Aptol Duriles indications
Oral
Hypertension
Adult: 200 mg/day in divided doses, increased wkly according to patient response.
Oral
Angina pectoris; Cardiac arrhythmias
Adult: 200-400 mg/day in divided doses.
Aptol Duriles description
One of the adrenergic beta-antagonists used as an antihypertensive, anti-anginal, and anti-arrhythmic agent. Aptol Duriles is no longer marketed by AstraZeneca, but may still be available in generic varieties.
Aptol Duriles dosage
Oral
Hypertension
Adult: 200 mg/day in divided doses, increased wkly according to patient response.
Oral
Angina pectoris; Cardiac arrhythmias
Adult: 200-400 mg/day in divided doses.
Aptol Duriles interactions
Concomitant use w/ other drugs that cause hypotension; NSAIDs; other cardiac depressants; sotalol; digoxin; insulin and oral hypoglycaemics; sympathomimetics; ACE inhibitors; Ca-channel blockers, verapamil. Anaesthetics causing myocardial depression (e.g. ether, cyclopropane, trichloroethylene).
Potentially Fatal: Increased risk of withdrawal HTN w/ clonidine. Withdraw several days before slowly discontinuing clonidine.
Aptol Duriles side effects
Bradycardia; heart failure, heart block; hypotension; bronchospasm; fatigue; coldness of extremities; pneumonitis; pulmonary and retroperitoneal fibrosis; pleurisy; CNS effects; myopathies; GI disturbances; reversible alopoecia; skin rash; pruritus; lupus-like syndrome; male impotence; sclerosing peritonitis; muscle cramps; paraesthesias; peripheral neuropathy; haematological reactions. Changes in blood concentrations of glucose, triglycerides and cholesterol.
Aptol Duriles contraindications
2nd and 3rd degree AV block; sinus bradycardia; uncontrolled heart failure; asthma or bronchospasm, severe peripheral arterial disease, metabolic acidosis, phaeochromocytoma. Concomitant use w/ clonidine.
Active ingredient matches for Aptol Duriles:
List of Aptol Duriles substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Alfeprol | |
| Alprenolol | |
| Alprénolol | |
| Apllobal | |
| Aptin (Australia, Germany, Norway, Denmark) | |
| Aptin N (Sweden) | |
| Aptine (France, Belgium) | |
| Atenenol (Japan) | |
| Elp (Taiwan) | |
| Elp 50 mg x 500's (Shyh Dar) | |
| Elp 50 mg x 100 x 10's (Shyh Dar) | |
|
sponsored
| |
| Gubernal | |
| Regletin | |
| Skajilol (Japan) | |
| Yobir | |
References
- PubChem. "alprenolol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "alprenolol". http://www.drugbank.ca/drugs/DB00866 (accessed September 17, 2018).
- MeSH. "Sympatholytics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Aptol Duriles are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Aptol Duriles. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
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Information checked by Dr. Sachin Kumar, MD Pharmacology
