Rejunex indications
Pernicious anemia, both uncomplicated and accompanied by nervous system involvement.
Dietary deficiency of Vitamin B12, occurring in strict vegetarians and in their breast-fed infants. (Isolated vitamin B12 deficiency is very rare).
Malabsorption of vitamin B12, resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates vitamin B12 absorption. These conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). Folate deficiency in these patients is usually more severe than vitamin B12 deficiency.
Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). Total gastrectomy always produces vitamin B12 deficiency.
Structural lesions leading to vitamin B12 deficiency include regional ileitis, ileal resections, malignancies, etc.
Competition for Vitamin B12 by intestinal parasites or bacteria.
The fish tapeworm (Diphyilobothrium latum) absorbs huge quantities of vitamin B12 and infested patients often have associated gastric atrophy. The blind-loop syndrome may produce deficiency of Vitamin B12 or folate.
Inadequate utilization of vitamin B12. This may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia.
For the Schilling Test.
Rejunex description
Rejunex/Rejunex-1500 also contains the following inactive ingredients: Lactose, maize starch, microcrystalline cellulose, povidone (K-30), purified talc, anhydrous colloidal silica, hypromellose, macrogol, titanium dioxide, isopropyl alcohol, dicholoromethane, red iron oxide and yellow iron oxide.
Rejunex dosage
Rejunex: The daily dose is 1 tab 3 times daily.
Rejunex-1500: The daily dose is 1 tab once daily. The dosage should be adjusted according to age of patient and severity of symptoms.
Rejunex interactions
Antibiotics: The use of antibiotics may alter the intestinal microflora and may decrease the possible contribution of Rejunex by certain inhabitants of the microflora (eg, Lactobacillus spp) to the body's requirement for the vitamin. This may particularly be a problem for vegetarians. Garlic, onions, leeks, bananas, asparagus and artichokes, among other vegetables and fruits, contain inulins which promote the growth of certain colonic bacteria including Lactobacillus spp. Cholestyramine:
Colchicine: Colchicine may cause decreased absorption of Rejunex. Colestipol:
H2-Blockers (Cimetidine, Famotidine, Nizatidine, Ranitidine): Chronic use of H2-blockers may result to decreased absorption of Rejunex. They are unlikely to affect the absorption of supplemental B12.
Metformin: Metformin may decrease the absorption of Rejunex. This possible effect may be reversed with oral calcium supplementation.
Nitrous Oxide: Inhalation of the anesthetic agent nitrous oxide (not to be confused with nitric oxide) can produce a functional deficiency. Nitrous oxide forms a complex with cobalt in Rejunex, the cofactor for methionine synthase, resulting in inactivation of the enzyme.
Para-Amino Salicylic Acid: Chronic use of the anti-tuberculosis drug may decrease the absorption of Rejunex.
Potassium Chloride: It has been reported that potassium chloride may decrease the absorption of Rejunex.
Proton Pump Inhibitors (Lansoprazole, Omeprazole, Pantoprazole, Rabeprazole): Chronic use of proton pump inhibitors may result in decreased absorption, naturally found in food sources.
Rejunex side effects
water weight gain, edema, increase in BUN, and dilutional hyponatremia. Asterixis was reported to have worsened in one patient during infusion of this medicine.
Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.
Symptoms may result from an excess or deficit of one or more of the ions present in the solution; therefore, frequent monitoring of electrolyte levels is essential.
Phosphorus deficiency may lead to impaired tissue oxygenation and acute hemolytic anemia. Relative to calcium, excessive phosphorus intake can precipitate hypocalcemia with cramps, tetany and muscular hyperexcitability.
If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.
Rejunex contraindications
Hypersensitivity to Rejunex or other vit B12-containing, cobalamin products or cobalt.
Active ingredient matches for Rejunex:
Mecobalamin in India.
Methylcobalamin in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| Rejunex 500 mcg INJ / 1ml | $ 0.37 |
| REJUNEX 50 MCG INJECTION 1 vial / 1 ML injection each (Intas Pharmaceuticals Ltd) | $ 0.44 |
| REJUNEX inj 500 mcg x 1ml (Intas) | $ 0.37 |
| Rejunex 50mcg Injection (Intas Pharmaceuticals Ltd) | $ 0.48 |
List of Rejunex substitutes (brand and generic names): | |
| Rejumin-DHA (India) | |
| REJUMIN-DHA tab 10's (Jainik) | |
| Rejunex Plus (India) | |
| Rejunex Plus Gamma-linolenic acid 100 mg, Alpha lipoic acid 100 mg, Benfotiamine 100 mg, Elementalzinc 15 mg, methylcobalamin1500 mg. CAP / 7 (Intas) | $ 1.30 |
| REJUNEX PLUS cap 7's (Intas) | $ 1.30 |
| Rejunuron (India) | |
| Rejunuron 500 mcg x 1mL AMP / 1 (Fourrts) | $ 0.71 |
| REJUNURON 500 MCG INJECTION 1 vial / 1 ML injection each (Fourrts) | $ 0.84 |
| REJUNURON inj 500 mcg x 1 mL x 1ml (Fourrts) | $ 0.71 |
| REJUNURON cap 500 mg x 30's (Fourrts) | $ 2.58 |
| Rejunuron 500mcg Injection (Fourrts) | $ 0.90 |
| REJUNURON FORTE | |
| REJUNURON FORTE 1500 MCG/2 ML INJECTION 1 vial / 2 ML injection each (Fourrts India Laboratories Pvt Ltd) | $ 1.18 |
| Rejunuron Forte 1500mcg/ml Injection (Fourrts India Laboratories Pvt Ltd) | $ 1.27 |
| Rejunuron Plus INJ (India) | |
| Rejunuron Plus INJ Thiamine hydrochloride 100 mg, Pyridoxine hydrochloride 100mg, Methylcobalamin 1000 mcg, Nicotinamide 100 mg, D-panthenol 50 mg, Benzylalcohol 2 % v/v/2 mL. INJ / 2ml (Fourrts (Premiere)) | $ 0.90 |
| REJUNURON PLUS INJ inj 2ml (Fourrts (Premiere)) | $ 0.90 |
| Rejunuron-DL (India) | |
| Rejunuron-DL Duloxetine hydrochloride 30mg, Methylcobalamin 750 mg. CAP / 10 (Fourrts) | |
| REJUNURON-DL cap 10's (Fourrts) | $ 0.96 |
| Rejunuron-OD (India) | |
| Rejunuron-OD Methylcobalamin 750 mg, Adenosylcobalamin 750 mg, Vitamin B1 10 mg, Vitamin B2 5mg, Vitamin B6 3 mg, Folicacid 1.5 mg. SG-CAP / 10 (Fourrts (Premiere)) | $ 0.90 |
| REJUNURON-OD soft-gelatin cap 10's (Fourrts (Premiere)) | $ 0.90 |
| Remin-H (India) | |
| Remin-H Methylcobalamin 750 mcg, pregabalin 75 mg. CAP / 10x5 (Spinogen) | $ 6.02 |
| REMIN-H cap 10's (Spinogen) | $ 1.20 |
| Remin-PG (India) | |
| Remin-PG Methylcobalamin 750 mcg, pregabalin 150 mg. CAP / 10x5 (Spinogen) | $ 9.64 |
| REMIN-PG cap 10's (Spinogen) | $ 1.93 |
| Remylin (Bangladesh) | |
| Remylin Methylcobalamin 1500 mcg, Alpha lipoic acid 100 mg, Pyridoxine hydrochloride 3 mg, folic acid 1.5 mg. FC-TAB / 10 (Eris) | $ 1.29 |
| 10's (Eris) | $ 1.29 |
| REMYLIN film-coated tab 10's (Eris) | $ 1.29 |
| Remylin-D (India) | |
| Remylin-D Alpha lipoic acid 100 mg, pyridoxine hydrochloride 3 mg, methylcobalamin 1500 mcg, folic acid 1.5 mg, vitamin D31000 IU. FC-TAB / 10 (Eris) | $ 1.33 |
| REMYLIN-D film-coated tab 10's (Eris) | $ 1.33 |
| Renerve (India) | |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, ChromiumPolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| 10's (Strides) | $ 0.83 |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, Chromiumpolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, Chromiumpolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, Chromiumpolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, ChromiumPolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, Chromiumpolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, ChromiumPolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, ChromiumPolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, Chromiumpolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, ChromiumPolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| RENERVE 1 MG INJECTION 1 vial / 1 ML injection each (Strides) | $ 1.10 |
| RENERVE soft-gelatin cap 15's (Strides) | $ 1.57 |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, ChromiumPolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| Renerve Mecobalamin 500 mcg, Alphalipoic acid 100 mg, Betacarotene 2500 IU, Seleniumdioxide 163.6 mcg, Folic acid5 mg, Calcium pantothenate 10mg, Vitamin B6 1.5 mg, VitaminE 25 mg, Vitamin B1 10 mg, Inositol 100 mg, Chromiumpolynicotinate 200 mcg. SG-CAP / (Strides) | $ 0.83 |
| Renerve 1mg Injection (Strides) | $ 1.10 |
| RENERVE (SWI) | |
| RENERVE 1 MG INJECTION 1 vial / 1 ML injection each (Swiss Pharma Pvt Ltd) | $ 0.92 |
See 3033 substitutes for Rejunex | |
References
- PubChem. "methylcobalamin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "methylcobalamin". http://www.drugbank.ca/drugs/DB03614 (accessed September 17, 2018).
- MeSH. "MeSH Tree: MeSH (Medical Subject Headings) is the NLM controlled vocabulary thesaurus used for indexing articles for PubMed.". http://www.nlm.nih.gov/mesh/meshhome... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Rejunex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Rejunex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported useful
Was the Rejunex drug useful in terms of decreasing the symptom or the disease?According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
| Users | % | ||
|---|---|---|---|
| Useful | 1 | 100.0% | |
Consumer reported price estimates
No survey data has been collected yet2 consumers reported time for results
To what extent do I have to use Rejunex before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes 1 week and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Rejunex. To get the time effectiveness of using Rejunex drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| 1 week | 1 | 50.0% | |
| 1 day | 1 | 50.0% | |
19 consumers reported age
| Users | % | ||
|---|---|---|---|
| > 60 | 9 | 47.4% | |
| 46-60 | 6 | 31.6% | |
| 16-29 | 2 | 10.5% | |
| 6-15 | 1 | 5.3% | |
| 30-45 | 1 | 5.3% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
