What is Galferol 2400?
Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are available in the foods that you eat. Vitamin D is necessary for strong bones and teeth.
Lack of vitamin D may lead to a condition called rickets, especially in children, in which bones and teeth are weak. In adults it may cause a condition called osteomalacia, in which calcium is lost from bones so that they become weak. Your doctor may treat these problems by prescribing vitamin D for you. Vitamin D is also sometimes used to treat other diseases in which calcium is not used properly by the body.
Galferol 2400 is the form of vitamin D used in vitamin supplements.
Some conditions may increase your need for vitamin D. These include:
- Alcoholism
- Intestine diseases
- Kidney disease
- Liver disease
- Overactivity of the parathyroid glands with kidney failure
- Pancreas disease
- Surgical removal of stomach
In addition, individuals and breast-fed infants who lack exposure to sunlight, as well as dark-skinned individuals, may be more likely to have a vitamin D deficiency. Increased need for vitamin D should be determined by your health care professional.
Alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are forms of vitamin D used to treat hypocalcemia (not enough calcium in the blood). Alfacalcidol, calcifediol, and calcitriol are also used to treat certain types of bone disease that may occur with kidney disease in patients who are undergoing kidney dialysis.
Claims that vitamin D is effective for treatment of arthritis and prevention of nearsightedness or nerve problems have not been proven. Some psoriasis patients may benefit from vitamin D supplements; however, controlled studies have not been performed.
Injectable vitamin D is given by or under the supervision of a health care professional. Some strengths of Galferol 2400 and all strengths of alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are available only with your doctor's prescription. Other strengths of Galferol 2400 are available without a prescription. However, it may be a good idea to check with your health care professional before taking vitamin D on your own. Taking large amounts over long periods may cause serious unwanted effects.
Galferol 2400 indications
Galferol 2400 (Galferol 2400 capsules) is indicated for use in the treatment of hypoparathyroidism, refractory rickets, also known as vitamin D resistant rickets, and familial hypophosphatemia.
How should I use Galferol 2400?
Use Galferol 2400 solution as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.
- Use the dropper than comes with Galferol 2400 solution to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Drop the dose of Galferol 2400 solution directly into the mouth or you may mix it with milk, formula, fruit juice, cereal, fruit, dessert, or other liquid or semisolid liquids.
- If you miss taking a dose of Galferol 2400 solution for 1 or more days, there is no cause for concern. If your doctor recommended that you take it, try to remember your dose every day.
Ask your health care provider any questions you may have about how to use Galferol 2400 solution.
Uses of Galferol 2400 in details
Use: Labeled Indications
Dietary supplement: For use as a vitamin D supplement.
Hypoparathyroidism: Treatment of hypoparathyroidism. Note: Since parathyroid hormone (PTH) is required for the conversion of vitamin D (Galferol 2400 or cholecalciferol) to the active metabolite of vitamin D (1,25-dihydroxyvitamin D), alternative vitamin D preparations not dependent on this conversion (eg, alfacalcidol, calcitriol) are recommended for routine use (Endocrine Society [Brandi 2016]).
Off Label Uses
Osteoporosis, prevention
Based on the Clinician's Guide to Prevention and Treatment of Osteoporosis from the National Osteoporosis Foundation (NOF), adequate intake of vitamin D (through dietary sources and/or supplementation with Galferol 2400 [or cholecalciferol] if needed) is effective and recommended for the prevention of osteoporosis.
Vitamin D insufficiency/deficiency
Based on the National Osteoporosis Foundation (NOF) Clinician's Guide to Prevention and Treatment of Osteoporosis, supplemental cholecalciferol (or Galferol 2400) may be used for the prevention or treatment of vitamin D deficiency to achieve desired serum 25(OH)D levels.
Vitamin D insufficiency/deficiency in patients with chronic kidney disease, treatment
Based on the Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease–mineral and bone disorder (CKD-MBD), vitamin D insufficiency/deficiency in patients without severe and progressive hyperparathyroidism, including chronic kidney disease stages G3 to G5 and dialysis or transplant patients, should be corrected using treatment strategies recommended for the general population, which includes repletion with Galferol 2400 (or cholecalciferol).
Galferol 2400 description
Galferol 2400 (Vitamin D2) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond. It differs from cholecalciferol in having a double bond between C22 and C23 and a methyl group at C24. [PubChem]
Galferol 2400 dosage
Galferol 2400 Dosage
Generic name: Galferol 2400 1.25mg
Dosage form: capsule, liquid filled
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
THE RANGE BETWEEN THERAPEUTIC AND TOXIC DOSES IS NARROW.
Vitamin D Resistant Rickets: 12,000 to 500,000 IU units daily.
Hypoparathyroidism: 50,000 to 200,000 IU units daily concomitantly with calcium lactate 4 g, six times per day.
DOSAGE MUST BE INDIVIDUALIZED UNDER CLOSE MEDICAL SUPERVISION.
Calcium intake should be adequate. Blood calcium and phosphorus determinations must be made every 2 weeks or more frequently if necessary.
X-rays of the bones should be taken every month until condition is corrected and stabilized.
More about Galferol 2400 (Galferol 2400)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 0 Reviews - Add your own review/rating
- Generic Availability
Consumer resources
- Galferol 2400
- Galferol 2400 solution
- Other brands: Vitamin D2, Galferol 2400, Galferol 2400
Professional resources
- Galferol 2400 (AHFS Monograph)
- Galferol 2400 (FDA)
Related treatment guides
- Familial Hypophosphatemia
- Hypocalcemia
- Hypoparathyroidism
- Hypophosphatemia
- Osteomalacia
- More (4) »
Galferol 2400 interactions
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What other drugs will affect Galferol 2400?
increases conc of magnesium-containing antacids leading to hypermagnaesemia in patients on chronic renal dialysis. Increases digitalis glycoside conc resulting in hypercalcaemia and may precipitate cardiac arrhythmia. Increases verapamil conc resulting in atrial fibrillation. Cholestyramine and prolonged use of mineral oil decrease Galferol 2400 absorption in the intestines. Thiazide diuretics may cause hypercalcaemia in hypoparathyroid patients on vit D therapy.
Food Interaction
Concomitant vit D intake with fortified foods, dietary supplements requires a limited vit D diet.
Galferol 2400 side effects
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What are the possible side effects of Galferol 2400?
Applies to Galferol 2400: oral capsules and solution
Side effects include:
Possible hypervitaminosis D effects: polyuria, nocturia, polydipsia, hypercalciuria, reversible azotemia, hypertension, nephrocalcinosis, generalized vascular calcification, irreversible renal insufficiency (may be fatal), mental retardation, widespread soft tissue calcification, osteoporosis, dwarfism, vague aches, stiffness, weakness, nausea, anorexia, constipation, mild acidosis, anemia, weight loss.
Galferol 2400 contraindications
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What is the most important information I should know about Galferol 2400?
Hypercalcemia; malabsorption syndrome; abnormal sensitivity to the toxic effects of vitamin D; hypervitaminosis D
Note: Although the manufacturer's labeling lists use in malabsorption syndrome as contraindicated, when dosed appropriately, Galferol 2400 may be used in these patients (AACE/ACE [Camacho 2016]; Dawson-Hughes 2018).
Documentation of allergenic cross-reactivity for vitamin D analogues is limited. However, because of similarities in chemical structure and/or pharmacologic actions, the possibility of cross-sensitivity cannot be ruled out with certainty.
Active ingredient matches for Galferol 2400:
Ergocalciferol in Argentina.
List of Galferol 2400 substitutes (brand and generic names) | Sort by popularity |
Unit description / dosage (Manufacturer) | Price, USD |
Ergocalciférol | |
Vitamin d 400 unit softgel | $ 0.04 |
Longs vitamin d 400 unit tablet | $ 0.03 |
Ergocalciferol capsule, liquid filled 1.25 mg/1 (Winthrop U.S. (US)) | |
Ergocalciferol capsule 1.25 mg/1 (Dispensing Solutions, Inc. (US)) | |
Ergocalciferol Colonis (Malta) | |
Ergocalciferol L.CH. (Chile) | |
Ergocalciferol Solution | |
Ergocalciferol Winthrop (United States) | |
Ergokalciferolio (Lithuania) | |
Ergokalciferolio 0.125% Sanitas (Lithuania) | |
Ergosterol, Irradiated | |
Geltabs | |
Genevis (Chile) | |
Infadin (Czech Republic, Slovakia) | |
Infadin 20000 IU/1 mL x 1 Bottle 10 mL (Zentiva) | |
Jekovit (Finland) | |
Kalciferol SAD (Denmark) | |
Lennon-Strong Calciferol (South Africa) | |
Oleovitamin D, Synthetic | |
Ostatac (Argentina) | |
Ostelin (Argentina, Greece, Italy, Taiwan) | |
Ostelin 250 mg x 1000's (Ifet) | |
Ostelin 800 (Italy) | |
Ostelin Potencia 100 (Argentina) | |
Osto-D2 (Canada) | |
Capsule; Oral; Vitamin D2 50, 000 units | |
Osto-D2 capsule 50000 unit (Paladin Labs Inc (Canada)) | |
Raquiferol (Argentina, Peru) | |
Raquiferol D2 (Peru) | |
Sicovit D2 (Romania) | |
Stérogyl (France) | |
Solution; Oral; Vitamin D2 / Ergocalciferol 20, 000 IU / ml | |
Sterogyl (Argentina, Tunisia) | |
Solution; Oral; Vitamin D2 / Ergocalciferol 20, 000 IU / ml (Hoechst marion roussel) | |
Stérogyl (France) | |
Solution; Oral; Vitamin D2 / Ergocalciferol 20, 000 IU / ml | |
Sterovit 0.5 | |
Steùrogyl (Vietnam) | |
Tanvimil D (Argentina) | |
Uvestérol D (France, Vietnam) | |
Solution; Oral; Vitamin D2 / Ergocalciferol 1, 500 IU / ml | |
Solution; Oral; Vitamin D2 / Ergocalciferol 1, 500 IU / ml | |
Uvesterol-D | |
Vitamin D Ergocalciferol | |
Vitamin D Slovakofarma (Czech Republic, Lithuania, Slovakia) | |
Vitamin D2 | |
Vitamina D Richmond (Argentina) | |
Vitamina D2 Salf (Italy) | |
See 113 substitutes for Galferol 2400 |
References
- DailyMed. "ERGOCALCIFEROL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "ergocalciferol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "ergocalciferol". http://www.drugbank.ca/drugs/DB00153 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Galferol 2400 are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Galferol 2400. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology