What is Duac 10 mg/g+50 mg/g?
Duac 10 mg/g+50 mg/g and Clindamycin (Duac 10 mg/g+50 mg/g) combination is used to treat acne. It works by killing the bacteria that cause acne and by keeping the skin pores clean (tiny openings on the skin).
This medicine is available only with your doctor's prescription.
Duac 10 mg/g+50 mg/g indications
Duac 10 mg/g+50 mg/g Gel is indicated for the topical treatment of mild to moderate acne vulgaris, particularly inflammatory lesions, in adults and adolescents aged 12 years and above.
Duac 10 mg/g+50 mg/g description
Duac 10 mg/g+50 mg/g gel contains Clindamycin (Duac 10 mg/g+50 mg/g) (as 1.2% Clindamycin (Duac 10 mg/g+50 mg/g) phosphate) at a concentration equivalent to 1% w/w (10 mg/g) and Duac 10 mg/g+50 mg/g 5% w/w (50 mg/g).
Excipients/Inactive Ingredients: Carbomer (50000 mPa·s), Dimeticone (100 mm2·s-1), Disodium Lauryl Sulfosuccinate, Disodium Edetate, Glycerol, Silica, Colloidal Hydrated, Poloxamer 182, Purified Water, Sodium Hydroxide.
Duac 10 mg/g+50 mg/g dosage
For cutaneous use only.
Adults and Adolescents (aged 12 years and above): Duac 10 mg/g+50 mg/g Gel should be applied once daily in the evening, to the entire affected area.
Patients should be advised that excessive application will not improve efficacy, but may increase the risk of skin irritation. If excessive dryness or peeling occurs, frequency of application should be reduced or application temporarily interrupted.
An effect on inflammatory and non-inflammatory lesions may be seen as early as week 2-5 of treatment.
The safety and efficacy of Duac 10 mg/g+50 mg/g Gel has not been studied beyond 12 weeks in acne vulgaris clinical trials. Treatment with Duac 10 mg/g+50 mg/g Gel should not exceed more than 12 weeks of continuous use.
Paediatric Population: The safety and efficacy of Duac 10 mg/g+50 mg/g Gel has not been established in children under 12 years of age, therefore Duac 10 mg/g+50 mg/g Gel is not recommended for use in this population.
Elderly Patients: No specific recommendations.
Administration: Duac 10 mg/g+50 mg/g Gel should be applied in a thin film after washing gently with a mild cleanser and fully drying. If the gel does not rub into the skin easily, too much is being applied.
Hands should be washed after application.
Duac 10 mg/g+50 mg/g interactions
No formal drug-drug interaction studies have been performed with Duac 10 mg/g+50 mg/g Gel.
Concomitant topical antibiotics, medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol and/or astringents, should be used with caution as a cumulative irritant effect may occur.
Duac 10 mg/g+50 mg/g Gel should not be used in combination with erythromycin-containing products due to possible antagonism to the Clindamycin (Duac 10 mg/g+50 mg/g) component.
Clindamycin (Duac 10 mg/g+50 mg/g) has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore caution should be exercised with concomitant use.
Concomitant application of Duac 10 mg/g+50 mg/g Gel with tretinoin, isotretinoin and tazarotene should be avoided since Duac 10 mg/g+50 mg/g may reduce their efficacy and increase irritation. If combination treatment is required, the products should be applied at different times of the day (e.g. one in the morning and the other in the evening).
Using topical Duac 10 mg/g+50 mg/g-containing preparations at the same time as topical sulphonamide-containing products may cause skin and facial hair to temporarily change colour (yellow/orange).
Duac 10 mg/g+50 mg/g side effects
See also:
What are the possible side effects of Duac 10 mg/g+50 mg/g?
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Itching (pruritus)
Dry skin
Skin redness
Skin tingling
The side effects listed above may not include all of the side effects reported by the drug’s manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Tell your doctor if you do not feel well while
you are using Duac 10 mg/g+50 mg/g Gel.
Duac 10 mg/g+50 mg/g Gel helps most people with
acne but it may have unwanted side effects in a
few people.
All medicines can have side effects. Sometimes
they are serious, most of the time they are not.
You may need medical treatment if you get some
of these side effects.
The gel may cause slight itching and burning
and make your skin feel warm, especially
when it is first applied. You may also notice
flaking and redness of your skin during the
first few weeks of use. These effects are
normal; if they bother you, try using the
product less often for a while, or stop for a few
days and start again.
If you suffer severe burning, peeling or
itching, or other effects not mentioned in this
leaflet, you should stop using Duac 10 mg/g+50 mg/g
Gel and go back to your doctor for advice.
Duac 10 mg/g+50 mg/g contraindications
Duac 10 mg/g+50 mg/g Gel must not be administered to patients with known hypersensitivity to Clindamycin (Duac 10 mg/g+50 mg/g), lincomycin, Duac 10 mg/g+50 mg/g, or any of the excipients in the formulation.
Active ingredient matches for Duac 10 mg/g+50 mg/g:
Benzoyl Peroxide/Clindamycin in Hungary.
Benzoyl Peroxide in Germany.
List of Duac 10 mg/g+50 mg/g substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Duac Once Daily (Hong Kong, Taiwan, Tunisia, United Kingdom) | |
| Duac Once Daily topical gel 25 g x 1's (Stiefel) | |
| Duo Clindacin (Argentina) | |
| Duosight (Mexico) | |
| Duresthin 5 | |
| Eclaran (Czech Republic, France, Luxembourg, Portugal, Tunisia, Vietnam) | |
| Gel; Topical; Benzoyl Peroxide 10% (Pierre fabre) | |
| Gel; Topical; Benzoyl Peroxide 5% (Pierre fabre) | |
| Eclaran 5 (Vietnam) | |
| Eclaran 5 5 % x 1 tube 45 g | |
| Ecnagel P.B. (Argentina) | |
| Ecnagel PB (Argentina) | |
| Ecuaderm (Venezuela) | |
| Effaclar Duo (United States) | |
| Effacné (France) | |
| Gel; Topical; Benzoyl Peroxide 2.5% | |
| Gel; Topical; Benzoyl Peroxide 5% | |
| Effacne (Switzerland, France) | |
| Gel; Topical; Benzoyl Peroxide 2.5% (Roche-posay) | |
| Gel; Topical; Benzoyl Peroxide 5% (Roche-posay) | |
| Effacné (France) | |
| Gel; Topical; Benzoyl Peroxide 2.5% | |
| Gel; Topical; Benzoyl Peroxide 5% | |
| Effacné 5% (France) | |
| Eloxyl | |
| Emergency Acne Vanishing (Canada) | |
| Emergency Acne Vanishing Facial Cleanser | |
| Lotion; Topical; Benzoyl Peroxide 5% | |
| Enzoxid (Thailand) | |
| Enzoxid 2.5 % x 20 g x 1's | |
| Enzoxid 2.5 % x 12's | |
| Enzoxid 5 % x 20 g x 1's | |
| Enzoxid 5 % x 12's | |
| Epi Clear Antiseptic Lotion | |
| Epi-Clear | |
| EthexDERM BPW Topical | |
| Fatroxid (Portugal) | |
| Fostex Benzoyl Peroxide Topical | |
| Freshlook (Bangladesh) | |
| Garox | |
| H2 Oxyl | |
| Cream; Topical; Benzoyl Peroxide 10% | |
| Cream; Topical; Benzoyl Peroxide 20% | |
| Cream; Topical; Benzoyl Peroxide 5% | |
| H2Oxyl | |
| Cream; Topical; Benzoyl Peroxide 2.5% | |
| Incidol | |
| Indoxyl (Austria, Bangladesh, Colombia, Greece, Mexico, Peru) | |
| Gel; Topical; Benzoyl Peroxide 5%; Clindamycin Phosphate 1% (Gabriel) | |
| Indoxyl 10 mg/g + 50 mg/g (Austria) | |
| Inoxitan (Czech Republic) | |
| Johnson's Clean and Clear Persa-Gel | |
| Lotion; Topical; Benzoyl Peroxide 5% | |
| Johnsons Clean & Clear Persa Gel | |
See 793 substitutes for Duac 10 mg/g+50 mg/g | |
References
- DailyMed. "BENZOYL PEROXIDE; ERYTHROMYCIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "BENZOYL PEROXIDE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "clindamycin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Duac 10 mg/g+50 mg/g are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Duac 10 mg/g+50 mg/g. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
