Jodipro Plus Uses

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What is Jodipro Plus?

There are many brands and forms of povidone Jodipro Plus topical available. Not all brands are listed on this leaflet.

Jodipro Plus is used on the skin to treat or prevent skin infection in minor cuts, scrapes, or burns. Jodipro Plus is also used in a medical setting to help prevent infection and promote healing in skin wounds, pressure sores, or surgical incisions.

Some forms of povidone Jodipro Plus topical are used inside the mouth to provide temporary relief of minor mouth pain or irritation, sore throat, or canker sore pain.

Jodipro Plus may also be used for purposes not listed in this medication guide.

Jodipro Plus indications

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Intramuscular

Jodipro Plus deficiency disorders

Adult: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Jodipro Plus): Up to 45 yr: 380 mg Jodipro Plus, as single IM doses to provide adequate protection from Jodipro Plus deficiency for up to 3 yr. Pregnant patient: Moderate to severe: 480 mg Jodipro Plus each yr.

Child: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Jodipro Plus): 380 mg Jodipro Plus, as single IM doses to provide adequate protection from Jodipro Plus deficiency for up to 3 yr. Infants up to 1 yr: 190 mg Jodipro Plus, as iodised oil (480 mg/ml Jodipro Plus).

Oral

Grave's disease

Child: Neonates: 1 drop of strong Jodipro Plus solution every 8 hr.

Oral

Radiation protection against radioactive Jodipro Plus

Adult: As potassium iodide: 100-150 mg 24 hr before procedure and daily for up to 10 days after procedure.

Child: As potassium iodide: Infants from birth to 1 mth with a predicted thyroid exposure of ≥5 centigrays (cGy): 16 mg. >1 mth to 3 yr with a predicted thyroid exposure of ≥5 cGy: 32 mg. >3 yr to 18 yr (except adolescents approaching adult size) with a predicted thyroid exposure of ≥5 cGy: 65 mg. Do not exceed once-daily doses.

Oral

Preoperative reduction of vascularity of the thyroid gland

Adult: As potassium iodide: 50-250 mg (approx 1-5 drops of a solution containing 1 g/ml) tid for 10-14 days before surgery.

Child: As potassium iodide: 50-250 mg (approx 1-5 drops of a solution containing 1 g/ml) tid for 10-14 days before surgery. As strong Jodipro Plus solution: 0.1-0.3 ml (or approx 3-5 drops) tid.

Oral

Cutaneous or lymphocutaneous sporotrichosis

Adult: As potassium iodide solution containing 1 g/mL: Initially, 1 mL tid, should continue for at least 1 mth after disappearance or stabilisation of the lesions.

Child: As potassium iodide: Initially, 250 mg (approx 5 drops of a solution containing 1 g/ml) tid. Max: 1.25-2 g (approx 25-40 drops) tid. Duration: 3-6 mth.

Oral

Thyroid storm

Adult: As potassium iodide: Up to 500 mg every 4 hr.

Oral

Jodipro Plus deficiency disorders

Adult: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Jodipro Plus): 400 mg Jodipro Plus once yrly. Pregnant patient: 200 mg Jodipro Plus as a single dose. Moderate to severe: 300-480 mg Jodipro Plus each yr or 100-300 mg Jodipro Plus every 6 mth and for at least 1 yr postpartum.

Child: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Jodipro Plus): Infants up to 1 yr: Single dose of 100 mg Jodipro Plus; 1-5 yr: 200 mg Jodipro Plus; >6 yr: 400 mg Jodipro Plus.

Topical/Cutaneous

Cleaning wet ulcers and wounds

Adult: As 0.9% topical gel: Apply to clean wound. Max: 50 g/application and 150 g/wk. Change dressing about 3 times/wk and reduce applications as exudate decreases. Do not use for >3 mth and stop treatment when wound is free of exudate.

Child: As 0.9% topical gel: Apply to clean wound. Max: 50 g/application and 150 g/wk. Change dressing about 3 times/wk and reduce applications as exudate decreases. Do not use for >3 mth and stop treatment when wound is free of exudate.

Topical/Cutaneous

Minor, superficial skin wounds

Adult: As 2% or 2.5% solution/ointment: Apply small amount to the affected area 1-3 times daily.

Child: As 2% or 2.5% solution/ointment: Apply small amount to the affected area 1-3 times daily.

How should I use Jodipro Plus?

Use exactly as directed on the label, or as prescribed by your doctor.

Jodipro Plus is available in many different forms, such as a liquid, ointment, aerosol powder, cream, spray, swab, and soap. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Always follow directions on the medicine label about using this medicine on a child. Some forms of povidone Jodipro Plus topical should not be used in children of certain ages.

Jodipro Plus is usually applied to the skin as needed. First clean the area to be treated.

Shake Jodipro Plus spray well just before each use.

Allow the medicine to dry completely on the skin before applying a bandage. Do not apply a tight bandage.

Do not use this medicine on deep wounds, puncture wounds, animal bites, or serious burns. Do not apply over large skin areas.

When treating an infection, you may be given antibiotic medication to take by mouth. Use all medicines for the full prescribed length of time, even if your symptoms quickly improve.

Jodipro Plus used in the mouth may be used up to 4 times per day. How often you can use this medicine depends on what form you use. Follow all directions on the medicine label.

Do not use Jodipro Plus in the mouth if you are using a form that is made for use only on the skin.

To use Jodipro Plus spray in the mouth, spray directly into the mouth or throat. Leave the medicine in place for 15 seconds, then spit it out. Avoid swallowing the spray. Use once every 2 hours as needed.

To use Jodipro Plus as a mouth rinse, gargle or swish the liquid for 30 seconds, then spit it out. Do not swallow the liquid. Use up to 4 times per day.

You should not use Jodipro Plus for longer than 7 days without medical advice.

Call your doctor if your sore throat is severe or ongoing after 2 days, or if you also have a high fever, headache, nausea, and vomiting.

If you are using Jodipro Plus on your skin, seek medical advice if you have new or worsening symptoms of pain, redness, swelling, rash, or fever.

Store at room temperature away from moisture and heat. Do not freeze.

Each Jodipro Plus swab is for one use only.

Jodipro Plus can stain skin, teeth, and fabric. You may use rubbing alcohol to remove staining from your skin. Avoid getting alcohol onto a wound or irritated skin. Stains on fabric can be removed by rinsing with ammonia diluted with water. Avoid getting the medicine on jewelry, especially silver.

Jodipro Plus spray is flammable. Do not use near high heat or open flame. Do not smoke until the gel has completely dried on your skin.

Uses of Jodipro Plus in details

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Use: Labeled Indications

Used topically as an antiseptic in the management of minor, superficial skin wounds and has been used to disinfect the skin preoperatively

Jodipro Plus description

Jodipro Plus as oral and topical/cutaneous formulations is prescribed for the treatment of Jodipro Plus deficiency disorders, pre-operative reduction of vascularity of thyroid glands, protection against radioactive Jodipro Plus, cutaneous or lymphocutaneous sporotrichosis, Grave’s disease, cleaning of minor or superficial wounds, thyroid storm and cleaning of wet wounds and ulcers.

Jodipro Plus dosage

Oral

Preoperative reduction of vascularity of the thyroid gland

Adult: As potassium iodide: 50-250 mg (approx 1-5 drops of a solution containing 1 g/ml) tid for 10-14 days before surgery.

Child: As potassium iodide: 50-250 mg (approx 1-5 drops of a solution containing 1 g/ml) tid for 10-14 days before surgery. As strong Jodipro Plus solution: 0.1-0.3 ml (or approx 3-5 drops) tid.

Reconstitution: Administer potassium iodide oral solution in a large quantity (240 ml) of water, or in fruit juice, milk formula or broth.

Oral

Grave's disease

Child: Neonates: 1 drop of strong Jodipro Plus solution every 8 hr.

Oral

Radiation protection against radioactive Jodipro Plus

Adult: As potassium iodide: 100-150 mg 24 hr before procedure and daily for up to 10 days after procedure.

Child: As potassium iodide: Infants from birth to 1 mth with a predicted thyroid exposure of ≥5 centigrays (cGy): 16 mg. >1 mth to 3 yr with a predicted thyroid exposure of ≥5 cGy: 32 mg. >3 yr to 18 yr (except adolescents approaching adult size) with a predicted thyroid exposure of ≥5 cGy: 65 mg. Do not exceed once-daily doses.

Reconstitution: 130-mg Tablet: Place 1 tablet in a small bowl and pulverise using a metal spoon. Add 20 ml of water to the powder and mix until the powder dissolves. Then add 20 ml of the selected drink and mix. Resulting concentration: 6.25 mg potassium iodide per 5 ml. 65-mg Tablet: Place 1 tablet in a small bowl and pulverise. Add 20 ml of water to the powder and mix until the powder dissolves. Then add 20 ml of the selected drink and mix. Resulting concentration: 8.125 mg potassium iodide per 5 ml.

Oral

Cutaneous or lymphocutaneous sporotrichosis

Adult: As potassium iodide solution containing 1 g/mL: Initially, 1 mL tid, should continue for at least 1 mth after disappearance or stabilisation of the lesions.

Child: As potassium iodide: Initially, 250 mg (approx 5 drops of a solution containing 1 g/ml) tid. Max: 1.25-2 g (approx 25-40 drops) tid. Duration: 3-6 mth.

Reconstitution: Administer potassium iodide solution in a large quantity (240 ml) of water, fruit juice, milk formula or broth.

Oral

Jodipro Plus deficiency disorders

Adult: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Jodipro Plus): 400 mg Jodipro Plus once yrly. Pregnant patient: 200 mg Jodipro Plus as a single dose. Moderate to severe: 300-480 mg Jodipro Plus each yr or 100-300 mg Jodipro Plus every 6 mth and for at least 1 yr postpartum.

Child: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Jodipro Plus): Infants up to 1 yr: Single dose of 100 mg Jodipro Plus; 1-5 yr: 200 mg Jodipro Plus; >6 yr: 400 mg Jodipro Plus.

Oral

Thyroid storm

Adult: As potassium iodide: Up to 500 mg every 4 hr.

Intramuscular

Jodipro Plus deficiency disorders

Adult: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Jodipro Plus): Up to 45 yr: 380 mg Jodipro Plus, as single IM doses to provide adequate protection from Jodipro Plus deficiency for up to 3 yr. Pregnant patient: Moderate to severe: 480 mg Jodipro Plus each yr.

Child: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Jodipro Plus): 380 mg Jodipro Plus, as single IM doses to provide adequate protection from Jodipro Plus deficiency for up to 3 yr. Infants up to 1 yr: 190 mg Jodipro Plus, as iodised oil (480 mg/ml Jodipro Plus).

Topical/Cutaneous

Minor, superficial skin wounds

Adult: As 2% or 2.5% solution/ointment: Apply small amount to the affected area 1-3 times daily.

Child: As 2% or 2.5% solution/ointment: Apply small amount to the affected area 1-3 times daily.

Topical/Cutaneous

Cleaning wet ulcers and wounds

Adult: As 0.9% topical gel: Apply to clean wound. Max: 50 g/application and 150 g/wk. Change dressing about 3 times/wk and reduce applications as exudate decreases. Do not use for >3 mth and stop treatment when wound is free of exudate.

Child: As 0.9% topical gel: Apply to clean wound. Max: 50 g/application and 150 g/wk. Change dressing about 3 times/wk and reduce applications as exudate decreases. Do not use for >3 mth and stop treatment when wound is free of exudate.

Jodipro Plus interactions

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What other drugs will affect Jodipro Plus?

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There is a potential risk of interaction with lithium, resulting in an increased possibility of hypothyroidism.

this medicineshould not be used concomitantly with mercurial antiseptics, e.g. mercurochrome and thiomersal.

Since Jodipro Plus may be absorbed systemically, the result of tests of the thyroid function can be influenced.

Jodipro Plus side effects

See also:
What are the possible side effects of Jodipro Plus?

Jodipro Plus and iodides, whether applied topically or given systemically, can give rise to hypersensitivity reactions which may include urticaria, angioedema, cutaneous haemorrhage or purpuras, fever, arthralgia, lymphadenopathy, and eosinophilia.

Inhalation of Jodipro Plus vapour is very irritating to mucous membranes.

Jodipro Plus and iodides have variable effects on the thyroid and can produce goitre and hypothyroidism as well as hyperthyroidism (the Iod-Basedow or Jod-Basedow phenomenon). Goitre and hypothyroidism have also occurred in infants born to mothers who had taken iodides during pregnancy.

Prolonged use may lead to a range of adverse effects, often called ’iodism’, some of which may again be due to hypersensitivity. Adverse effects include metallic taste, increased salivation, burning or painful mouth; there may be acute rhinitis, coryza-like symptoms, and swelling and inflammation of the throat. Eyes may be irritated and swollen and there may be increased lachrymation. Pulmonary oedema, dyspnoea, and bronchitis may develop. Skin reactions include acneform or, more rarely, severe eruptions (iododerma). Other reported effects include depression, insomnia, impotence, headache, and gastrointestinal disturbances, notably nausea, vomiting, and diarrhoea.

Jodipro Plus contraindications

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Allergy to Jodipro Plus,

- Class III patients with Okuda

- Extrahepatic metastases,

- Respiratory or renal insufficiencies severe

- Cons-indications for hepatic arteriography,

- Leukopenia below 1500/mm3 or thrombocytopenia less 50000/mm3,

- Pregnant woman: Jodipro Plus should not be administered to pregnant women. In women of childbearing age, suspicion of pregnancy must be excluded before the administration of Jodipro Plus. Contraception must be instituted and prosecuted in the administration at least a year.

- Breastfeeding: Breastfeeding should be stopped.

Active ingredient matches for Jodipro Plus:

Iodine in Netherlands.


List of Jodipro Plus substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Jolethin 0.75 mg x 1000's
Solution; Topical; Iodine / Nonyl Phenoxypoly Ethoxy Ethanol - Iodine Complex 1.75%
Liquid; Teat-Dip; Iodine / Nonyl Phenoxypoly Ethoxy Ethanol - Iodine Complex 9.6%
Liquid; Disinfectant / Domestic; Iodine / Polyethoxy Polypropoxy Polyethoxy Ethanol - Iodine Complex 25%
Liquid; Disinfectant / Food Premises; Iodine / Polyethoxy Polypropoxy Polyethoxy Ethanol - Iodine Complex 25%
Bath Additive; Liquid; Iodine (Atzinger)
Licoray Plus Lycopene 10% 2000 mcg, vitaminA 2500 IU, vitamin C 50 mg, vitamin E 10 IU, vitamin B1 2mg, vitamin B2 3 mg, vitaminB6 1.5 mg, selenium 35 mcg, zinc gluconate 3 mg, manganesegluconate 100 mcg, iodine 75mcg, copper sulphate 500mcg/10 mL. SYR / 20$ 1.19
Licoray Plus Lycopene 10% 2000 mcg, vitaminA 2500 IU, vitamin C 50 mg, vitamin E 10 IU, vitamin B1 2mg, vitamin B2 3 mg, vitaminB6 1.5 mg, selenium 35 mcg, zinc gluconate 3 mg, manganesegluconate 100 mcg, iodine 75mcg, copper sulphate 500mcg/10 mL SYR / 200$ 1.19
Licoray Plus Lycopene 10% 2000 mcg, vitaminA 2500 IU, vitamin C 50 mg, vitamin E 10 IU, vitamin B1 2mg, vitamin B2 3 mg, vitaminB6 1.5 mg, selenium 35 mcg, zinc gluconate 3 mg, manganesegluconate 100 mcg, iodine 75mcg, copper sulphate 500mcg/10 mL. SYR / 20$ 1.19
Licoray Plus Lycopene 10% 2000 mcg, vitaminA 2500 IU, vitamin C 50 mg, vitamin E 10 IU, vitamin B1 2mg, vitamin B2 3 mg, vitaminB6 1.5 mg, selenium 35 mcg, zinc gluconate 3 mg, manganesegluconate 100 mcg, iodine 75mcg, copper sulphate 500mcg/10 mL SYR / 200$ 1.19
Licoray Plus Lycopene 10% 2000 mcg, vitaminA 2500 IU, vitamin C 50 mg, vitamin E 10 IU, vitamin B1 2mg, vitamin B2 3 mg, vitaminB6 1.5 mg, selenium 35 mcg, zinc gluconate 3 mg, manganesegluconate 100 mcg, iodine 75mcg, copper sulphate 500mcg/10 mL SYR / 200$ 1.19
Licoray Plus Lycopene 10% 2000 mcg, vitaminA 2500 IU, vitamin C 50 mg, vitamin E 10 IU, vitamin B1 2mg, vitamin B2 3 mg, vitaminB6 1.5 mg, selenium 35 mcg, zinc gluconate 3 mg, manganesegluconate 100 mcg, iodine 75mcg, copper sulphate 500mcg/10 mL. SYR / 20$ 1.19
Licoray Plus Lycopene 10% 2000 mcg, vitaminA 2500 IU, vitamin C 50 mg, vitamin E 10 IU, vitamin B1 2mg, vitamin B2 3 mg, vitaminB6 1.5 mg, selenium 35 mcg, zinc gluconate 3 mg, manganesegluconate 100 mcg, iodine 75mcg, copper sulphate 500mcg/10 mL SYR / 200$ 1.19
Licoray Plus Lycopene 10% 2000 mcg, vitaminA 2500 IU, vitamin C 50 mg, vitamin E 10 IU, vitamin B1 2mg, vitamin B2 3 mg, vitaminB6 1.5 mg, selenium 35 mcg, zinc gluconate 3 mg, manganesegluconate 100 mcg, iodine 75mcg, copper sulphate 500mcg/10 mL. SYR / 20$ 1.19
Injectable; Injection; Oeillette Oil Ethyl Esters of Fatty Acid Iodine 2220 MBq (Cis)
Injectable; Injection; Iodine / Ethiodized Oil 380 mg / g
Liquid; Oral; Iodine 0.15 mg / 0.04 ml
Liquid; Oral; Iodine / Potassium Iodide 1 mg / ml
Liquid; Topical; Iodine / Nonyl Phenoxypoly Ethoxy Ethanol - Iodine Complex 1%
Liquid; Udder Wash; Iodine / Nonyl Phenoxypoly Ethoxy Ethanol - Iodine Complex 1.75% (Waves-Biotech)
Lp-30 30mg CAP / 10 (Waves-Biotech)$ 0.58
30 mg x 10's (Waves-Biotech)$ 0.58

References

  1. PubChem. "Iodine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Iodine". http://www.drugbank.ca/drugs/DB05382 (accessed September 17, 2018).
  3. DTP/NCI. "iodine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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