What is Pyrantin?
Pyrantin belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.
Pyrantin is used to treat pinworms (enterobiasis; oxyuriasis).
Pyrantin may also be used for other worm infections as determined by your doctor.
Pyrantin works by paralyzing the worms. They are then passed in the stool.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Pyrantin is used in certain patients with the following medical condition:
- Common roundworm infection
- Hookworm infection
- More than one worm infection at a time
For patients taking Pyrantin for hookworm infection :
- Anemia (iron-poor blood) may occur in patients with hookworm infections. Therefore, your doctor may want you to take iron supplements to help clear up the anemia. If so, it is important to take iron every day while you are being treated for hookworms. Do not miss any doses. Your doctor may also want you to keep taking iron supplements for up to 6 months after you stop taking Pyrantin. If you have any questions about this, check with your doctor.
Pyrantin indications
Oral
Single or mixed infections due to susceptible worms
Adult: 10 mg/kg as a single dose.
Child: 10 mg/kg as a single dose.
Oral
Ascariasis
Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr.
Oral
Necatoriasis
Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days.
Oral
Enterobiasis
Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose.
Oral
Trichinosis
Adult: 10 mg/kg daily for 5 days.
How should I use Pyrantin?
Use Pyrantin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Pyrantin may be taken on an empty stomach or with food, milk, or juice.
- Shake well before using a dose of Pyrantin.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Wear tight underwear both day and night while taking Pyrantin.
- Pyrantin is usually prescribed as a single dose.
- Only one dose of Pyrantin is required. If you forget to take Pyrantin, take it as soon as you remember.
Ask your health care provider any questions you may have about how to use Pyrantin.
Pyrantin description
Pyrantin is an antinematodal thiophene
Pyrantin dosage
Pyrantin Dosage
Applies to the following strength(s): 144 mg/mL; 180 mg; 50 mg/mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
- Enterobiasis
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Trichostrongylosis
- Moniliformis Infection
Usual Pediatric Dose for:
- Enterobiasis
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Trichostrongylosis
- Moniliformis Infection
Additional dosage information:
- Renal Dose Adjustments
- Liver Dose Adjustments
- Dose Adjustments
- Precautions
- Dialysis
- Other Comments
Usual Adult Dose for Enterobiasis
11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.
Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)
11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.
Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)
11 mg/kg base (maximum 1 g) orally daily for 3 days.
Usual Adult Dose for Ascariasis
11 mg/kg base (maximum 1 g) orally once.
Usual Adult Dose for Trichostrongylosis
11 mg/kg base (maximum 1 g) orally once.
Usual Adult Dose for Moniliformis Infection
11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.
Usual Pediatric Dose for Enterobiasis
>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.
Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)
>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.
Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)
>=2 years: 11 mg/kg base (maximum 1 g) orally daily for 3 days.
Usual Pediatric Dose for Ascariasis
>=2 years: 11 mg/kg base (maximum 1 g) orally once.
Usual Pediatric Dose for Trichostrongylosis
>=2 years: 11 mg/kg base (maximum 1 g) orally once.
Usual Pediatric Dose for Moniliformis Infection
>=2 years: 11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Pyrantin is contraindicated in patients with hepatic disease.
Dose Adjustments
In the treatment of ascariasis, Pyrantin may be used only if it has been determined that the worm load will not worsen obstruction.
Precautions
Pyrantin is contraindicated in patients with hepatic disease.
When one individual in a household has pinworms, the entire household should be treated unless otherwise advised. Pinworm infections are easily transmitted to others in the same household.
Pyrantin should be used with caution in patients with severe malnutrition or anemia. Supportive therapy is recommended for anemic, dehydrated, or malnourished patients prior to administration of the drug.
Other medications are known to antagonize the anthelmintic effect of Pyrantin. Patients should be advised to consult with their physician before initiating any drug therapy while receiving Pyrantin.
Dialysis
Data not available
Other Comments
The dose should be taken as a single oral dose. It may be taken alone or with milk or fruit juice.
Pyrantin 2.9 g is approximately equivalent to 1 g of Pyrantin (base).
More about Pyrantin
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- En Espanol
- 4 Reviews - Add your own review/rating
Consumer resources
- Pyrantin chewable tablets
- Pyrantin
- Pyrantin suspension
- Pyrantin
- Pyrantin (Advanced Reading)
- Other brands: Pin-X, Pinworm Medicine, Reese's Pinworm Medicine, Pinworm Caplets, More (2) »
Professional resources
- Pyrantin (AHFS Monograph)
Related treatment guides
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Enterobiasis
- Moniliformis Infection
- More (1) »
Pyrantin interactions
See also:
What other drugs will affect Pyrantin?
• Dexamethasone
Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.
• Praziquantel
• Cimetidine
Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12). Albendazole sulfoxide plasma concentrations were unchanged 4 hours after dosing.
• Theophylline
The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of albendazole (400 mg) in 6 healthy subjects.
Pyrantin side effects
See also:
What are the possible side effects of Pyrantin?
Applies to Pyrantin: oral suspension, oral tablet, oral tablet chewable
In addition to its needed effects, some unwanted effects may be caused by Pyrantin (the active ingredient contained in Pyrantin). In the event that any of these side effects do occur, they may require medical attention.
Severity: Moderate
If any of the following side effects occur while taking Pyrantin, check with your doctor or nurse as soon as possible:
Rare
- Skin rash
Minor Side Effects
Some of the side effects that can occur with Pyrantin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Less common:
- Abdominal or stomach cramps or pain
- diarrhea
- dizziness
- drowsiness
- headache
- irritability
- loss of appetite
- nausea or vomiting
- trouble in sleeping
Pyrantin contraindications
See also:
What is the most important information I should know about Pyrantin?
This medicine is contraindicated in patients with known hypersensitivity to the benzimidazole class of compounds or any components of this medicine.
Active ingredient matches for Pyrantin:
Pyrantel in Sri Lanka, Tunisia.
Paroxetine in Malta.
Pyrantel embonate in Hong Kong.
List of Pyrantin substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Pyrantesan (Poland) | |
| Pyrantrin (Hong Kong) | |
| Pyrantverm (Poland) | |
| Pyrapam (Thailand) | |
| Pyrapam 125 mg x 1, 000's (General Drugs House) | |
| Pyrapam 50 mg/1 mL x 10 mL (General Drugs House) | |
| Pyrapam oral susp 50 mg/mL 10 mL x 1's (General Drugs House) | |
| Pyrapam tab 125 mg 1000's (General Drugs House) | |
| Pyratape (Ireland, United Kingdom) | |
| Pyraverm 125 | |
| Pyraverm 250 | |
| Pyrequan | |
| Pyteldon (Thailand) | |
| Pyteldon 125 mg x 100's | |
| Pyteldon 250 mg/5 mL x 10 mL x 12's | |
| Q.T. Ban Tech (United States) | |
| Quantrel (Colombia, Peru, Philippines) | |
| Quantrel 10 mL (Johnson & Johnson) | $ 3.57 |
| Quantrel oral susp 10 mL x 1's (Johnson & Johnson) | $ 3.57 |
| ratio-Paroxetine (Canada) | |
| Tablet; Oral; Paroxetine Hydrochloride 10 mg | |
| Tablet; Oral; Paroxetine Hydrochloride 20 mg | |
| Tablet; Oral; Paroxetine Hydrochloride 30 mg | |
| Tablets; Oral; Paroxetine Hydrochloride 10 mg | |
| Tablets; Oral; Paroxetine Hydrochloride 20 mg | |
| Tablets; Oral; Paroxetine Hydrochloride 30 mg | |
| Ratio-paroxetine tablet 10 mg (Ratiopharm Inc Division Of Teva Canada Limited (Canada)) | |
| Ratio-paroxetine tablet 20 mg (Ratiopharm Inc Division Of Teva Canada Limited (Canada)) | |
| Ratio-paroxetine tablet 30 mg (Ratiopharm Inc Division Of Teva Canada Limited (Canada)) | |
| RAXIT (India) | |
| RAXIT Capsule/ Tablet / 10mg / 10 units (Ranbaxy (Solus)) | $ 0.84 |
| RAXIT Capsule/ Tablet / 20mg / 10 units (Ranbaxy (Solus)) | $ 1.20 |
| RAXIT Capsule/ Tablet / 30mg / 10 units (Ranbaxy (Solus)) | $ 1.69 |
| Raxit 10mg TAB / 10 (Ranbaxy (Solus)) | $ 0.87 |
| Raxit 20mg TAB / 10 (Ranbaxy (Solus)) | $ 1.25 |
| 10 mg x 10's (Ranbaxy (Solus)) | $ 0.87 |
| 20 mg x 10's (Ranbaxy (Solus)) | $ 1.25 |
| RAXIT 10MG TABLET 1 strip / 10 tablets each (Ranbaxy (Solus)) | $ 0.84 |
| RAXIT 20MG TABLET 1 strip / 10 tablets each (Ranbaxy (Solus)) | $ 1.20 |
| RAXIT tab 10 mg x 10's (Ranbaxy (Solus)) | $ 0.87 |
| RAXIT tab 20 mg x 10's (Ranbaxy (Solus)) | $ 1.25 |
| Raxit 10mg TAB / 10 (Ranbaxy (Solus)) | $ 0.87 |
| Raxit 20mg TAB / 10 (Ranbaxy (Solus)) | $ 1.25 |
| Raxit 10mg Tablet (Ranbaxy (Solus)) | $ 0.08 |
| Raxit 20mg Tablet (Ranbaxy (Solus)) | $ 0.12 |
| Reese’s Pinworm | |
| Reese's Pinworm (United States) | |
See 1913 substitutes for Pyrantin | |
References
- DailyMed. "PAROXETINE MESYLATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "PYRANTEL". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "paroxetine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Pyrantin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Pyrantin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported useful
Was the Pyrantin drug useful in terms of decreasing the symptom or the disease?According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
| Users | % | ||
|---|---|---|---|
| Useful | 1 | 100.0% | |
3 consumers reported price estimates
Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Pyrantin drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
| Users | % | ||
|---|---|---|---|
| Not expensive | 2 | 66.7% | |
| Expensive | 1 | 33.3% | |
15 consumers reported time for results
To what extent do I have to use Pyrantin before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Pyrantin. To get the time effectiveness of using Pyrantin drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| 1 day | 6 | 40.0% | |
| > 3 month | 3 | 20.0% | |
| 1 week | 2 | 13.3% | |
| 3 days | 1 | 6.7% | |
| 5 days | 1 | 6.7% | |
| 1 month | 1 | 6.7% | |
| 2 days | 1 | 6.7% | |
51 consumers reported age
| Users | % | ||
|---|---|---|---|
| 1-5 | 32 | 62.7% | |
| 6-15 | 5 | 9.8% | |
| < 1 | 5 | 9.8% | |
| 46-60 | 4 | 7.8% | |
| 16-29 | 4 | 7.8% | |
| 30-45 | 1 | 2.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
