.) | $ 0.94 |
| DONICA cap 25 mg x 10's (IPCA Laboratories Ltd.) | $ 0.26 |
| Donica 25mg Capsule (IPCA Laboratories Ltd.) | $ 0.04 |
| Donica 75mg Capsule SR (IPCA Laboratories Ltd.) | $ 0.10 |
| Donica-SR (India) | |
| Donica-SR 75mg INJ / 10 (IPCA) | $ 0.64 |
| DONICA-SR cap 75 mg x 10's (IPCA) | $ 0.74 |
| Dora (Bangladesh) | |
| Doxafin (Turkey) | |
| Doxtadin (Bosnia & Herzegowina) | |
| Dozanavir (Vietnam) | |
| Dozanavir 5 mg x 3 Blister x 10 Tablet | |
| Dozanavir 5 mg x 6 Blister x 10 Tablet | |
| Dozanavir 5 mg x 10 Blister x 10 Tablet | |
| Dozanavir 5 mg x 1 Bottle 100 Tablet | |
| Dozanavir 5 mg x 1 Bottle 250 Tablet | |
| Dozanavir 5 mg x 1 Bottle 500 Tablet | |
| Draxil (Mexico) | |
| Ducain (India) | |
| Ducain 25mg CAP / 10 (Neon Laboratories Ltd) | $ 3.01 |
| 25 mg x 10's (Neon Laboratories Ltd) | $ 3.01 |
| Ducain 25 mg Capsule (Neon Laboratories Ltd) | $ 0.03 |
| DUCAIN cap 25 mg x 10's (Neon Laboratories Ltd) | $ 3.01 |
| Durametacin (Germany) | |
| DYL (India) | |
| DYL Capsule/ Tablet / 5mg / 10 units (Ajanta Pharma Ltd.) | $ 0.43 |
| Dyl 5mg FC-TAB / 10 (Ajanta Pharma Ltd.) | $ 0.43 |
| 5 mg x 10's (Ajanta Pharma Ltd.) | $ 0.43 |
| DYL 5 mg Tablet (Ajanta Pharma Ltd.) | $ 0.04 |
| DYL 5MG TABLET 1 strip / 10 tablets each (Ajanta Pharma Ltd.) | $ 0.44 |
| DYL film-coated tab 5 mg x 10's (Ajanta Pharma Ltd.) | $ 0.43 |
| Dyl 5mg FC-TAB / 10 (Ajanta Pharma Ltd.) | $ 0.43 |
| Dyl 5mg Tablet (Ajanta Pharma Ltd.) | $ 0.04 |
| Dyl-D (India) | |
| Dyl-D Pseudoephedrine hydrochloride180 mg, Desloratadine 5 mg. TAB / 10 (Ajanta) | $ 0.48 |
| 10's (Ajanta) | $ 0.48 |
| DYL-D tab 10's (Ajanta) | $ 0.48 |
| Dynametcin (South Africa) | |
| Dynid (Bulgaria, Poland) | |
| Efestad (Bulgaria, Italy) | |
| Elaroten (Serbia) | |
See 1631 substitutes for Dometin | |
References
- DailyMed. "DESLORATADINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "Desloratadine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Desloratadine". http://www.drugbank.ca/drugs/DB00967 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Dometin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dometin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet1 consumer reported age
| Users | % | ||
|---|---|---|---|
| 16-29 | 1 | 100.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
