What is Gentrobex?
Treating surface eye infections caused by certain bacteria.
Gentrobex is a topical antibiotic. It works by slowing the growth of, or killing, sensitive bacteria.
Gentrobex indications
Primary skin infections: Impetigo contagiosa, superficial folliculitis, ecthyma, furunculosis, sycosis barbae, and pyoderma gangrenosum. Secondary skin infections: Infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis, infected contact dermatitis (including poison ivy), infected excoriations, and bacterial superinfections of fungal or viral infections. Please Note: Gentrobex is a bactericidal agent that is not effective against viruses or fungi in skin infections. It is useful in the treatment of infected skin cysts and certain other skin abscesses when preceded by incision and drainage to permit adequate contact between the antibiotic and the infecting bacteria. Good results have been obtained in the treatment of infected stasis and other skin ulcers, infected superficial burns, paronychia, infected insect bites and stings, infected lacerations and abrasions, and wounds from minor surgery. Patients sensitive to neomycin can be treated with Gentrobex, although regular observation of patients sensitive to topical antibiotics is advisable when such patients are treated with any topical antibiotic. Gentrobex Cream USP, 0.1% is recommended for wet, oozing primary infections, and greasy, secondary infections, such as pustular acne or infected seborrheic dermatitis. Gentrobex ointment helps retain moisture and has been useful in infection on dry eczematous or psoriatic skin. If a water-washable preparation is desired, the cream is preferable. Gentrobex Cream USP, 0.1% has been used successfully in infants over one year of age, as well as in adults and children.
How should I use Gentrobex?
Use Gentrobex as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Gentrobex may be used around the eye or in the eye, as directed by your doctor. To use Gentrobex in the eye, first, wash your hands. Using your index finger, pull the lower eyelid away from your eye to form a pouch. Squeeze a thin strip of ointment into the pouch. After using Gentrobex, gently close your eyes for 1 to 2 minutes. Wash your hands to remove any medicine that may be on them. Wipe the applicator tip with a clean, dry tissue.
- To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
- Do not wear contact lenses while you are using Gentrobex. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.
- Gentrobex is only for the eye. Do not get it in your nose or mouth.
- To clear up your infection completely, use Gentrobex for the full course of treatment. Keep using it even if you feel better in a few days.
- Using Gentrobex at the same times each day will help you to remember to use it.
- If you miss a dose of Gentrobex, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Gentrobex.
Uses of Gentrobex in details
This medication is used to treat minor skin infections (such as impetigo, folliculitis) or minor infections related to some skin conditions (such as eczema, psoriasis, minor burns/cuts/wounds). Gentrobex works by stopping the growth of certain bacteria. It belongs to a class of drugs known as aminoglycoside antibiotics.
This antibiotic only treats bacterial infections. It will not work for virus or fungus infections. Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.
How to use Gentrobex topical
This medication is for use on the skin only.
Wash your hands before using. Clean and dry the affected area as directed. If you are treating impetigo, remove any dried, crusty skin to increase contact between the antibiotic and the infected area. Then gently apply a small amount of medication in a thin layer as directed by your doctor, usually 3 to 4 times a day. You may cover the area with a sterile gauze bandage if so directed. Keep the infected area clean. Wash your hands after use, unless you are using this product to treat the hands.
Avoid getting this medication in your eyes, nose, or mouth. If this occurs, wipe off the medication and rinse thoroughly with water.
Dosage and length of treatment is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day. Do not apply large amounts of this medication, use it more often, or use it for longer than prescribed. Your condition will not improve any faster, and your risk of side effects may increase.
Continue to use this medication for the full length of treatment prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.
Tell your doctor if your skin infection persists or if it worsens.
Gentrobex description
Gentrobex also contains the following ingredients: Methyl paraben 1.8 mg, propyl paraben 0.2 mg, sodium bisulfite 3.2 mg, disodium ethylenediaminetetraacetate 0.1 mg and water for injection.
Gentrobex injection is a sterile solution of Gentrobex water for injection. It contains the equivalent of not less than 90% and not more than 125% of the labeled amount of Gentrobex. It may contain suitable buffers, preservatives, sequestering agents, unless it is intended for intrathecal use, in which case it contains only suitable tonicity agents.
Gentrobex dosage
A small amount of Gentrobex Cream USP, 0.1% should be applied gently to lesions three or four times a day. The area treated may be covered with a gauze dressing if desired. In impetigo contagiosa, the crusts should be removed before application of Gentrobex Cream USP, 0.1% to permit maximum contact between the antibiotic and the infection. Care should be exercised to avoid further contamination of the infected skin. Infected stasis ulcers have responded well to Gentrobex under gelatin packing.
Gentrobex interactions
See also:
What other drugs will affect Gentrobex?
The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.
To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.
Some products that may interact with this drug include: aminoglycoside antibiotics given by injection (such as amikacin, Gentrobex, tobramycin).
This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.
Gentrobex side effects
See also:
What are the possible side effects of Gentrobex?
In patients with dermatoses treated with Gentrobex, irritation (erythema and pruritus) that did not usually require discontinuance of treatment has been reported in a small percentage of cases. There was no evidence of irritation or sensitization, however, in any of these patients patch-tested subsequently with Gentrobex on normal skin. Possible photosensitization has been reported in several patients but could not be elicited in these patients by reapplication of Gentrobex followed by exposure to ultraviolet radiation.
Gentrobex contraindications
See also:
What is the most important information I should know about Gentrobex?
Gentrobex Sterile Ophthalmic Solution is contraindicated in patients with known hypersensitivity to any of the components.
Active ingredient matches for Gentrobex:
Gentamicin sulfate in Philippines.
| Unit description / dosage (Manufacturer) | Price, USD |
| Gentrobex 40 mg/1 mL x 10's | |
List of Gentrobex substitutes (brand and generic names): | |
| Gentamycin Ophth Oint (Taiwan) | |
| Gentamycin Ophth Oint 3 mg/1 g x 5 g | |
| Gentamycin Ophth Soln (Taiwan) | |
| Gentamycin Ophth Soln 3 mg/1 mL x 3 mL | |
| Gentamycin Ophth Soln 3 mg/1 mL x 5 mL | |
| Gentamycin Ophthalmic (Taiwan) | |
| Gentamycin Ophthalmic / Wu-Fu 3 mg/1 mL x 5 mL | |
| Gentamycin Sulfate Shandong (Vietnam) | |
| Gentamycin Sulfate Shandong 80 mg/2 mL x 10 tube 2mL | |
| Gentamycine 10% | |
| Gentamycine Llorenté | |
| Gentamytrex Drops | |
| Gentamytrex Oint | |
| Gentamytrex Ophtiole (Taiwan) | |
| Gentamytrex Ophtiole 5 mg/1 mL x 5 mL | |
| Gentamytrex Ophtiole 5 mg/1 mL x 5 mL x 1's | |
| Gentazor 40 | |
| Gentazor 80 | |
| Gentosyl | |
| Getasin (Turkey) | |
| Grammicin Ear Drops (Thailand) | |
| Grammicin Eye Drops (Thailand) | |
| I-Gent | |
| Konigen (Indonesia) | |
| Migentax (Philippines) | |
| Migentax 40 mg/1 mL x 2 mL x 10's (Geofman) | |
| Miramycin/Miramycin Injection (Malaysia) | |
| Negamycin 40 | |
| Negamycin 80 | |
| Obogen (Philippines) | |
| Obogen / amp 40 mg/1 mL x 2 mL x 10's (Oboi) | |
| Opthagen (Philippines) | |
| Opthagen 0.3 % x 5 mL (Pascual) | |
| Ottogenta Cream (Indonesia) | |
| Ottogenta Cream 0.1 % x 5 g x 1's | $ 0.66 |
| Phil Pharmawealth/Karnataka Gentamicin (Philippines) | |
| Phil Pharmawealth/Karnataka Gentamicin / vial 40 mg/1 mL x 2 mL x 50's | |
| Phil Pharmawealth/Korea United Gentamicin (Philippines) | |
| Refobacin Bone Cement R (Thailand) | |
| Refobacin Bone Cement R 40 g x 2's (Biomet) | |
| Refobacin Bone Cement R 20 mL x 2's (Biomet) | |
| Ridhay (Vietnam) | |
| Ridhay 0.3 % w/v x 1 Bottle 10 mL | |
| Rotexmedica Gentamicin (Vietnam) | |
| Rotexmedica Gentamicin 1 tube | |
| Sagestam Ear Drops (Indonesia) | |
| Sagestam Ear Drops 3 mg/1 mL x 5 mL x 1's (Sanbe Vision) | $ 2.02 |
| Sagestam Eye Drops (Indonesia) | |
| Sagestam Eye Drops 3 mg/1 mL x 5 mL x 1's | $ 2.02 |
| Sagestam Eye Drops/Ointment (Indonesia) | |
| Salticin Cream (Indonesia) | |
| Salticin Cream 1 mg/1 g x 5 g | $ 1.18 |
| Sannogen (Philippines) | |
| Sterisol fermentmycin (South Africa) | |
| T P Gentamicin Sulfate (Vietnam) | |
| T P Gentamicin Sulfate 80 mg/2 mL x 10 tube | |
| T P Gentamicin Sulfate 80 mg/2 mL x 50 tube | |
| Topigen Eye Drops (Philippines) | |
| Topigen Eye Drops 3 mg/1 mL x 5 mL x 1's | $ 4.36 |
See 126 substitutes for Gentrobex | |
References
- DailyMed. "GENTAMICIN SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "gentamicin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "gentamicin". http://www.drugbank.ca/drugs/DB00798 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Gentrobex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Gentrobex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yetConsumer reported age
No survey data has been collected yetConsumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
