What is Uvestérol D?
Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are available in the foods that you eat. Vitamin D is necessary for strong bones and teeth.
Lack of vitamin D may lead to a condition called rickets, especially in children, in which bones and teeth are weak. In adults it may cause a condition called osteomalacia, in which calcium is lost from bones so that they become weak. Your doctor may treat these problems by prescribing vitamin D for you. Vitamin D is also sometimes used to treat other diseases in which calcium is not used properly by the body.
Uvestérol D is the form of vitamin D used in vitamin supplements.
Some conditions may increase your need for vitamin D. These include:
- Alcoholism
- Intestine diseases
- Kidney disease
- Liver disease
- Overactivity of the parathyroid glands with kidney failure
- Pancreas disease
- Surgical removal of stomach
In addition, individuals and breast-fed infants who lack exposure to sunlight, as well as dark-skinned individuals, may be more likely to have a vitamin D deficiency. Increased need for vitamin D should be determined by your health care professional.
Alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are forms of vitamin D used to treat hypocalcemia (not enough calcium in the blood). Alfacalcidol, calcifediol, and calcitriol are also used to treat certain types of bone disease that may occur with kidney disease in patients who are undergoing kidney dialysis.
Claims that vitamin D is effective for treatment of arthritis and prevention of nearsightedness or nerve problems have not been proven. Some psoriasis patients may benefit from vitamin D supplements; however, controlled studies have not been performed.
Injectable vitamin D is given by or under the supervision of a health care professional. Some strengths of Uvestérol D and all strengths of alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are available only with your doctor's prescription. Other strengths of Uvestérol D are available without a prescription. However, it may be a good idea to check with your health care professional before taking vitamin D on your own. Taking large amounts over long periods may cause serious unwanted effects.
Uvestérol D indications
Uvestérol D (Uvestérol D capsules) is indicated for use in the treatment of hypoparathyroidism, refractory rickets, also known as vitamin D resistant rickets, and familial hypophosphatemia.
How should I use Uvestérol D?
Use Uvestérol D solution as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.
- Use the dropper than comes with Uvestérol D solution to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Drop the dose of Uvestérol D solution directly into the mouth or you may mix it with milk, formula, fruit juice, cereal, fruit, dessert, or other liquid or semisolid liquids.
- If you miss taking a dose of Uvestérol D solution for 1 or more days, there is no cause for concern. If your doctor recommended that you take it, try to remember your dose every day.
Ask your health care provider any questions you may have about how to use Uvestérol D solution.
Uses of Uvestérol D in details
Use: Labeled Indications
Dietary supplement: For use as a vitamin D supplement.
Hypoparathyroidism: Treatment of hypoparathyroidism. Note: Since parathyroid hormone (PTH) is required for the conversion of vitamin D (Uvestérol D or cholecalciferol) to the active metabolite of vitamin D (1,25-dihydroxyvitamin D), alternative vitamin D preparations not dependent on this conversion (eg, alfacalcidol, calcitriol) are recommended for routine use (Endocrine Society [Brandi 2016]).
Off Label Uses
Osteoporosis, prevention
Based on the Clinician's Guide to Prevention and Treatment of Osteoporosis from the National Osteoporosis Foundation (NOF), adequate intake of vitamin D (through dietary sources and/or supplementation with Uvestérol D [or cholecalciferol] if needed) is effective and recommended for the prevention of osteoporosis.
Vitamin D insufficiency/deficiency
Based on the National Osteoporosis Foundation (NOF) Clinician's Guide to Prevention and Treatment of Osteoporosis, supplemental cholecalciferol (or Uvestérol D) may be used for the prevention or treatment of vitamin D deficiency to achieve desired serum 25(OH)D levels.
Vitamin D insufficiency/deficiency in patients with chronic kidney disease, treatment
Based on the Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease–mineral and bone disorder (CKD-MBD), vitamin D insufficiency/deficiency in patients without severe and progressive hyperparathyroidism, including chronic kidney disease stages G3 to G5 and dialysis or transplant patients, should be corrected using treatment strategies recommended for the general population, which includes repletion with Uvestérol D (or cholecalciferol).
Uvestérol D description
Uvestérol D (Vitamin D2) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond. It differs from cholecalciferol in having a double bond between C22 and C23 and a methyl group at C24. [PubChem]
Uvestérol D dosage
Uvestérol D Dosage
Generic name: Uvestérol D 1.25mg
Dosage form: capsule, liquid filled
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
THE RANGE BETWEEN THERAPEUTIC AND TOXIC DOSES IS NARROW.
Vitamin D Resistant Rickets: 12,000 to 500,000 IU units daily.
Hypoparathyroidism: 50,000 to 200,000 IU units daily concomitantly with calcium lactate 4 g, six times per day.
DOSAGE MUST BE INDIVIDUALIZED UNDER CLOSE MEDICAL SUPERVISION.
Calcium intake should be adequate. Blood calcium and phosphorus determinations must be made every 2 weeks or more frequently if necessary.
X-rays of the bones should be taken every month until condition is corrected and stabilized.
More about Uvestérol D (Uvestérol D)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 0 Reviews - Add your own review/rating
- Generic Availability
Consumer resources
- Uvestérol D
- Uvestérol D solution
- Other brands: Vitamin D2, Uvestérol D, Uvestérol D
Professional resources
- Uvestérol D (AHFS Monograph)
- Uvestérol D (FDA)
Related treatment guides
- Familial Hypophosphatemia
- Hypocalcemia
- Hypoparathyroidism
- Hypophosphatemia
- Osteomalacia
- More (4) »
Uvestérol D interactions
See also:
What other drugs will affect Uvestérol D?
increases conc of magnesium-containing antacids leading to hypermagnaesemia in patients on chronic renal dialysis. Increases digitalis glycoside conc resulting in hypercalcaemia and may precipitate cardiac arrhythmia. Increases verapamil conc resulting in atrial fibrillation. Cholestyramine and prolonged use of mineral oil decrease Uvestérol D absorption in the intestines. Thiazide diuretics may cause hypercalcaemia in hypoparathyroid patients on vit D therapy.
Food Interaction
Concomitant vit D intake with fortified foods, dietary supplements requires a limited vit D diet.
Uvestérol D side effects
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What are the possible side effects of Uvestérol D?
Applies to Uvestérol D: oral capsules and solution
Side effects include:
Possible hypervitaminosis D effects: polyuria, nocturia, polydipsia, hypercalciuria, reversible azotemia, hypertension, nephrocalcinosis, generalized vascular calcification, irreversible renal insufficiency (may be fatal), mental retardation, widespread soft tissue calcification, osteoporosis, dwarfism, vague aches, stiffness, weakness, nausea, anorexia, constipation, mild acidosis, anemia, weight loss.
Uvestérol D contraindications
See also:
What is the most important information I should know about Uvestérol D?
Hypercalcemia; malabsorption syndrome; abnormal sensitivity to the toxic effects of vitamin D; hypervitaminosis D
Note: Although the manufacturer's labeling lists use in malabsorption syndrome as contraindicated, when dosed appropriately, Uvestérol D may be used in these patients (AACE/ACE [Camacho 2016]; Dawson-Hughes 2018).
Documentation of allergenic cross-reactivity for vitamin D analogues is limited. However, because of similarities in chemical structure and/or pharmacologic actions, the possibility of cross-sensitivity cannot be ruled out with certainty.
Active ingredient matches for Uvestérol D:
Ergocalciferol in France, Vietnam.
| Unit description / dosage (Manufacturer) | Price, USD |
| Solution; Oral; Vitamin D2 / Ergocalciferol 1, 500 IU / ml | |
List of Uvestérol D substitutes (brand and generic names): | |
| Ergocalciférol | |
| Drisdol 8288 unit/ml Liquid | $ 0.48 |
| Vitamin d 400 unit softgel | $ 0.04 |
| Longs vitamin d 400 unit tablet | $ 0.03 |
| Ergocalciferol capsule, liquid filled 1.25 mg/1 (Winthrop U.S. (US)) | |
| Ergocalciferol capsule 1.25 mg/1 (Dispensing Solutions, Inc. (US)) | |
| Ergocalciferol Colonis (Malta) | |
| Ergocalciferol L.CH. (Chile) | |
| Ergocalciferol Solution | |
| Ergocalciferol Winthrop (United States) | |
| Ergokalciferolio (Lithuania) | |
| Ergokalciferolio 0.125% Sanitas (Lithuania) | |
| Ergosterol, Irradiated | |
| Galferol 2400 (Argentina) | |
| Geltabs | |
| Genevis (Chile) | |
| Infadin (Czech Republic, Slovakia) | |
| Infadin 20000 IU/1 mL x 1 Bottle 10 mL (Zentiva) | |
| Jekovit (Finland) | |
| Kalciferol SAD (Denmark) | |
| Lennon-Strong Calciferol (South Africa) | |
| Oleovitamin D, Synthetic | |
| Ostatac (Argentina) | |
| Ostelin (Argentina, Greece, Italy, Taiwan) | |
| Ostelin 250 mg x 1000's (Ifet) | |
| Ostelin 800 (Italy) | |
| Ostelin Potencia 100 (Argentina) | |
| Osto-D2 (Canada) | |
| Capsule; Oral; Vitamin D2 50, 000 units | |
| Osto-D2 capsule 50000 unit (Paladin Labs Inc (Canada)) | |
| Raquiferol (Argentina, Peru) | |
| Raquiferol D2 (Peru) | |
| Sicovit D2 (Romania) | |
| Stérogyl (France) | |
| Solution; Oral; Vitamin D2 / Ergocalciferol 20, 000 IU / ml | |
| Sterogyl (Argentina, Tunisia) | |
| Solution; Oral; Vitamin D2 / Ergocalciferol 20, 000 IU / ml (Hoechst marion roussel) | |
| Stérogyl (France) | |
| Solution; Oral; Vitamin D2 / Ergocalciferol 20, 000 IU / ml | |
| Sterovit 0.5 | |
| Steùrogyl (Vietnam) | |
| Tanvimil D (Argentina) | |
| Uvesterol-D | |
| Vitamin D Ergocalciferol | |
| Vitamin D Slovakofarma (Czech Republic, Lithuania, Slovakia) | |
| Vitamin D2 | |
| Vitamina D Richmond (Argentina) | |
| Vitamina D2 Salf (Italy) | |
See 112 substitutes for Uvestérol D | |
References
- DailyMed. "ERGOCALCIFEROL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "ergocalciferol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "ergocalciferol". http://www.drugbank.ca/drugs/DB00153 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Uvestérol D are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Uvestérol D. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
