Misovan indications
For use Max Pidek Pharmaceuticals as monotherapy and in combination with clavulanic acid: an infectious-inflammatory diseases caused by susceptible microorganisms, including bronchitis, pneumonia, tonsillitis, pyelonephritis, urethritis, infections of the gastrointestinal tract, gynecological infections, infections of the skin and soft tissue, listeria, leptospirosis, gonorrhea.
For use Max Pidek Pharmaceuticals in combination with metronidazole: chronic gastritis in acute, peptic ulcer and duodenal ulcer in acute, associated with Helicobacter Pylori.
Uses of Misovan in details
Misovan is used to treat certain diseases of the respiratory tract and to relieve cough associated with thickened mucous.
Misovan description
Each retard capsule contains Ambroxol 75 mg.
Each tablet contains Ambroxol 30 mg.
Each 5 mL of syrup contains Ambroxol 15 or 30 mg.
Each mL of syrup (infant drops) contains Ambroxol 6 mg.
Misovan is trans-4-[(2-amino-3,5-dibromo-benzyl)amino] cyclohexanol hydrochloride.
It also contains the following excipients: Retard Capsules: Crospovidone collidon CL, carnauba wax, stearyl alcohol, magnesium stearate.
Tablets: Lactose, maize starch, colloidal silica, magnesium stearate.
Syrup: Purified water, sorbitol liquid, glycerol 85%, woodberry aroma (15 mg only), strawberry aroma (30 mg only), hydroxyethylcellulose, benzoic acid, acesulfame potassium, vanilla aroma.
Infant Drops: Hydroxyethylcellulose, sorbitol solution, glycerol 85%, sodium saccharin, pharma flavors, menthol, benzoic acid, propylene glycol.
Misovan dosage
Sustained-Release Capsule: Adults and Children >12 years: 1 cap once daily after meal with plenty of liquid (sufficient supply of liquid supports the expectorant effect of Misovan).
Misovan SR capsule is not suitable for children <12 years.
Tablet: Adults and Children >12 years: 1 tab thrice daily for the first 2-3 days and then 1 tab twice daily or ½ tab thrice daily. Children 6-12 years: ½ tab 2-3 times a day.
Syrup: Adults and Children >12 years: 10 mL thrice daily during the first 2-3 days, them 10 mL twice daily or 5 mL thrice daily. Children 6-12 years: 5 mL 2-3 times a day; 2-5 years: 2.5 mL 3 times a day; <2 years: 2.5 mL 2 times a day.
DS Syrup: Adults and Children >12 years: 5 mL thrice daily for 2-3 days then 5 mL twice daily for 2.5 mL thrice daily. Children 6-12 years: 2.5 mL 2-3 times a day.
Infant Drops: Children 13-24 months: 1.25 mL twice a day; 7-12 months: 1 mL twice a day; ≤6 months: 0.5 mL twice a day.
Misovan interactions
Amoxicillin may decrease the effectiveness of contraceptives for oral administration.
With the simultaneous use of Max Pidek Pharmaceuticals with bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin) appears synergies; with bacteriostatic antibiotic (including macrolides, chloramphenicol, lincosamides, tetracyclines, sulphonamide) - antagonism.
Amoxicillin increases the effects of indirect anticoagulants inhibiting intestinal microflora, reduces the synthesis of vitamin K and prothrombin index.
Amoxicillin reduces the effect of drugs, in the process of metabolism that produce PABA.
Probenecid, diuretics, allopurinol, phenylbutazone, NSAIDs decrease the tubular secretion of amoxicillin, which can be accompanied by an increase in its concentration in blood plasma.
Antacids, glucosamine, laxatives, aminoglycosides, slow down and reduce, and ascorbic acid increases the absorption of amoxicillin.
With the combined use of amoxicillin and clavulanic acid pharmacokinetics of both components unchanged.
Misovan side effects
Allergic reactions: urticaria, erythema, edema Quincke, rhinitis, conjunctivitis, rarely - fever, joint pain, eosinophilia, in rare cases - anaphylactic shock.
Side effects associated with chemotherapy effect: possible development of super-infection (particularly in patients with chronic diseases or low resistance of the organism).
With prolonged use at high doses: dizziness, ataxia, confusion, depression, peripheral neuropathy, seizures.
Mostly when Max Pidek Pharmaceuticals used in combination with metronidazole: nausea, vomiting, anorexia, diarrhea, constipation, epigastric pain, glossitis, stomatitis; rarely - hepatitis, pseudomembranous colitis, allergic reactions (urticaria, angioedema), interstitial nephritis, a violation of hematopoiesis.
Mostly when Max Pidek Pharmaceuticals used in combination with clavulanic acid: cholestatic jaundice, hepatitis, rarely - erythema multiforme, toxic epidermal necrolysis, exfoliative dermatitis.
Misovan contraindications
Hypersensitivity to Misovan or to any other excipients of Misovan.
In case of rare hereditary conditions that may be incompatible with an excipient of Misovan, the use of Misovan is contraindicated.
Active ingredient matches for Misovan:
Ambroxol in Thailand.
Ambroxol HCl in Thailand.
Ambroxol hydrochloride in Thailand.
| Unit description / dosage (Manufacturer) | Price, USD |
| Misovan 30 mg x 500's | |
| Misovan 30 mg/5 mL x 60 mL | |
| Misovan 30 mg/5 mL x 3.8 L | |
| Misovan syr 30 mg/5 mL 60 mL x 1's (T. O. Chemicals) | |
| Misovan syr 30 mg/5 mL 3800 mL x 1's (T. O. Chemicals) | |
| Misovan tab 30 mg 500's (T. O. Chemicals) | |
List of Misovan substitutes (brand and generic names): | |
| Mintamox (Chile) | |
| Mitasolbide (Japan) | |
| Mokotam (Taiwan) | |
| Mokotam 30 mg x 1000's | |
| Molapect (Indonesia) | |
| Molapect 30 mg x 10 x 10's (Molex ayus) | $ 5.46 |
| Molapect 15 mg/5 mL x 60 mL x 1's (Molex ayus) | $ 0.81 |
| Molapect 30 mg/5 mL x 60 mL (Molex ayus) | $ 1.09 |
| Mosapec (Indonesia) | |
| Motosol (Spain) | |
| Motosol Retard (Spain) | |
| Movent (Thailand) | |
| Movent 30 mg x 500's (Community Pharm PCL) | |
| Movent 30 mg x 50 x 10's (Community Pharm PCL) | |
| Movent 30 mg/5 mL x 60 mL (Community Pharm PCL) | |
| Movent syr 30 mg/5 mL 60 mL x 1's (Community Pharm PCL) | |
| Movent tab 30 mg 50 x 10's (Community Pharm PCL) | |
| Movent tab 30 mg 500's (Community Pharm PCL) | |
| Mubroxol (Taiwan) | |
| Mubroxol 30 mg x 25 x 10's | |
| Mubroxol 30 mg x 1000's | |
| Mubroxol 30 mg/5 mL x 60 mL x 12's | |
| Mubroxol 30 mg x 100 x 10's | |
| Mucabrox (Switzerland) | |
| Solution; Inhalation; Ambroxol Hydrochloride 7.5 mg / ml (Streuli) | |
| Tablet; Oral; Ambroxol Hydrochloride 30 mg (Streuli) | |
| Mucaryl- AX | |
| Mucaryl- AX Ambroxol 15mg, Terbutaline1.25mg, guiaphenesin 50 EXP | |
| Mucera (Indonesia) | |
| Mucera 30 mg x 10 x 10's (Otto) | $ 8.18 |
| Mucera 30 mg/5 mL x 60 mL x 1's (Otto) | $ 2.17 |
| Mucera 15 mg/5 mL x 60 mL x 1's (Otto) | $ 1.80 |
| Mucera 15 mg/1 mL x 15 mL x 1's (Otto) | $ 3.10 |
| Mucibron (Brazil, Dominican Republic, Spain) | |
| Mucifar (Dominican Republic) | |
| Muco Patar (Thailand) | |
| Muco Patar 30 mg x 500's | |
| Muco SR (Egypt) | |
| Muco-Aspecton (Germany) | |
| Drops; Oral; Ambroxol Hydrochloride (Krewel) | |
| Syrup; Oral; Ambroxol Hydrochloride (Krewel) | |
| Tablet; Oral; Ambroxol Hydrochloride (Krewel) | |
| Muco-Fips (Germany) | |
| Muco-Tablinen (Germany) | |
| Mucoangin (Austria, Belgium, Bulgaria, Denmark, Germany, Hungary, Luxembourg, Mexico, Netherlands, Poland, Romania, Sweden, Venezuela) | |
| Pastilles; Oral; Ambroxol Hydrochloride 20 mg (Boehringer Ingelheim) | |
| Mucoangin loz 20 mg / mint-flavored, sugar-free 12's (Boehringer Ingelheim) | $ 0.59 |
| Mucoangin 2.5mg (Luxembourg) | |
| Mucoangin 20mg (Austria, Hungary, Luxembourg) | |
| Mucoaricodil (Italy) | |
| Mucoastomari (Japan) | |
| Mucobar-S Syrup (India) | |
| Mucobar-S Syrup Ambroxol 30 mg, Guaiphenesin100 mg, Salbutamol 2 mg, Menthol 1 mg. SYR / 100ml (Symbiotic) | $ 0.54 |
See 3211 substitutes for Misovan | |
References
- PubChem. "ambroxol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "ambroxol". http://www.drugbank.ca/drugs/DB06742 (accessed September 17, 2018).
- MeSH. "Expectorants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Misovan are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Misovan. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
