What is Duac Once Daily?
Benzoyl Peroxide (Duac Once Daily) and Clindamycin (Duac Once Daily) combination is used to treat acne. It works by killing the bacteria that cause acne and by keeping the skin pores clean (tiny openings on the skin).
This medicine is available only with your doctor's prescription.
Duac Once Daily indications
Duac Once Daily Gel is indicated for the topical treatment of mild to moderate acne vulgaris, particularly inflammatory lesions, in adults and adolescents aged 12 years and above.
Duac Once Daily description
Duac Once Daily gel contains Clindamycin (Duac Once Daily) (as 1.2% Clindamycin (Duac Once Daily) phosphate) at a concentration equivalent to 1% w/w (10 mg/g) and Benzoyl Peroxide (Duac Once Daily) 5% w/w (50 mg/g).
Excipients/Inactive Ingredients: Carbomer (50000 mPa·s), Dimeticone (100 mm2·s-1), Disodium Lauryl Sulfosuccinate, Disodium Edetate, Glycerol, Silica, Colloidal Hydrated, Poloxamer 182, Purified Water, Sodium Hydroxide.
Duac Once Daily dosage
For cutaneous use only.
Adults and Adolescents (aged 12 years and above): Duac Once Daily Gel should be applied once daily in the evening, to the entire affected area.
Patients should be advised that excessive application will not improve efficacy, but may increase the risk of skin irritation. If excessive dryness or peeling occurs, frequency of application should be reduced or application temporarily interrupted.
An effect on inflammatory and non-inflammatory lesions may be seen as early as week 2-5 of treatment.
The safety and efficacy of Duac Once Daily Gel has not been studied beyond 12 weeks in acne vulgaris clinical trials. Treatment with Duac Once Daily Gel should not exceed more than 12 weeks of continuous use.
Paediatric Population: The safety and efficacy of Duac Once Daily Gel has not been established in children under 12 years of age, therefore Duac Once Daily Gel is not recommended for use in this population.
Elderly Patients: No specific recommendations.
Administration: Duac Once Daily Gel should be applied in a thin film after washing gently with a mild cleanser and fully drying. If the gel does not rub into the skin easily, too much is being applied.
Hands should be washed after application.
Duac Once Daily interactions
No formal drug-drug interaction studies have been performed with Duac Once Daily Gel.
Concomitant topical antibiotics, medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol and/or astringents, should be used with caution as a cumulative irritant effect may occur.
Duac Once Daily Gel should not be used in combination with erythromycin-containing products due to possible antagonism to the Clindamycin (Duac Once Daily) component.
Clindamycin (Duac Once Daily) has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore caution should be exercised with concomitant use.
Concomitant application of Duac Once Daily Gel with tretinoin, isotretinoin and tazarotene should be avoided since Benzoyl Peroxide (Duac Once Daily) may reduce their efficacy and increase irritation. If combination treatment is required, the products should be applied at different times of the day (e.g. one in the morning and the other in the evening).
Using topical Benzoyl Peroxide (Duac Once Daily)-containing preparations at the same time as topical sulphonamide-containing products may cause skin and facial hair to temporarily change colour (yellow/orange).
Duac Once Daily side effects
See also:
What are the possible side effects of Duac Once Daily?
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Itching (pruritus)
Dry skin
Skin redness
Skin tingling
The side effects listed above may not include all of the side effects reported by the drug’s manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Tell your doctor if you do not feel well while
you are using Duac Once Daily Gel.
Duac Once Daily Gel helps most people with
acne but it may have unwanted side effects in a
few people.
All medicines can have side effects. Sometimes
they are serious, most of the time they are not.
You may need medical treatment if you get some
of these side effects.
The gel may cause slight itching and burning
and make your skin feel warm, especially
when it is first applied. You may also notice
flaking and redness of your skin during the
first few weeks of use. These effects are
normal; if they bother you, try using the
product less often for a while, or stop for a few
days and start again.
If you suffer severe burning, peeling or
itching, or other effects not mentioned in this
leaflet, you should stop using Duac Once Daily
Gel and go back to your doctor for advice.
Duac Once Daily contraindications
Duac Once Daily Gel must not be administered to patients with known hypersensitivity to Clindamycin (Duac Once Daily), lincomycin, Benzoyl Peroxide (Duac Once Daily), or any of the excipients in the formulation.
Active ingredient matches for Duac Once Daily:
Benzoyl Peroxide/Clindamycin in Hong Kong, Taiwan, Tunisia, United Kingdom.
Benzoyl peroxide/clindamycin phosphate in United Kingdom.
Benzoyl peroxide 5%/Clindamycin 1% in Hongkong.
| Unit description / dosage (Manufacturer) | Price, USD |
| Gel; Topical; Benzoyl Peroxide, Hydrous 5%; Clindamycin Phosphate 1% | |
| Duac Once Daily 6 g | |
| Duac Once Daily 25 g | |
| Duac Once Daily topical gel 5 g x 1's (Stiefel) | |
| Duac Once Daily topical gel 25 g x 1's (Stiefel) | |
List of Duac Once Daily substitutes (brand and generic names): | |
| Clindapack (Mexico) | |
| Gel; Topical; Benzoyl Peroxide 2.5%; Clindamycin Phosphate 0.5% (Darier) | |
| Clindoxyl (Argentina, Canada, Denmark, Finland, Turkey) | |
| Gel; Topical; Benzoyl Peroxide 5%; Clindamycin Phosphate 1% (Glaxo Smithkline Pharmaceuticals Ltd.) | |
| 10g (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| Clindoxyl Clindamycin phosphate 1 % w/w, Benzoyl peroxide 1 % w/w. GEL / 10g (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| Clindoxyl 10 gm Gel (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| CLINDOXYL GEL 1 tube / 10 GM gel each (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| CLINDOXYL topical gel 10g (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| Clindoxyl Gel (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| Clindoxyl ADV (Canada) | |
| Clindoxyl Once Daily (Singapore) | |
| Clindoxyl Once Daily 10 g x 1's (GlaxoSmithKline) | |
| Clindoxyl Once Daily 25 g x 1's (GlaxoSmithKline) | |
| Clindoxyl Once Daily topical gel 15 g x 1's (GlaxoSmithKline) | |
| Clindoxyl Once Daily topical gel 25 g x 1's (GlaxoSmithKline) | |
| Clinoper (Turkey) | |
| Clinred-B (India) | |
| Clinred-B Clindamycin phosphate 1 %, benzoyl peroxide 5 %. CRM / 15g (Encore) | $ 2.40 |
| CLINRED-B cream 15g (Encore) | $ 2.40 |
| CP Acne Duo (Argentina) | |
| CP-Acne (Argentina) | |
| Dettonant (Argentina) | |
| Duac 10 mg/g+50 mg/g (Germany, Hungary) | |
| DUAC 10mg/g + 30mg/g (Germany) | |
| Duac Acne (Netherlands) | |
| DUAC Akne (Germany) | |
| Duac Care System | |
| Duac Once Daily Gel (Thailand) | |
| Duac Once Daily Gel topical gel 10 g x 1's (Stiefel) | |
| Duac Once Daily Gel topical gel 25 g x 1's (Stiefel) | |
| Duac Topical Gel | |
| Duo Clindacin (Argentina) | |
| Duosight (Mexico) | |
| Indoxyl (Austria, Bangladesh, Colombia, Greece, Mexico, Peru) | |
| Gel; Topical; Benzoyl Peroxide 5%; Clindamycin Phosphate 1% (Gabriel) | |
| Indoxyl 10 mg/g + 50 mg/g (Austria) | |
| Oximin (Turkey) | |
| OXIMIN cap 10's (Tulip) | |
| PERCLIN (Argentina) | |
| 5 % x 30g (Affy) | $ 0.66 |
| Perclin 5% CRM / 30g (Affy) | $ 0.66 |
| PERCLIN cream 5 % x 30g (Affy) | $ 0.66 |
| Perclin 5% CRM / 30g (Affy) | $ 0.66 |
| Peroxiclin Duo (Argentina) | |
| Septigel (Guatemala) | |
| Stiefel Indoxyl (Chile) | |
| Taro-Benzoyl Peroxide/Clindamycin (Canada) | |
| Taro-Clindamycin/Benzoyl Peroxide (Canada) | |
See 68 substitutes for Duac Once Daily | |
References
- DailyMed. "BENZOYL PEROXIDE; ERYTHROMYCIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "BENZOYL PEROXIDE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "clindamycin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Duac Once Daily are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Duac Once Daily. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported useful
Was the Duac Once Daily drug useful in terms of decreasing the symptom or the disease?According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
| Users | % | ||
|---|---|---|---|
| Useful | 1 | 100.0% | |
1 consumer reported price estimates
Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Duac Once Daily drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
| Users | % | ||
|---|---|---|---|
| Not expensive | 1 | 100.0% | |
1 consumer reported time for results
To what extent do I have to use Duac Once Daily before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Duac Once Daily. To get the time effectiveness of using Duac Once Daily drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| 1 day | 1 | 100.0% | |
5 consumers reported age
| Users | % | ||
|---|---|---|---|
| 16-29 | 5 | 100.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
