Pp-500 Uses

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Pp-500 indications

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To avoid and correct vitamin deficiency, which may

result from an imbalanced or special diet, impaired

absorption, anorexia, slimming, pathological intestinal

flora, debilitating disease or therapy with drugs acting

as vitamin antagonists.

Pp-500 syrup meets the increased vitamin requirements

during periods of intensive growth, and as a dietary

supplement in premature and newborn infants.

Uses of Pp-500 in details

Pp-500 is used to treat vitamin B3 deficiency and inflammatory skin diseases like acne and pellagra.

Pp-500 description

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. [PubChem]

Pp-500 dosage

Oral

Treatment and prophylaxis of nicotinic acid deficiency

Adult: Up to 500 mg daily in divided doses. May also be given via IM or by slow IV inj.

Topical/Cutaneous

Mild to moderate inflammatory acne

Adult: As a 4% gel: Apply bid, reduce to once daily or on alternate days if irritation occurs.

Pp-500 interactions

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Pp-500: The clearance of primidone and carbamazepine may be reduced with the concomitant use of Pp-500.

Zinc Oxide: The absorption of quinolones or tetracycline may be decreased with the concomitant use of zinc.

Cupric Oxide: Concomitant use of penicillamine and copper can cause decreased absorption of both substances.

Pp-500 side effects

Allergic sensitization has been reported rarely following oral and parenteral administration of Folic Acid.

At recommended doses, Pp-500 is expected to be well tolerated. Gastrointestinal distress such as nausea or vomiting have been associated with the administration of Pp-500 or zinc at doses greater than the recommended dose of Pp-500

Pp-500: Dizziness, headache, hyperglycemia, nausea, vomiting, diarrhea, elevations in liver function tests, hepatotoxicity, blurred vision, flushing, rash.

Pp-500 contraindications

contraindicated in patients with hypersensitivity to any of its components.

Active ingredient matches for Pp-500:

Nicotinamide in Vietnam.


Unit description / dosage (Manufacturer)Price, USD
PP-500 500 mg x 30 Tablet

List of Pp-500 substitutes (brand and generic names):

Nisderm Skin 20 gm Ointment (Neiss Labs Pvt. Ltd.)$ 0.72
NU B12 Kit (Sanjeevani Bio-Tech (P) Ltd)$ 0.66
Nurosal Forte Tablet (Salvo Healthcare Pvt Ltd)$ 0.05
Nutrozyme Tablet (Cipla Limited)$ 0.02
O Vit Inj Injection (Oscar Remedies Pvt. Ltd.)$ 0.10
Shalvit 120 ml Syrup (Shalina Laboratories Ltd)$ 0.01
Sovit 200 ml Syrup (Diamond Drugs Pvt Ltd)$ 0.02
Sovit 100 ml Syrup (Diamond Drugs Pvt Ltd)$ 0.02
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Synokem 200 ml Syrup (Synokem Pharmaceuticals Ltd)$ 0.05
Therabine Inj Injection (Parex Phamaceuticals Pvt. Ltd.)$ 0.25
Therabine 200 mg Injection (Parex Phamaceuticals Pvt. Ltd.)$ 0.03
Threptin Granules (Raptakos Brett & Co. Ltd.)$ 2.65
Tobal Plus Inj Injection (Injecto Capta Pvt. Ltd.)$ 0.59
TOBAL PLUS inj 2ml (Injecto Capta Pvt. Ltd.)$ 0.59
Truzyme Tablet Capsule (Devbhoomi Pharmaceuticals)$ 0.03
Unienzyme C MPS Tablet (Unichem Laboratories Ltd)$ 0.02
Unienzyme Tablet (Unichem Laboratories Ltd.)$ 0.02
VBC 12 Inj Injection (Neon Laboratories Ltd)$ 0.07
Visoliv 60 ml Syrup (Vision Biotech)$ 0.09
Vitamin PP MKP 500 mg x 1 Bottle 30 Tablet
Vitamin PP Pharmedic 500 mg x 10 Blister x 10 Tablet
Tablet; Oral; Vitamin B3 / Nicotinamide 200 mg
Tablet; Oral; Vitamin B3 / Nicotinamide 50 mg
Vitamx 5 ml Drop (Hamax Pharmaceuticals)$ 0.05
Vivclind N Skin 15 gm Gel (Vivia (Biochemix Healthcare Pvt Ltd))$ 0.84
Vize Capsule (Oasis Remedies)$ 0.04
Xoplex 200 ml Syrup (Quixotic Pharma (P) Ltd.)$ 0.02
Xoplex L 200 ml Syrup (Quixotic Pharma (P) Ltd.)$ 0.02

References

  1. DailyMed. "ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PHYTONADIONE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN 5'-PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "nicotinamide". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "nicotinamide". http://www.drugbank.ca/drugs/DB02701 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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