Gababit-MN indications
Pernicious anemia, both uncomplicated and accompanied by nervous system involvement.
Dietary deficiency of Vitamin B12, occurring in strict vegetarians and in their breast-fed infants. (Isolated vitamin B12 deficiency is very rare).
Malabsorption of vitamin B12, resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates vitamin B12 absorption. These conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). Folate deficiency in these patients is usually more severe than vitamin B12 deficiency.
Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). Total gastrectomy always produces vitamin B12 deficiency.
Structural lesions leading to vitamin B12 deficiency include regional ileitis, ileal resections, malignancies, etc.
Competition for Vitamin B12 by intestinal parasites or bacteria.
The fish tapeworm (Diphyilobothrium latum) absorbs huge quantities of vitamin B12 and infested patients often have associated gastric atrophy. The blind-loop syndrome may produce deficiency of Vitamin B12 or folate.
Inadequate utilization of vitamin B12. This may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia.
For the Schilling Test.
Gababit-MN description
Gababit-MN/Gababit-MN-1500 also contains the following inactive ingredients: Lactose, maize starch, microcrystalline cellulose, povidone (K-30), purified talc, anhydrous colloidal silica, hypromellose, macrogol, titanium dioxide, isopropyl alcohol, dicholoromethane, red iron oxide and yellow iron oxide.
Gababit-MN dosage
Gababit-MN: The daily dose is 1 tab 3 times daily.
Gababit-MN-1500: The daily dose is 1 tab once daily. The dosage should be adjusted according to age of patient and severity of symptoms.
Gababit-MN interactions
Antibiotics: The use of antibiotics may alter the intestinal microflora and may decrease the possible contribution of Gababit-MN by certain inhabitants of the microflora (eg, Lactobacillus spp) to the body's requirement for the vitamin. This may particularly be a problem for vegetarians. Garlic, onions, leeks, bananas, asparagus and artichokes, among other vegetables and fruits, contain inulins which promote the growth of certain colonic bacteria including Lactobacillus spp. Cholestyramine:
Colchicine: Colchicine may cause decreased absorption of Gababit-MN. Colestipol:
H2-Blockers (Cimetidine, Famotidine, Nizatidine, Ranitidine): Chronic use of H2-blockers may result to decreased absorption of Gababit-MN. They are unlikely to affect the absorption of supplemental B12.
Metformin: Metformin may decrease the absorption of Gababit-MN. This possible effect may be reversed with oral calcium supplementation.
Nitrous Oxide: Inhalation of the anesthetic agent nitrous oxide (not to be confused with nitric oxide) can produce a functional deficiency. Nitrous oxide forms a complex with cobalt in Gababit-MN, the cofactor for methionine synthase, resulting in inactivation of the enzyme.
Para-Amino Salicylic Acid: Chronic use of the anti-tuberculosis drug may decrease the absorption of Gababit-MN.
Potassium Chloride: It has been reported that potassium chloride may decrease the absorption of Gababit-MN.
Proton Pump Inhibitors (Lansoprazole, Omeprazole, Pantoprazole, Rabeprazole): Chronic use of proton pump inhibitors may result in decreased absorption, naturally found in food sources.
Gababit-MN side effects
water weight gain, edema, increase in BUN, and dilutional hyponatremia. Asterixis was reported to have worsened in one patient during infusion of this medicine.
Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.
Symptoms may result from an excess or deficit of one or more of the ions present in the solution; therefore, frequent monitoring of electrolyte levels is essential.
Phosphorus deficiency may lead to impaired tissue oxygenation and acute hemolytic anemia. Relative to calcium, excessive phosphorus intake can precipitate hypocalcemia with cramps, tetany and muscular hyperexcitability.
If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.
Gababit-MN contraindications
Hypersensitivity to Gababit-MN or other vit B12-containing, cobalamin products or cobalt.
Active ingredient matches for Gababit-MN:
Mecobalamin in India.
Gabapentin in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| Gababit-MN Methylcobalamin 1500 mcg, Gabapentin 300 mg. TAB / 10 | |
| 10's | |
| GABABIT-MN tab 10's (Cubit) | |
List of Gababit-MN substitutes (brand and generic names): | |
| Gaba-M (India) | |
| GABA-M tab 10's (Andic) | |
| GABACAP (India) | |
| 300 mg x 10's (Zydus (Neuro)) | $ 1.19 |
| Gabacap 300mg CAP / 10 (Zydus (Neuro)) | $ 1.19 |
| GABACAP 100 MG CAPSULE 1 strip / 10 capsules each (Zydus (Neuro)) | $ 0.45 |
| GABACAP 300 MG CAPSULE 1 strip / 10 capsules each (Zydus (Neuro)) | $ 1.19 |
| GABACAP cap 300 mg x 10's (Zydus (Neuro)) | $ 1.19 |
| Gabacap 300mg CAP / 10 (Zydus (Neuro)) | $ 1.19 |
| Gabacap 100mg Capsule (Zydus (Neuro)) | $ 0.04 |
| Gabacap 300mg Capsule (Zydus (Neuro)) | $ 0.12 |
| Gabacent (India) | |
| Gabacent 100mg TAB / 10 (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 0.49 |
| Gabacent 300mg TAB / 10 (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 1.28 |
| 100 mg x 10's (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 0.49 |
| 300 mg x 10's (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 1.28 |
| Gabacent 300 mg Tablet (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 0.13 |
| Gabacent 100 mg Tablet (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 0.05 |
| GABACENT 100MG TABLET 1 strip / 10 tablets each (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 0.47 |
| GABACENT 300MG TABLET 1 strip / 10 tablets each (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 1.75 |
| GABACENT tab 100 mg x 10's (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 0.49 |
| GABACENT tab 300 mg x 10's (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 1.28 |
| Gabacent 100mg Tablet (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 0.05 |
| Gabacent 300mg Tablet (Crescent Formulations Pvt Ltd (Crescent Therapeutics Ltd. )) | $ 0.17 |
| GABACIP | |
| GABACIP 300 MG CAPSULE 1 strip / 10 capsules each (Cipla Ltd) | $ 1.20 |
| Gabacip 300mg Capsule (Cipla Ltd) | $ 0.12 |
| Gabaciz (India) | |
| Gabaciz 100mg TAB / 10 (Invision Medi Sciences) | $ 0.54 |
| 100 mg x 10's (Invision Medi Sciences) | $ 0.54 |
| Gabaciz 100 mg Tablet (Invision Medi Sciences) | $ 0.05 |
| GABACIZ tab 100 mg x 10's (Invision Medi Sciences) | $ 0.54 |
| Gabaciz M | |
| Gabaciz M 100 mg+500 mcg Tablet (Invision Medi Sciences) | $ 0.12 |
| Gabacor (Australia) | |
| Gabacord M | |
| Gabacord M 300 mg+500 mcg Tablet (Accord Pharmaceuticals) | $ 0.13 |
| GABADAY (India) | |
| GABADAY tab 100 mg x 10's (Invision) | $ 0.60 |
| Gabadin 300mg (Paraguay) | |
| Gabadin 400mg (Paraguay) | |
| Gabadin 600mg (Paraguay) | |
| Gabadin 800mg (Paraguay) | |
| Gabadoz (Denmark) | |
| Tablet, Film-Coated; Oral; Gabapentin 600 mg | |
| Tablets, Film-Coated; Oral; Gabapentin 600 mg | |
| Gabafine (India) | |
| Gabafine 300mg CAP / 10 (Finecure) | |
| GABAFINE cap 300 mg x 10's (Finecure) | |
| Gabafix (Pakistan) | |
| Gabagamma (Bulgaria, Czech Republic, Estonia, Georgia, Germany, Hungary, Latvia, Lithuania, Poland, Romania, Russian Federation, Serbia, Slovakia, Slovenia) | |
| Capsule; Oral; Gabapentin 100 mg (Worwag pharma) | |
| Capsule; Oral; Gabapentin 300 mg (Worwag pharma) | |
See 4158 substitutes for Gababit-MN | |
References
- DailyMed. "GABAPENTIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "gabapentin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "gabapentin". http://www.drugbank.ca/drugs/DB00996 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Gababit-MN are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Gababit-MN. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet1 consumer reported age
| Users | % | ||
|---|---|---|---|
| 16-29 | 1 | 100.0% | |
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Information checked by Dr. Sachin Kumar, MD Pharmacology
