Pyrantel Pamoate Farnam Uses

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What is Pyrantel Pamoate Farnam?

Pyrantel Pamoate Farnam belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.

Pyrantel Pamoate Farnam is used to treat pinworms (enterobiasis; oxyuriasis).

Pyrantel Pamoate Farnam may also be used for other worm infections as determined by your doctor.

Pyrantel Pamoate Farnam works by paralyzing the worms. They are then passed in the stool.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Pyrantel Pamoate Farnam is used in certain patients with the following medical condition:

For patients taking Pyrantel Pamoate Farnam for hookworm infection :

Pyrantel Pamoate Farnam indications

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Oral

Single or mixed infections due to susceptible worms

Adult: 10 mg/kg as a single dose.

Child: 10 mg/kg as a single dose.

Oral

Ascariasis

Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr.

Oral

Necatoriasis

Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days.

Oral

Enterobiasis

Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose.

Oral

Trichinosis

Adult: 10 mg/kg daily for 5 days.

How should I use Pyrantel Pamoate Farnam?

Use Pyrantel Pamoate Farnam as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Pyrantel Pamoate Farnam.

Pyrantel Pamoate Farnam description

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Pyrantel Pamoate Farnam is an antinematodal thiophene

Pyrantel Pamoate Farnam dosage

Pyrantel Pamoate Farnam Dosage

Applies to the following strength(s): 144 mg/mL; 180 mg; 50 mg/mL

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Enterobiasis

11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.

Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)

11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.

Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)

11 mg/kg base (maximum 1 g) orally daily for 3 days.

Usual Adult Dose for Ascariasis

11 mg/kg base (maximum 1 g) orally once.

Usual Adult Dose for Trichostrongylosis

11 mg/kg base (maximum 1 g) orally once.

Usual Adult Dose for Moniliformis Infection

11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.

Usual Pediatric Dose for Enterobiasis

>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.

Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)

>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.

Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)

>=2 years: 11 mg/kg base (maximum 1 g) orally daily for 3 days.

Usual Pediatric Dose for Ascariasis

>=2 years: 11 mg/kg base (maximum 1 g) orally once.

Usual Pediatric Dose for Trichostrongylosis

>=2 years: 11 mg/kg base (maximum 1 g) orally once.

Usual Pediatric Dose for Moniliformis Infection

>=2 years: 11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Pyrantel Pamoate Farnam is contraindicated in patients with hepatic disease.

Dose Adjustments

In the treatment of ascariasis, Pyrantel Pamoate Farnam may be used only if it has been determined that the worm load will not worsen obstruction.

Precautions

Pyrantel Pamoate Farnam is contraindicated in patients with hepatic disease.

When one individual in a household has pinworms, the entire household should be treated unless otherwise advised. Pinworm infections are easily transmitted to others in the same household.

Pyrantel Pamoate Farnam should be used with caution in patients with severe malnutrition or anemia. Supportive therapy is recommended for anemic, dehydrated, or malnourished patients prior to administration of the drug.

Other medications are known to antagonize the anthelmintic effect of Pyrantel Pamoate Farnam. Patients should be advised to consult with their physician before initiating any drug therapy while receiving Pyrantel Pamoate Farnam.

Dialysis

Data not available

Other Comments

The dose should be taken as a single oral dose. It may be taken alone or with milk or fruit juice.

Pyrantel Pamoate Farnam pamoate 2.9 g is approximately equivalent to 1 g of Pyrantel Pamoate Farnam (base).

More about Pyrantel Pamoate Farnam

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Pyrantel Pamoate Farnam interactions

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What other drugs will affect Pyrantel Pamoate Farnam?

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• Dexamethasone

Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.

• Praziquantel

• Cimetidine

Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12). Albendazole sulfoxide plasma concentrations were unchanged 4 hours after dosing.

• Theophylline

The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of albendazole (400 mg) in 6 healthy subjects.

Pyrantel Pamoate Farnam side effects

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What are the possible side effects of Pyrantel Pamoate Farnam?

Applies to Pyrantel Pamoate Farnam: oral suspension, oral tablet, oral tablet chewable

In addition to its needed effects, some unwanted effects may be caused by Pyrantel Pamoate Farnam (the active ingredient contained in Pyrantel Pamoate Farnam). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Pyrantel Pamoate Farnam, check with your doctor or nurse as soon as possible:

Rare

Minor Side Effects

Some of the side effects that can occur with Pyrantel Pamoate Farnam may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

Pyrantel Pamoate Farnam contraindications

See also:
What is the most important information I should know about Pyrantel Pamoate Farnam?

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This medicine is contraindicated in patients with known hypersensitivity to the benzimidazole class of compounds or any components of this medicine.

Active ingredient matches for Pyrantel Pamoate Farnam:

Pyrantel in United States.


List of Pyrantel Pamoate Farnam substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Pyrantelum Medana / / höông vò mô 250 mg/5 mL x 1 Bottle 15 mL in duïng cuï ñong coù chia vaïch
Pyrapam 125 mg x 1, 000's (General Drugs House)
Pyrapam 50 mg/1 mL x 10 mL (General Drugs House)
Pyrapam oral susp 50 mg/mL 10 mL x 1's (General Drugs House)
Pyrapam tab 125 mg 1000's (General Drugs House)
Pyteldon 125 mg x 100's
Pyteldon 250 mg/5 mL x 10 mL x 12's
Quantrel 10 mL (Johnson & Johnson)$ 3.57
Quantrel oral susp 10 mL x 1's (Johnson & Johnson)$ 3.57
Drug Premix; Oral; Pyrantel Tartrate 10.6 g / kg
Paste; Oral; Pyrantel Pamoate 3.58 g
Suspension; Oral; Pyrantel Pamoate 50 mg / ml
Thelmex 250mg TAB / 3 (BPL Pharmaceuticals (P) Ltd.)$ 0.14

References

  1. PubChem. "PYRANTEL". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Pyrantel". http://www.drugbank.ca/drugs/DB11156 (accessed September 17, 2018).
  3. MeSH. "Antinematodal Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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