Tidilor Uses

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What is Tidilor?

Tidilor is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Tidilor is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.

Tidilor is also used to treat skin hives and itching in people with chronic skin reactions.

Tidilor may also be used for purposes not listed in this medication guide.

Tidilor indications

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Treatment of seasonal allergic rhinitis, perennial rhinitis, urticaria, allergic dermatologic disorders, angioedema and conjunctivitis. Tidilor is generally considered to be ineffective in asthma.

Acute anaphylaxis should be treated with adrenaline; Tidilor and corticosteroids are given to prevent relapse.

Tidilor is also used to control the pruritus associated with skin disorders eg, atopic eczema.

How should I use Tidilor?

Use Tidilor orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Tidilor orally disintegrating tablets.

Uses of Tidilor in details

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This medication is an antihistamine that treats symptoms such as itching, runny nose, watery eyes, and sneezing from "hay fever" and other allergies. It is also used to relieve itching from hives.

Tidilor does not prevent hives or prevent/treat a serious allergic reaction (e.g., anaphylaxis). Therefore, if your doctor has prescribed epinephrine to treat allergic reactions, always carry your epinephrine injector with you. Do not use Tidilor in place of your epinephrine.

If you are self-treating with this medication, it is important to read the manufacturer's package instructions carefully so you know when to consult your doctor or pharmacist.

Do not use this medication in children younger than 6 years unless directed by the doctor. If you are using the chewable tablets, do not use in children younger than 2 years unless directed by your doctor.

How to use Tidilor

If you are using the over-the-counter product to self-treat, read all the directions on the product package before taking this medication. If your doctor has prescribed this medication, follow your doctor's directions and the instructions on your prescription label. If you have any questions, consult your doctor or pharmacist.

Take this medication by mouth with or without food, usually once a day or as directed by your doctor or the product package. If you are using the chewable tablets, chew each tablet well and swallow. Dosage is based on your age, condition, and response to treatment. Do not increase your dose or take this drug more often than directed. Do not take more of this medication than recommended for your age.

Tell your doctor if your allergy symptoms do not improve after 3 days of treatment or if your hives last more than 6 weeks. Seek immediate medical attention if your condition worsens or you think you have a serious medical problem (e.g., very serious allergic reaction/anaphylaxis).

Tidilor description

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Tidilor competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. Tidilor's anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease.

Tidilor dosage

Tidilor Dosage

Applies to the following strength(s): 10 mg; 5 mg/5 mL; 5 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Allergic Rhinitis

10 mg orally once a day

Usual Adult Dose for Urticaria

10 mg orally once a day

Usual Pediatric Dose for Allergic Rhinitis

2 to 5 years: 5 mg orally once a day (syrup)

6 years or older: 10 mg orally once a day (tablets, capsule, and disintegrating tablets)

Usual Pediatric Dose for Urticaria

2 to 5 years: 5 mg orally once a day (syrup)

6 years or older: 10 mg orally once a day (tablets, capsule, and disintegrating tablets)

Renal Dose Adjustments

CrCl less than 30 mL/min: administer dosage every other day initially

Liver Dose Adjustments

Liver failure: administer dosage every other day initially

Dialysis

Tidilor is not significantly removed by hemodialysis, thus supplementary dosing is not required following hemodialysis.

More about Tidilor

Consumer resources

Professional resources

Related treatment guides

Tidilor interactions

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What other drugs will affect Tidilor?

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Tidilor (10 mg once daily) has been coadministered with therapeutic doses of erythromycin, cimetidine, and ketoconazole in controlled clinical pharmacology studies in adult volunteers. Although increased plasma concentrations (AUC 0-24 hrs) of Tidilor and/or descarboethoxyloratadine were observed following coadministration of Tidilor with each of these drugs in normal volunteers (n = 24 in each study), there were no clinically relevant changes in the safety profile of Tidilor, as assessed by electrocardiographic parameters, clinical laboratory tests, vital signs, and adverse events. There were no significant effects on QTc intervals, and no reports of sedation or syncope. No effects on plasma concentrations of cimetidine or ketoconazole were observed. Plasma concentrations (AUC 0-24 hrs) of erythromycin decreased 15% with coadministration of Tidilor relative to that observed with erythromycin alone. The clinical relevance of this difference is unknown. These above findings are summarized in TABLE 1.

TABLE 1 Effects on Plasma Concentrations (AUC 0-24 hrs) of Tidilor and Descarboethoxyloratadine After 10 Days of Coadministration (Tidilor 10 mg) in Normal Volunteers
Tidilor Descarboethoxyloratadine
Erythromycin (500 mg q8h) + 40% +46%
Cimetidine (300 mg qid) +103% + 6%
Ketoconazole (200 mg q12h) +307% +73%

Tidilor side effects

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What are the possible side effects of Tidilor?

Applies to Tidilor: oral fixed-combination tablets, oral orally disintegrating tablets, oral solution, oral tablets

Side effects include:

Children 2–5 years of age receiving oral solution: Diarrhea, epistaxis, pharyngitis, flu-like symptoms, fatigue, stomatitis, tooth disorder, earache, viral infection, rash.

Children 6–12 years of age receiving oral solution: Nervousness, wheezing, fatigue, hyperkinesia, abdominal pain, conjunctivitis, dysphonia, upper respiratory tract infection.

Adults and children ≥12 years of age receiving conventional or orally disintegrating tablets: Headache, somnolence, fatigue, dry mouth.

Fixed combination Tidilor (the active ingredient contained in Tidilor Reditab) pseudoephedrine sulfate preparations: Insomnia, dry mouth, headache, somnolence, nervousness, dizziness, fatigue.

Tidilor contraindications

See also:
What is the most important information I should know about Tidilor?

Do NOT use Tidilor if:

you are allergic to any ingredient in Tidilor

Contact your doctor or health care provider right away if any of these apply to you.



Active ingredient matches for Tidilor:

Loratadine in Oman.


List of Tidilor substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Ticevis 10 mg x 10 Blister x 10 Tablet
Tidor 10mg TAB / 100 (Biochemie (Novartis India Limited))$ 2.35
10 mg x 100's (Biochemie (Novartis India Limited))$ 2.35
Tidor 10 mg Tablet (Biochemie (Novartis India Limited))$ 0.02
TIDOR tab 10 mg x 10's (Biochemie (Novartis India Limited))$ 0.23
Tinnic 10 mg x 5 x 10's (Nicholas)$ 15.50
Tiradine 10 mg x 10 x 10's (British dispensary)
Tablet; Oral; Loratadine 10 mg (Sandoz (Novartis India Ltd))
Tirlor 10mg TAB / 100 (Sandoz (Novartis India Ltd))$ 2.35
10 mg x 100's (Sandoz (Novartis India Ltd))$ 2.35
Tirlor 10 mg x 100's (Sandoz (Novartis India Ltd))
Tirlor 10 mg Tablet (Sandoz (Novartis India Ltd))$ 0.02
TIRLOR 10 MG TABLET 1 strip / 10 tablets each (Sandoz (Novartis India Ltd))$ 0.23
TIRLOR tab 10 mg x 10's (Sandoz (Novartis India Ltd))$ 0.23
Tirlor 10mg Tablet (Sandoz (Novartis India Ltd))$ 0.02
Topcare Allergy Relief tablet, film coated 180 mg/1 (Topco Associates LLC (US))
Topcare Allergy Relief tablet, orally disintegrating 10 mg/1 (Topco Associates LLC (US))
Topcare Allergy Relief 24 Hour tablet 10 mg/1 (Topco Associates LLC (US))
Injectable; Injection; Ketorolac Tromethamine 30 mg / ml (Ivax)
Tablet; Oral; Ketorolac Tromethamine 10 mg (Ivax)
Toral 10 mg x 100's (Ivax)
Toral 5 mg/5 mL x 60 mL (Ivax)
Tablet; Oral; Loratadine 10 mg
U Chu Loratadine 10 mg x 20 Tablet
Ubitlor 10 mg Tablet (Ubit Pharmaceuticals Pvt Ltd)$ 0.03
Uradine 10 mg x 3 Blister x 10 Tablet
Urtilar 10 mg x 50's$ 21.08
Vaco Loratadine 10 mg x 10 Blister x 10 Tablet
Vaco Loratadine 10 mg x 1 Bottle 100 Tablet

References

  1. DailyMed. "LORATADINE; PSEUDOEPHEDRINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "loratadine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "loratadine". http://www.drugbank.ca/drugs/DB00455 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Tidilor are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Tidilor. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

1 consumer reported useful

Was the Tidilor drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Useful1
100.0%


Consumer reported price estimates

No survey data has been collected yet


5 consumers reported time for results

To what extent do I have to use Tidilor before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Tidilor. To get the time effectiveness of using Tidilor drug by other patients, please click here.
Users%
1 day2
40.0%
1 month1
20.0%
3 month1
20.0%
5 days1
20.0%


19 consumers reported age

Users%
16-298
42.1%
30-454
21.1%
1-53
15.8%
< 12
10.5%
> 601
5.3%
6-151
5.3%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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