Depiwhite Uses

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What is Depiwhite?

Depiwhite decreases the formation of melanin in the skin. Melanin is the pigment in skin that gives it a brown color.

Depiwhite topical (for the skin) is used to lighten areas of darkened skin such as freckles, age spots, melasma (sun damage), or chloasma (darkened skin caused by hormonal changes).

Depiwhite topical may also be used for purposes not listed in this medication guide.

Depiwhite indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Depiwhite 4% CREAMNUQUIN HP 4% CREAM, NUQUIN HP 4% GEL, MELPAQUE HP 4% CREAM, MELQUIN HP 4% CREAM and Depiwhite (Depiwhite 3% topical solution) are indicated for the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other undesired areas of melanin hyperpigmentation.

How should I use Depiwhite?

Use Depiwhite cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Depiwhite cream.

Uses of Depiwhite in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Depiwhite is used to lighten the dark patches of skin (also called hyperpigmentation, melasma, "liver spots," "age spots," freckles) caused by pregnancy, birth control pills, hormone medicine, or injury to the skin.

This medicine works by blocking the process in the skin that leads to discoloration.

How to use Depiwhite topical

Follow all directions on the product package, or use as directed by your doctor. Before using, apply a small amount of this medicine to an area of unbroken skin, and check the area within 24 hours for any serious side effects. If the test area is itching, red, puffy, or blistering, do not use this product and contact your doctor. If there is just mild redness, then treatment with this product may begin.

Apply this medication to the affected areas of skin, usually twice daily or as directed by your doctor. This medication is for use on the skin only. If it is used incorrectly, unwanted skin lightening may occur. Avoid getting this product in your eyes or on the inside of your nose or mouth. If you do get this medication in those areas, flush with plenty of water.

This medication may make the treated areas of skin more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing on the treated areas of skin when outdoors.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.

Inform your doctor if your condition persists or worsens after 2 months.

Depiwhite description


Depiwhite is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen. Depiwhite has come under scrutiny due to several complications associated with its use, including dermal irritation, exogenous onchronosis, and carginogenicity. As a result of these concerns, Depiwhite has been banned in the EU and UK.

Depiwhite dosage

Depiwhite Dosage

Generic name: Depiwhite 40mg in 1g

Dosage form: gel

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The information at is not a substitute for medical advice. Always consult your doctor or pharmacist.

Depiwhite® should be applied to the affected areas twice daily, morning and before bedtime or as directed by a physician.

During and after the use of Depiwhite®, sun exposure should be limited and a sunscreen agent or protective clothing should be used to cover up the treated areas to prevent regimentation. If no lightening effect is noted after two months of treatment, use of Depiwhite® should be discontinued. There is no recommended dosage for children under the age of 12 years of age except under the advice and supervision of a physician.

More about Depiwhite (Depiwhite topical)

Consumer resources

Other brands: Depiwhite and Sunscreen, Depiwhite, Melquin HP, Eldoquin, More... (15)

Professional resources

Related treatment guides

Depiwhite interactions

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What other drugs will affect Depiwhite?


Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.

Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Depiwhite side effects

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What are the possible side effects of Depiwhite?

Mild burning, stinging, redness, and dryness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

If your doctor has prescribed this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Stop using Depiwhite and tell your doctor right away if any of these unlikely but serious side effects occur: blistering, skin cracking, blue-black darkening of the skin.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Depiwhite contraindications

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What is the most important information I should know about Depiwhite?

Before using Depiwhite topical, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.

Do not use Depiwhite topical on skin that is sunburned, windburned, dry, chapped, or irritated, or on an open wound. It could make these conditions worse. Wait until these conditions have healed before applying Depiwhite topical.

Avoid getting this medication in your mouth or eyes. If it does get into any of these areas, rinse with water.

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Do not use other medicated skin products unless your doctor has told you to.

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Depiwhite topical can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

Active ingredient matches for Depiwhite:

Hydroquinone in India.


Kojic acid/Vitamin C

Aluminium silicate/kojic acid/lactic acid/vitamin C in India.

Unit description / dosage (Manufacturer)Price, USD
Depiwhite Hydroquinone 2 %, kojic acid 2%, aluminium silicate 1 %, vitamin C 0.5 %, lactic acid0.2 %. CRM / 15ml$ 3.37
DEPIWHITE cream 15gm (Wockhardt (Derma))$ 8.25

List of Depiwhite substitutes (brand and generic names):

DEPIG-TM cream 15g (Intermed)$ 1.83
Ointment; Topical; Beeswax 0.6%; Comfrey 12%; Olive Oil 1.8%; Peppermint Oil 0.3%; Tallow 85% (Ego)
Liquid; Topical; Hydrocortisone 1%
Spray; Topical; Hydrocortisone 1%
Solution; Topical; Hydrocortisone 1%
Cream; Topical; Hydrocortisone Acetate 1% (Neolab)
Lotion; Topical; Hydrocortisone Acetate 1% (Neolab)
Cream; Topical; Hydrocortisone 1% (Ego)
DermAid 0.5 % x 15 g (Ego)
DermAid 0.5 % x 30 g (Ego)
DermAid 0.5 % x 15 g x 1's (Ego)
Cream; Topical; Hydrocortisone 0.5% (Ego)
DermAid cream 0.5% 15 g x 1's (Ego)
DermAid cream 0.5 % 15 g x 1's (Ego)
Cream; Topical; Hydrocortisone 1%
Cream; Topical; Hydrocortisone 1% (Ratiopharm)
Cream; Topical; Hydrocortisone 0.5% (Del)
Cream; Topical; Hydrocortisone Acetate 0.5%
Dermicort 1 tube 10 g
Ointment; Topical; Hydrocortisone (Kade)
Dermofade Skin 60 ml Lotion (Gary Pharmaceuticals Pvt. Ltd.)$ 1.03
Dermofade Skin 30 gm Cream (Gary Pharmaceuticals Pvt. Ltd.)$ 0.57
DERMOFADE CREAM 1 tube / 30 GM cream each (Gary Pharmaceuticals Pvt. Ltd.)$ 0.60


  1. DailyMed. "FLUOCINOLONE ACETONIDE; HYDROQUINONE; TRETINOIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". (accessed September 17, 2018).
  2. DailyMed. "LACTIC ACID: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". (accessed September 17, 2018).
  3. DailyMed. "CIPROFLOXACIN HYDROCHLORIDE; HYDROCORTISONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". (accessed September 17, 2018).


The results of a survey conducted on for Depiwhite are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Depiwhite. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet

Consumer reported price estimates

No survey data has been collected yet

1 consumer reported time for results

To what extent do I have to use Depiwhite before I begin to see changes in my health conditions?
As part of the reports released by website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Depiwhite. To get the time effectiveness of using Depiwhite drug by other patients, please click here.
1 day1

2 consumers reported age


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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