Renerve Plus Uses

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Renerve Plus indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Pernicious anemia, both uncomplicated and accompanied by nervous system involvement.

Dietary deficiency of Vitamin B12, occurring in strict vegetarians and in their breast-fed infants. (Isolated vitamin B12 deficiency is very rare).

Malabsorption of vitamin B12, resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates vitamin B12 absorption. These conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). Folate deficiency in these patients is usually more severe than vitamin B12 deficiency.

Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). Total gastrectomy always produces vitamin B12 deficiency.

Structural lesions leading to vitamin B12 deficiency include regional ileitis, ileal resections, malignancies, etc.

Competition for Vitamin B12 by intestinal parasites or bacteria.

The fish tapeworm (Diphyilobothrium latum) absorbs huge quantities of vitamin B12 and infested patients often have associated gastric atrophy. The blind-loop syndrome may produce deficiency of Vitamin B12 or folate.

Inadequate utilization of vitamin B12. This may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia.

For the Schilling Test.

Renerve Plus description

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Renerve Plus/Renerve Plus-1500 also contains the following inactive ingredients: Lactose, maize starch, microcrystalline cellulose, povidone (K-30), purified talc, anhydrous colloidal silica, hypromellose, macrogol, titanium dioxide, isopropyl alcohol, dicholoromethane, red iron oxide and yellow iron oxide.

Renerve Plus dosage

Renerve Plus: The daily dose is 1 tab 3 times daily.

Renerve Plus-1500: The daily dose is 1 tab once daily. The dosage should be adjusted according to age of patient and severity of symptoms.

Renerve Plus interactions

Antibiotics: The use of antibiotics may alter the intestinal microflora and may decrease the possible contribution of Renerve Plus by certain inhabitants of the microflora (eg, Lactobacillus spp) to the body's requirement for the vitamin. This may particularly be a problem for vegetarians. Garlic, onions, leeks, bananas, asparagus and artichokes, among other vegetables and fruits, contain inulins which promote the growth of certain colonic bacteria including Lactobacillus spp.

Cholestyramine: Cholestyramine may decrease the enterohepatic reabsorption of Renerve Plus.

Colchicine: Colchicine may cause decreased absorption of Renerve Plus.

Colestipol: Colestipol may decrease the enterohepatic reabsorption of Renerve Plus.

H2-Blockers (Cimetidine, Famotidine, Nizatidine, Ranitidine): Chronic use of H2-blockers may result to decreased absorption of Renerve Plus. They are unlikely to affect the absorption of supplemental B12.

Metformin: Metformin may decrease the absorption of Renerve Plus. This possible effect may be reversed with oral calcium supplementation.

Nitrous Oxide: Inhalation of the anesthetic agent nitrous oxide (not to be confused with nitric oxide) can produce a functional deficiency. Nitrous oxide forms a complex with cobalt in Renerve Plus, the cofactor for methionine synthase, resulting in inactivation of the enzyme.

Para-Amino Salicylic Acid: Chronic use of the anti-tuberculosis drug may decrease the absorption of Renerve Plus.

Potassium Chloride: It has been reported that potassium chloride may decrease the absorption of Renerve Plus.

Proton Pump Inhibitors (Lansoprazole, Omeprazole, Pantoprazole, Rabeprazole): Chronic use of proton pump inhibitors may result in decreased absorption, naturally found in food sources.

Renerve Plus side effects

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water weight gain, edema, increase in BUN, and dilutional hyponatremia. Asterixis was reported to have worsened in one patient during infusion of this medicine.

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.

Symptoms may result from an excess or deficit of one or more of the ions present in the solution; therefore, frequent monitoring of electrolyte levels is essential.

Phosphorus deficiency may lead to impaired tissue oxygenation and acute hemolytic anemia. Relative to calcium, excessive phosphorus intake can precipitate hypocalcemia with cramps, tetany and muscular hyperexcitability.

If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.

Renerve Plus contraindications

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Hypersensitivity to Renerve Plus or other vit B12-containing, cobalamin products or cobalt.

Active ingredient matches for Renerve Plus:

Mecobalamin in India.

Nicotinamide/pyridoxine hydrochloride in India.


Unit description / dosage (Manufacturer)Price, USD
Renerve Plus Mecobalamin 1000 mcg/2 mL, Pyridoxine hydrochloride 100mg/2 mL, Thiaminehydrochloride 100 mg/2 mL, Niacinamide 100 mg/2 mL, D-panthenol 50 mg/2 mL. INJ / 2ml$ 0.90
2ml$ 0.90
RENERVE PLUS inj 2ml (Strides)$ 0.99

List of Renerve Plus substitutes (brand and generic names):

Renerve Plus Cap Mecobalamin 1500 mcg, Alphalipoic acid 100 mg, Folic acid5 mg, Inositol 100 mg, Chromium polynicotinate 200mcg, Selenium dioxide 163.6mcg, Vitamin E acetate 25 mg, Thiamine hydrochloride 10 mg, Calcium pantothenate 10 mg, Pyridoxine 1.5 mg, v (Strides)$ 1.55
10's$ 0.96
Rouvit 1500 mcg INJ / 2ml (Rouzel)
1500 mcg x 2ml (Rouzel)
ROUVIT inj 1500 mcg x 2ml (Rouzel)
Rouvit Plus Mecobalamin 1000 mcg, Pyridoxine hydrochloride 100mg, niacinamide 100 mg. INJ / 2ml (Rouzel)
2ml (Rouzel)
ROUVIT PLUS inj 2ml (Rouzel)
Rudimin-Alpha Alpha lipoic acid 200 mg, mecobalamin 750 mcg, folicacid 1.5 mg, pyridoxinehydrochloride 3 mg. CAP / 10 (Shield)$ 1.11
RUDIMIN-ALPHA cap 10's (Shield)$ 1.11
Safyvit Mecobalamin 1000 mcg, VitaminB1 100 mg, Vitamin B6 100 mg, D-panthenol 50 mg, nicotinamide. VIAL / 1 (Sanify)$ 0.60
1's (Sanify)$ 0.60
SAFYVIT inj 2ml (Sanify)$ 0.60
Safyvit M 1500 mcg Tablet (Syntonic (Sanify Healthcare Pvt Ltd))$ 0.08
Safyvit Syr Mecobalamin 500 mcg, Folicacid 1500 mcg. SYR / 100ml (Sanify)$ 0.47
100ml (Sanify)$ 0.47
SAFYVIT SYR syr 100ml (Sanify)$ 0.47
Safyvit-M 1500 mcg TAB / 10 (Sanify (Syntonic))$ 0.84
1500 mcg x 10's (Sanify (Syntonic))$ 0.84
SAFYVIT-M tab 1500 mcg x 10's (Sanify (Syntonic))$ 0.84
Salcob 1500 mcg AMP / 1 (Salvus)
1500 mcg x 1's (Salvus)
SALCOB inj 1500 mcg x 2ml (Salvus)
Salcob Plus Mecobalamin 1000 mcg, Pyridoxine 100 mg, Niacinamide100 mg. VIAL / 1 (Salvus)
1's (Salvus)
SALCOB PLUS inj 1's (Salvus)
Salcob-G Gabapentin 300 mg, Mecobalamin500 mcg. CAP / 10 (Salvus)
10's (Salvus)
SALCOB-G cap 10's (Salvus)
Salcob-OD Mecobalamin 1500 mcg, Alphalipoic acid 100 mg, Pyridoxinehydrochloride 3 mg. S-GEL / 10 (Salvus)
10's (Salvus)
SALCOB-OD softgel 10's (Salvus)
Salute INJ 500 mcg AMP / 1ml (Vensat)$ 0.22
500 mcg x 1ml (Vensat)$ 0.22
SALUTE INJ inj 500 mcg x 1ml (Vensat)$ 0.22
Salute MD 1000 mcg Injection (Vensat Bio)$ 0.30
Salute-MD INJ Mecobalamin 1 mg, Vitamins. AMP / 2ml (Vensat)$ 0.59
2ml (Vensat)$ 0.59
SALUTE-MD INJ inj 2ml (Vensat)$ 0.59

References

  1. DailyMed. "ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PHYTONADIONE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN 5'-PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN; THIAMINE; TOCOPHEROL ACETATE; VITAMIN A; VITAMIN K: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. PubChem. "nicotinamide". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Renerve Plus are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Renerve Plus. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

2 consumers reported useful

Was the Renerve Plus drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Useful2
100.0%


3 consumers reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Renerve Plus drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Expensive2
66.7%
Not expensive1
33.3%


5 consumers reported time for results

To what extent do I have to use Renerve Plus before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 5 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Renerve Plus. To get the time effectiveness of using Renerve Plus drug by other patients, please click here.
Users%
5 days1
20.0%
1 day1
20.0%
1 week1
20.0%
3 month1
20.0%
2 days1
20.0%


25 consumers reported age

Users%
> 609
36.0%
46-607
28.0%
30-457
28.0%
6-151
4.0%
1-51
4.0%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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