Zenflox-Oz Uses

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Zenflox-Oz indications

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To reduce the development of drug-resistant bacteria and maintain the effectiveness of (Zenflox-Oz tablets) Tablets and other antibacterial drugs, (Zenflox-Oz tablets) Tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

(Zenflox-Oz tablets) Tablets are indicated for the treatment of adults with mild to moderate infections (unless otherwise indicated) caused by susceptible strains of the designated microorganisms in the infections listed below.

Acute bacterial exacerbations of chronic bronchitis due to Haemophilus influenzae or Streptococcus pneumoniae.

Community-acquired Pneumonia due to Haemophilus influenzae or Streptococcus pneumoniae.

Uncomplicated skin and skin structure infections due to methicillin-susceptible Staphylococcus aureus, Streptococcus pyogenes, or Proteus mirabilis.

Acute, uncomplicated urethral and cervical gonorrhea due to Neisseria gonorrhoeae.

Nongonococcal urethritis and cervicitis due to Chlamydia trachomatis.

Mixed Infections of the urethra and cervix due to Chlamydia trachomatis and Neisseria gonorrhoeae.

Acute pelvic inflammatory disease (including severe infection) due to Chlamydia trachomatis and/or Neisseria gonorrhoeae.

NOTE: If anaerobic microorganisms are suspected of contributing to the infection, appropriate therapy for anaerobic pathogens should be administered.

Uncomplicated cystitis due to Citrobacter diversus, Enterobacter aerogenes, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, or Pseudomonas aeruginosa.

Complicated urinary tract infections due to Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Citrobacter diversus*, or Pseudomonas aeruginosa*.

Prostatitis due to Escherichia coli.

Zenflox-Oz dosage

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Dosing regimen of Zenflox-Oz is individual. Daily dose of 200-800 mg, the multiplicity of application 2 times / day. For patients with impaired renal function (creatinine clearance 20-50 ml / min), the first dose is 200 mg, then 100 mg every 24 hours. When CC is less than 20 ml / min, the first dose is 200 mg, then 100 mg every 48 hours.

Zenflox-Oz interactions

Simultaneous administration of Zenflox-Oz with:

  • antacids containing calcium, magnesium or aluminum, with sucralfate, with preparations containing two-and trivalent cations, such as iron, or multivitamins containing zinc it may be in breach absorption of quinolones, resulting in a decrease in their concentration in the body. These medications should not be used for 2 hours before or within 2 hours after taking Zenflox-Oz.
  • NSAIDs increases the risk of stimulating effect on the central nervous system and seizures.
  • theophylline may increase its concentration in blood plasma (including the equilibrium state), increasing half-life. This increases the risk of adverse reactions associated with the action of theophylline.
  • beta-lactam antibiotics, aminoglycosides and metronidazole there were observed additive interaction.

    Zenflox-Oz side effects

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    Digestive system: nausea, vomiting, diarrhea, abdominal pain and cramps, appetite loss, dry mouth, flatulence, gastrointestinal dysfunction, constipation; rarely - liver damage, liver necrosis, jaundice, hepatitis, intestinal perforation, pseudomembranous colitis, bleeding from the gastrointestinal tract, disorders of the oral mucosa, heartburn, elevated liver enzymes, including GGT and LDH, increased serum bilirubin.

    CNS and peripheral nervous system: insomnia, dizziness, fatigue, drowsiness, nervousness; rarely - convulsions, anxiety, cognitive changes, depression, abnormal dreams, euphoria, hallucinations, paresthesia, syncope, tremor, confusion, nystagmus, suicidal thoughts or attempts, disorientation, psychotic reactions, paranoia, phobia, agitation, aggressiveness, emotional instability, peripheral neuropathy, ataxia, incoordination, exacerbation of extrapyramidal disorders, speech disorder.

    Allergic reactions: skin rash, itching, rarely - angioedema, urticaria, vasculitis, allergic pneumonitis, anaphylactic shock, erythema multiforme, Stevens-Johnson syndrome, erythema nodosum, exfoliative dermatitis, toxic epidermal necrolysis, conjunctivitis.

    Sexual system: an itch on the external genitalia in women, vaginitis, vaginal discharge; rare - burning, irritation, pain and rash in the genital area of women, dysmenorrhea, menorrhagia, metrorrhagia, vaginal candidiasis.

    Cardiovascular system: rarely - heart failure, edema, hypertension, hypotension, palpitation, vasodilatation, cerebral thrombosis, pulmonary edema, and tachycardia.

    Urinary system: rarely - dysuria, urinary frequency, urinary retention, anuria, polyuria formation of kidney stones, kidney failure, nephritis, hematuria, albuminuria, candiduria.

    Musculoskeletal system: rarely - arthralgia, myalgia, tendonitis, muscle weakness, exacerbation of myasthenia gravis.

    Metabolism: rarely - thirst, weight loss, hyper- or hypoglycemia (especially in patients with diabetes mellitus receiving insulin or oral hypoglycemic agents), acidosis, increase in serum triglycerides, cholesterol, potassium.

    Respiratory system: rarely - cough, runny nose, respiratory failure, dyspnea, bronchospasm, stridor.

    Sensory organs: rarely - hearing loss, tinnit, diplopia, nystagmus, impaired clarity of vision, disturbances of taste, smell, photophobia.

    Dermatological reactions: rarely - photosensitivity, hyperpigmentation, vesicle-bullous eruption.

    Hematopoietic system: rarely - anemia, hemorrhage, pancytopenia, agranulocytosis, leukopenia, reversible suppression of bone marrow hematopoiesis, thrombocytopenia, thrombocytopenic purpura, petechiae, ecchymosis, increased prothrombin time.

    Other: chest pain, sore throat, fever, body aches, rarely - fatigue, chills, malaise, epistaxis, increased sweating.

    Zenflox-Oz contraindications

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    Pregnancy, lactation, childhood and adolescence to 18 years, increased sensitivity to Zenflox-Oz or other quinolone derivatives.

    Active ingredient matches for Zenflox-Oz:

    Ofloxacin/Ornidazole in India.

    Ofloxacin

    Ornidazole


    Unit description / dosage (Manufacturer)Price, USD
    Zenflox-Oz Capsule/ Tablet / 200mg-600mg / 6 units (Mankind Pharma)$ 0.47
    6's$ 0.33
    30ml$ 0.24
    Zenflox-OZ Ofloxacin 200 mg, Ornidazole500 mg. FC-TAB / 6$ 0.33
    Zenflox-OZ Ofloxacin 50 mg, Ornidazole125 mg/5 mL. SUSP / 30ml$ 0.24
    ZENFLOX-OZ film-coated tab 6's (Mankind)$ 0.38
    ZENFLOX-OZ oral susp 30ml (Mankind)$ 0.30
    ZENFLOX-OZ infusion 100ml (Mankind)$ 0.91
    Zenflox-OZ Ofloxacin 200 mg, Ornidazole500 mg. FC-TAB / 6$ 0.33
    Zenflox-OZ Ofloxacin 50 mg, Ornidazole125 mg/5 mL. SUSP / 30ml$ 0.24
    Zenflox-OZ 50mg/125mg Suspension (Mankind Pharma Ltd)$ 0.48
    Zenflox-OZ Tablet (Mankind Pharma Ltd)$ 0.10

    List of Zenflox-Oz substitutes (brand and generic names):

    ZENFLOX UTI 200 MG/200 MG TABLET 1 strip / 10 tablets each (Discovery (Mankind Pharmaceuticals Pvt. Ltd.))$ 1.69
    ZENOCIN OD 800MG TABLET 1 strip / 5 tablets each (Ranbaxy Laboratories Ltd)$ 1.29
    Zenof 100mg TAB / 10 (Zenon Healthcare)$ 0.35
    Zenof 200mg TAB / 10 (Zenon Healthcare)$ 0.63
    Zenof 400mg TAB / 10 (Zenon Healthcare)$ 1.14
    Zenof 50mg/ml SUSP / 60ml (Zenon Healthcare)$ 0.49
    50 mg x 5 mL x 60ml (Zenon Healthcare)$ 0.49
    100 mg x 10's (Zenon Healthcare)$ 0.35
    200 mg x 10's (Zenon Healthcare)$ 0.63
    400 mg x 10's (Zenon Healthcare)$ 1.14
    Zenof 200 mg Tablet (Zenon Healthcare)$ 0.06
    Zenof 400 mg Tablet (Zenon Healthcare)$ 0.11
    Zenof 200+LB Izen Tablet (Zenon Healthcare)$ 0.07
    Zenof 60 ml Suspension (Zenon Healthcare)$ 0.04
    Zenof 100 mg Tablet (Zenon Healthcare)$ 0.03
    ZENOF oral susp 50 mg x 5 mL x 60ml (Zenon Healthcare)$ 0.49
    ZENOF tab 100 mg x 10's (Zenon Healthcare)$ 0.35
    ZENOF tab 200 mg x 10's (Zenon Healthcare)$ 0.63
    ZENOF tab 400 mg x 10's (Zenon Healthcare)$ 1.14
    Zenof M 60 ml Suspension (Zenon Healthcare)$ 0.04
    Zenof OZ 30 ml Suspension (Zenon Healthcare)$ 0.07
    ZENOF-OZ oral susp 30ml (Zenon)
    ZENOF-OZ tab 10's (Zenon)
    Zenoflo OR 200+500 Tablet (Kaizen Drugs (P) Ltd.)$ 0.10
    Zenosam 200 mg Tablet (Samcure Drugs & Pharmaceuticals Pvt Ltd)$ 0.06
    Zenosam-200 200mg TAB / 10$ 0.59
    Zenotas 200 mg Tablet (Intas Laboratories Pvt Ltd)$ 0.11
    Zenotas 30 ml Suspension (Intas Laboratories Pvt Ltd)$ 0.08
    ZENOTAS 200MG TABLET 1 strip / 10 tablets each (Intas Laboratories Pvt Ltd)$ 0.18
    ZENOTAS oral susp 50 mg x 5 mL x 30ml (Intas Laboratories Pvt Ltd)$ 0.25
    ZENOTAS tab 200 mg x 10's (Intas Laboratories Pvt Ltd)$ 0.61
    Zenotas 200mg Tablet (Intas Laboratories Pvt Ltd)$ 0.02
    Zenotas OZ 200+500 Tablet (Intas Laboratories Pvt Ltd)$ 0.13
    Zenotas OZ 30 ml Suspension (Intas Laboratories Pvt Ltd)$ 0.09
    ZENOTAS-OZ film-coated tab 10's (Intas)$ 1.33
    ZENOTAS-OZ oral susp 30ml (Intas)$ 0.55
    Zenotin NF Suspension (Mankind Pharma Ltd)$ 0.39
    Zeo O 200+500 Tablet (Zuvista (Zuventus Health Care Ltd.))$ 0.09
    ZEOF Dispersible Tablet / 100mg / 10 units (Zuventus Health Care Ltd.)$ 0.25
    ZEOF Liquid / 50mg/5ml / 30ml units (Zuventus Health Care Ltd.)$ 0.29

    References

    1. DailyMed. "OFLOXACIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
    2. PubChem. "ofloxacin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
    3. PubChem. "Ornidazole". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

    Reviews

    The results of a survey conducted on ndrugs.com for Zenflox-Oz are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Zenflox-Oz. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

    User reports

    Consumer reported useful

    No survey data has been collected yet


    Consumer reported price estimates

    No survey data has been collected yet


    3 consumers reported time for results

    To what extent do I have to use Zenflox-Oz before I begin to see changes in my health conditions?
    As part of the reports released by ndrugs.com website users, it takes 3 days and a few days before you notice an improvement in your health conditions.
    Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Zenflox-Oz. To get the time effectiveness of using Zenflox-Oz drug by other patients, please click here.
    Users%
    3 days1
    33.3%
    2 weeks1
    33.3%
    5 days1
    33.3%


    2 consumers reported age

    Users%
    16-292
    100.0%


    Consumer reviews


    There are no reviews yet. Be the first to write one!


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    Information checked by Dr. Sachin Kumar, MD Pharmacology

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