Yobir indications
Oral
Hypertension
Adult: 200 mg/day in divided doses, increased wkly according to patient response.
Oral
Angina pectoris; Cardiac arrhythmias
Adult: 200-400 mg/day in divided doses.
Yobir description
One of the adrenergic beta-antagonists used as an antihypertensive, anti-anginal, and anti-arrhythmic agent. Yobir is no longer marketed by AstraZeneca, but may still be available in generic varieties.
Yobir dosage
Oral
Hypertension
Adult: 200 mg/day in divided doses, increased wkly according to patient response.
Oral
Angina pectoris; Cardiac arrhythmias
Adult: 200-400 mg/day in divided doses.
Yobir interactions
Concomitant use w/ other drugs that cause hypotension; NSAIDs; other cardiac depressants; sotalol; digoxin; insulin and oral hypoglycaemics; sympathomimetics; ACE inhibitors; Ca-channel blockers, verapamil. Anaesthetics causing myocardial depression (e.g. ether, cyclopropane, trichloroethylene).
Potentially Fatal: Increased risk of withdrawal HTN w/ clonidine. Withdraw several days before slowly discontinuing clonidine.
Yobir side effects
Bradycardia; heart failure, heart block; hypotension; bronchospasm; fatigue; coldness of extremities; pneumonitis; pulmonary and retroperitoneal fibrosis; pleurisy; CNS effects; myopathies; GI disturbances; reversible alopoecia; skin rash; pruritus; lupus-like syndrome; male impotence; sclerosing peritonitis; muscle cramps; paraesthesias; peripheral neuropathy; haematological reactions. Changes in blood concentrations of glucose, triglycerides and cholesterol.
Yobir contraindications
2nd and 3rd degree AV block; sinus bradycardia; uncontrolled heart failure; asthma or bronchospasm, severe peripheral arterial disease, metabolic acidosis, phaeochromocytoma. Concomitant use w/ clonidine.
Active ingredient matches for Yobir:
List of Yobir substitutes (brand and generic names) | Sort by popularity |
Unit description / dosage (Manufacturer) | Price, USD |
Alfeprol | |
Alprenolol | |
Alprénolol | |
Apllobal | |
Aptin (Australia, Germany, Norway, Denmark) | |
Aptin N (Sweden) | |
Aptine (France, Belgium) | |
Aptol Duriles | |
Atenenol (Japan) | |
Elp (Taiwan) | |
Elp 50 mg x 500's (Shyh Dar) | |
sponsored
| |
Elp 50 mg x 100 x 10's (Shyh Dar) | |
Gubernal | |
Regletin | |
Skajilol (Japan) |
References
- PubChem. "alprenolol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "alprenolol". http://www.drugbank.ca/drugs/DB00866 (accessed September 17, 2018).
- MeSH. "Sympatholytics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Yobir are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Yobir. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology