What is Duo Clindacin?
Benzoyl Peroxide (Duo Clindacin) and Clindamycin (Duo Clindacin) combination is used to treat acne. It works by killing the bacteria that cause acne and by keeping the skin pores clean (tiny openings on the skin).
This medicine is available only with your doctor's prescription.
Duo Clindacin indications
Duo Clindacin Gel is indicated for the topical treatment of mild to moderate acne vulgaris, particularly inflammatory lesions, in adults and adolescents aged 12 years and above.
Duo Clindacin description
Duo Clindacin gel contains Clindamycin (Duo Clindacin) (as 1.2% Clindamycin (Duo Clindacin) phosphate) at a concentration equivalent to 1% w/w (10 mg/g) and Benzoyl Peroxide (Duo Clindacin) 5% w/w (50 mg/g).
Excipients/Inactive Ingredients: Carbomer (50000 mPa·s), Dimeticone (100 mm2·s-1), Disodium Lauryl Sulfosuccinate, Disodium Edetate, Glycerol, Silica, Colloidal Hydrated, Poloxamer 182, Purified Water, Sodium Hydroxide.
Duo Clindacin dosage
For cutaneous use only.
Adults and Adolescents (aged 12 years and above): Duo Clindacin Gel should be applied once daily in the evening, to the entire affected area.
Patients should be advised that excessive application will not improve efficacy, but may increase the risk of skin irritation. If excessive dryness or peeling occurs, frequency of application should be reduced or application temporarily interrupted.
An effect on inflammatory and non-inflammatory lesions may be seen as early as week 2-5 of treatment.
The safety and efficacy of Duo Clindacin Gel has not been studied beyond 12 weeks in acne vulgaris clinical trials. Treatment with Duo Clindacin Gel should not exceed more than 12 weeks of continuous use.
Paediatric Population: The safety and efficacy of Duo Clindacin Gel has not been established in children under 12 years of age, therefore Duo Clindacin Gel is not recommended for use in this population.
Elderly Patients: No specific recommendations.
Administration: Duo Clindacin Gel should be applied in a thin film after washing gently with a mild cleanser and fully drying. If the gel does not rub into the skin easily, too much is being applied.
Hands should be washed after application.
Duo Clindacin interactions
No formal drug-drug interaction studies have been performed with Duo Clindacin Gel.
Concomitant topical antibiotics, medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol and/or astringents, should be used with caution as a cumulative irritant effect may occur.
Duo Clindacin Gel should not be used in combination with erythromycin-containing products due to possible antagonism to the Clindamycin (Duo Clindacin) component.
Clindamycin (Duo Clindacin) has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore caution should be exercised with concomitant use.
Concomitant application of Duo Clindacin Gel with tretinoin, isotretinoin and tazarotene should be avoided since Benzoyl Peroxide (Duo Clindacin) may reduce their efficacy and increase irritation. If combination treatment is required, the products should be applied at different times of the day (e.g. one in the morning and the other in the evening).
Using topical Benzoyl Peroxide (Duo Clindacin)-containing preparations at the same time as topical sulphonamide-containing products may cause skin and facial hair to temporarily change colour (yellow/orange).
Duo Clindacin side effects
See also:
What are the possible side effects of Duo Clindacin?
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Itching (pruritus)
Dry skin
Skin redness
Skin tingling
The side effects listed above may not include all of the side effects reported by the drug’s manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Tell your doctor if you do not feel well while
you are using Duo Clindacin Gel.
Duo Clindacin Gel helps most people with
acne but it may have unwanted side effects in a
few people.
All medicines can have side effects. Sometimes
they are serious, most of the time they are not.
You may need medical treatment if you get some
of these side effects.
The gel may cause slight itching and burning
and make your skin feel warm, especially
when it is first applied. You may also notice
flaking and redness of your skin during the
first few weeks of use. These effects are
normal; if they bother you, try using the
product less often for a while, or stop for a few
days and start again.
If you suffer severe burning, peeling or
itching, or other effects not mentioned in this
leaflet, you should stop using Duo Clindacin
Gel and go back to your doctor for advice.
Duo Clindacin contraindications
Duo Clindacin Gel must not be administered to patients with known hypersensitivity to Clindamycin (Duo Clindacin), lincomycin, Benzoyl Peroxide (Duo Clindacin), or any of the excipients in the formulation.
Active ingredient matches for Duo Clindacin:
Benzoyl Peroxide/Clindamycin/Gel, benzoyl peroxide/topical solution, clindamycin phosphate in Argentina.
List of Duo Clindacin substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Clindamycin/Benzoyl Peroxide (Vietnam) | |
| Clindamycin/Benzoyl Peroxide Gel | |
| Clindamycin/Benzoyl Peroxide Mylan (United States) | |
| Clindapack (Mexico) | |
| Gel; Topical; Benzoyl Peroxide 2.5%; Clindamycin Phosphate 0.5% (Darier) | |
| Clindoxyl (Argentina, Canada, Denmark, Finland, Turkey) | |
| Gel; Topical; Benzoyl Peroxide 5%; Clindamycin Phosphate 1% (Glaxo Smithkline Pharmaceuticals Ltd.) | |
| 10g (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| Clindoxyl Clindamycin phosphate 1 % w/w, Benzoyl peroxide 1 % w/w. GEL / 10g (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| Clindoxyl 10 gm Gel (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| CLINDOXYL GEL 1 tube / 10 GM gel each (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| CLINDOXYL topical gel 10g (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| Clindoxyl Gel (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 4.82 |
| Clindoxyl ADV (Canada) | |
| Clinoper (Turkey) | |
| Clinred-B (India) | |
| Clinred-B Clindamycin phosphate 1 %, benzoyl peroxide 5 %. CRM / 15g (Encore) | $ 2.40 |
| CLINRED-B cream 15g (Encore) | $ 2.40 |
| CP Acne Duo (Argentina) | |
| CP-Acne (Argentina) | |
| Dettonant (Argentina) | |
| Duac 10 mg/g+50 mg/g (Germany, Hungary) | |
| DUAC 10mg/g + 30mg/g (Germany) | |
| Duac Acne (Netherlands) | |
| DUAC Akne (Germany) | |
| Duac Care System | |
| Duac Once Daily (Hong Kong, Taiwan, Tunisia, United Kingdom) | |
| Gel; Topical; Benzoyl Peroxide, Hydrous 5%; Clindamycin Phosphate 1% (Stiefel) | |
| Duac Once Daily 6 g (Stiefel) | |
| Duac Once Daily 25 g (Stiefel) | |
| Duac Once Daily topical gel 5 g x 1's (Stiefel) | |
| Duac Once Daily topical gel 25 g x 1's (Stiefel) | |
| Duosight (Mexico) | |
| Indoxyl (Austria, Bangladesh, Colombia, Greece, Mexico, Peru) | |
| Gel; Topical; Benzoyl Peroxide 5%; Clindamycin Phosphate 1% (Gabriel) | |
| Indoxyl 10 mg/g + 50 mg/g (Austria) | |
| Oximin (Turkey) | |
| OXIMIN cap 10's (Tulip) | |
| PERCLIN (Argentina) | |
| 5 % x 30g (Affy) | $ 0.66 |
| Perclin 5% CRM / 30g (Affy) | $ 0.66 |
| PERCLIN cream 5 % x 30g (Affy) | $ 0.66 |
| Perclin 5% CRM / 30g (Affy) | $ 0.66 |
| Peroxiclin Duo (Argentina) | |
| Septigel (Guatemala) | |
| Stiefel Indoxyl (Chile) | |
| Taro-Benzoyl Peroxide/Clindamycin (Canada) | |
| Taro-Clindamycin/Benzoyl Peroxide (Canada) | |
See 61 substitutes for Duo Clindacin | |
References
- DailyMed. "BENZOYL PEROXIDE; ERYTHROMYCIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "BENZOYL PEROXIDE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "clindamycin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Duo Clindacin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Duo Clindacin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
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Information checked by Dr. Sachin Kumar, MD Pharmacology
