To avoid and correct vitamin deficiency, which may
result from an imbalanced or special diet, impaired
absorption, anorexia, slimming, pathological intestinal
flora, debilitating disease or therapy with drugs acting
as vitamin antagonists.
Xoplex syrup meets the increased vitamin requirements
during periods of intensive growth, and as a dietary
supplement in premature and newborn infants.
Xoplex is used to treat vitamin B3 deficiency and inflammatory skin diseases like acne and pellagra.
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. [PubChem]
Treatment and prophylaxis of nicotinic acid deficiency
Adult: Up to 500 mg daily in divided doses. May also be given via IM or by slow IV inj.
Mild to moderate inflammatory acne
Adult: As a 4% gel: Apply bid, reduce to once daily or on alternate days if irritation occurs.
Xoplex: The clearance of primidone and carbamazepine may be reduced with the concomitant use of Xoplex.
Zinc Oxide: The absorption of quinolones or tetracycline may be decreased with the concomitant use of zinc.
Cupric Oxide: Concomitant use of penicillamine and copper can cause decreased absorption of both substances.
Allergic sensitization has been reported rarely following oral and parenteral administration of Folic Acid.
At recommended doses, Xoplex is expected to be well tolerated. Gastrointestinal distress such as nausea or vomiting have been associated with the administration of Xoplex or zinc at doses greater than the recommended dose of Xoplex
Xoplex: Dizziness, headache, hyperglycemia, nausea, vomiting, diarrhea, elevations in liver function tests, hepatotoxicity, blurred vision, flushing, rash.
contraindicated in patients with hypersensitivity to any of its components.
|Unit description / dosage (Manufacturer)||Price, USD|
|Xoplex 200 ml Syrup||$ 0.02|
List of Xoplex substitutes (brand and generic names):
|Nicotinsäureamid Jenapharm (Germany)|
|Nisderm Skin 20 gm Ointment (Neiss Labs Pvt. Ltd.)||$ 0.95|
|NU B12 Kit|
|NU B12 Kit (Sanjeevani Bio-Tech (P) Ltd)||$ 0.87|
|Nurosal Forte Tablet|
|Nurosal Forte Tablet (Salvo Healthcare Pvt Ltd)||$ 0.06|
|Nutrozyme Tablet (Cipla Limited)||$ 0.02|
|O Vit Inj Injection (Oscar Remedies Pvt. Ltd.)||$ 0.13|
|PP-500 500 mg x 30 Tablet|
|Pu Fu Lin (China)|
|Shalvit 120 ml Syrup (Shalina Laboratories Ltd)||$ 0.02|
|Sovit 200 ml Syrup (Diamond Drugs Pvt Ltd)||$ 0.02|
|Sovit 100 ml Syrup (Diamond Drugs Pvt Ltd)||$ 0.03|
|Synokem 200 ml Syrup (Synokem Pharmaceuticals Ltd)||$ 0.06|
|Therabine Inj Injection (Parex Phamaceuticals Pvt. Ltd.)||$ 0.33|
|Therabine 200 mg Injection (Parex Phamaceuticals Pvt. Ltd.)||$ 0.04|
|Threptin Granules (Raptakos Brett & Co. Ltd.)||$ 3.49|
|Tobal Plus (India)|
|Tobal Plus Inj Injection (Injecto Capta Pvt. Ltd.)||$ 0.78|
|TOBAL PLUS inj 2ml (Injecto Capta Pvt. Ltd.)||$ 0.78|
|Truzyme Tablet Capsule|
|Truzyme Tablet Capsule (Devbhoomi Pharmaceuticals)||$ 0.04|
|Ucemine PP (Belgium, Luxembourg)|
|Ucemine PP 100mg (Luxembourg)|
|Unienzyme C MPS Tablet|
|Unienzyme C MPS Tablet (Unichem Laboratories Ltd)||$ 0.02|
|Unienzyme Tablet (Unichem Laboratories Ltd.)||$ 0.03|
|VBC 12 Inj Injection (Neon Laboratories Ltd)||$ 0.09|
|Visoliv 60 ml Syrup (Vision Biotech)||$ 0.12|
|Vitamin PP (Lithuania)|
|Vitamin PP MKP (Vietnam)|
|Vitamin PP MKP 500 mg x 1 Bottle 30 Tablet|
|Vitamin PP Pharmedic (Vietnam)|
|Vitamin PP Pharmedic 500 mg x 10 Blister x 10 Tablet|
|Vitamina PP Angelini (Italy)|
|Vitamine PP Aguettant (France)|
|Vitaminum PP (Poland)|
|Tablet; Oral; Vitamin B3 / Nicotinamide 200 mg|
|Tablet; Oral; Vitamin B3 / Nicotinamide 50 mg|
|Vitaminum PP GSK (Poland)|
|Vitaminum PP Omega Pharma (Poland)|
|Vitaminum PP Polfarmex (Poland)|
|Vitaminum PP Teva (Poland)|
|Vitamx 5 ml Drop (Hamax Pharmaceuticals)||$ 0.07|
|Vivclind N Skin 15 gm Gel (Vivia (Biochemix Healthcare Pvt Ltd))||$ 1.11|
|Vize Capsule (Oasis Remedies)||$ 0.06|
|Xoplex L 200 ml Syrup (Quixotic Pharma (P) Ltd.)||$ 0.02|
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Information checked by Dr. Sachin Kumar, MD Pharmacology