Delarex Uses

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What is Delarex?

Delarex is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Delarex is used to treat the symptoms of allergies, such as sneezing, watery eyes, and runny nose. It is also used to treat skin hives and itching in people with chronic skin reactions.

Delarex may also be used for purposes not listed in this medication guide.

Delarex indications

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1.1 Seasonal Allergic Rhinitis

Delarex Tablets are indicated for the relief of the nasal and non-nasal symptoms of seasonal allergic rhinitis in patients 12 years of age and older.

1.2 Perennial Allergic Rhinitis

Delarex Tablets are indicated for the relief of the nasal and non-nasal symptoms of perennial allergic rhinitis in patients 12 years of age and older.

1.3 Chronic Idiopathic Urticaria

Delarex Tablets are indicated for the symptomatic relief of pruritus, reduction in the number of hives, and size of hives, in patients with chronic idiopathic urticaria 12 years of age and older.

How should I use Delarex?

Use Delarex orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Delarex orally disintegrating tablets.

Uses of Delarex in details

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Use: Labeled Indications

Allergic rhinitis: Relief of nasal and non-nasal symptoms of seasonal (SAR) and perennial (PAR) allergic rhinitis

Urticaria: Symptomatic relief of pruritus, reduction in number of hives, and reduction in size of hives associated with chronic idiopathic urticaria (CIU)

Off Label Uses

NSAID-associated urticaria (prophylaxis)

Data from a retrospective study with a limited number of patients suggest that Delarex may be beneficial for prophylactic therapy in patients with NSAID-associated urticaria prior to receiving a strong COX-1 inhibitor. Additional trials may be needed to further define the role of Delarex in this setting.

Delarex description

Delarex Tab: Each tablet contains 5.0 mg of Delarex.

Delarex Syr: Each mL of Delarex syrup contains 500 mcg of Delarex.

Excipients/Inactive Ingredients: Delarex Tab: Dibasic calcium phosphate dihydrate, microcrystalline cellulose, maize starch, talc, blue color film-coat material, clear film coat material, white wax and carnauba wax.

Delarex dosage

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Delarex Dosage

Generic name: Delarex 5mg

Dosage form: tablet, film coated; oral solution

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Although an orally disintegrating tablet formulation of Delarex may be available in the marketplace, Delarex® RediTabs® Tablets are no longer marketed.

Delarex Tablets,

Oral Solution, or RediTabs Tablets may be taken without regard to meals. Place Delarex (Delarex) RediTabs Tablets on the tongue and allow to disintegrate before swallowing. Tablet disintegration occurs rapidly. Administer with or without water. Take tablet immediately after opening the blister.

The age-appropriate dose of Delarex

Oral Solution should be administered with a commercially available measuring dropper or syringe that is calibrated to deliver 2 mL and 2.5 mL (½ teaspoon).

Adults and Adolescents 12 Years of Age and Over

The recommended dose of Delarex Tablets or Delarex Tablets is one 5-mg tablet once daily. The recommended dose of Delarex

Oral Solution is 2 teaspoonfuls (5 mg in 10 mL) once daily.

Children 6 to 11 Years of Age

The recommended dose of Delarex

Oral Solution is 1 teaspoonful (2.5 mg in 5 mL) once daily. The recommended dose of Delarex Tablets is one 2.5-mg tablet once daily.

Children 12 Months to 5 Years of Age

The recommended dose of Delarex

Oral Solution is ½ teaspoonful (1.25 mg in 2.5 mL) once daily.

Children 6 to 11 Months of Age

The recommended dose of Delarex

Oral Solution is 2 mL (1 mg) once daily.

Adults with Hepatic or Renal Impairment

In adult patients with liver or renal impairment, a starting dose of one 5-mg tablet every other day is recommended based on pharmacokinetic data. Dosing recommendation for children with liver or renal impairment cannot be made due to lack of data.

More about Delarex (Delarex)

Consumer resources

Professional resources

Other formulations

Related treatment guides

Delarex interactions

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What other drugs will affect Delarex?

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Inhibitors Of Cytochrome P450 3A4

In controlled clinical studies co-administration of Delarex with ketoconazole, erythromycin, or azithromycin resulted in increased plasma concentrations of Delarex and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Delarex.

Fluoxetine

In controlled clinical studies co-administration of Delarex with fluoxetine, a selective serotonin reuptake inhibitor (SSRI), resulted in increased plasma concentrations of Delarex and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Delarex.

Cimetidine

In controlled clinical studies co-administration of Delarex with cimetidine, a histamine H2-receptor antagonist, resulted in increased plasma concentrations of Delarex and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Delarex.

Drug Abuse And Dependence

There is no information to indicate that abuse or dependency occurs with Delarex Tablets.

Delarex side effects

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What are the possible side effects of Delarex?

In clinical trials in a range of indications including allergic rhinitis and chronic idiopathic urticaria, at the recommended dose of 5 mg daily, undesirable effects with Delarex tablets were reported in 3 % of patients in excess of those treated with placebo. The most frequent adverse events reported in excess of placebo were fatigue (1.2 %), dry mouth (0.8 %), and headache (0.6 %).

Very rare cases of hypersensitivity reactions (including anaphylaxis and rash) tachycardia, palpitations, psychomotor hyperactivity, seizures, elevations of liver enzymes, hepatitis, and increased bilirubin have been reported during the marketing of Delarex.

Delarex Syr: In clinical trials in a paediatric population, Delarex Syrup was administered to a total of 246 children aged 6 months through 11 years. The overall incidence of adverse events in children 2 through 11 years of age was similar for Delarex Syrup and the placebo groups. In infants and toddlers aged 6 to 23 months, the most frequent adverse events reported in excess of placebo were diarrhea (3.7%), fever (2.3%) and insomnia (2.3%).

Delarex contraindications

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What is the most important information I should know about Delarex?

You should not take this medication if you are allergic to Delarex or to loratadine (Claritin).

Before taking Delarex, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.

Do not give this medication to a child younger than 2 years old without the advice of a doctor.

Delarex disintegrating tablets (Delarex) may contain phenylalanine. Talk to your doctor before using this form of Delarex if you have phenylketonuria (PKU).

Active ingredient matches for Delarex:

Desloratadine in Egypt.


List of Delarex substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Dekast 10+5 Tablet (Grownbury Pharmaceuticals Pvt.Ltd)$ 0.16
Deline 100 mg Capsule (Alde Medi Impex Ltd.)$ 0.02
DELINE 100MG CAPSULE 1 strip / 10 capsules each (Alde Medi Impex Ltd.)$ 0.21
DELINE cap 10's (Alde Medi Impex Ltd.)
Deline 100mg Capsule (Alde Medi Impex Ltd.)$ 0.02
Delopa 5 mg x 10 Blister x 10 Tablet
Delopedil 5 mg x 1 Blister 10 Tablet
DELORID TABLET 1 strip / 10 tablets each (Zyris Derma Care (P) Ltd)$ 0.41
DELORTA Capsule/ Tablet / 5mg / 10 units (Abbott Healthcare Pvt Ltd (AHPL))$ 0.52
5 mg x 10's (Abbott Healthcare Pvt Ltd (AHPL))$ 0.48
Delorta 5mg TAB / 10 (Abbott Healthcare Pvt Ltd (AHPL))$ 0.48
Delorta 5 mg Tablet (Abbott Healthcare Pvt Ltd (AHPL))$ 0.05
DELORTA tab 5 mg x 10's (Abbott Healthcare Pvt Ltd (AHPL))$ 0.48
Delorta 5mg TAB / 10 (Abbott Healthcare Pvt Ltd (AHPL))$ 0.48
Delotid 5mg TAB / 10 (DWD)
5 mg x 10's (DWD)
DELOTID tab 5 mg x 10's (DWD)$ 0.50
Denosin 5 mg x 50 x 10's
Denosin 20 mg x 10 Blister x 10 Tablet
DES - OD Capsule/ Tablet / 5mg / 10 units (Cadila Pharmaceuticals (Le Sante Division))$ 0.50
Des OD 5 mg x 10 Blister x 10 Tablet (Le Sante (Cadila Pharmaceuticals Ltd.))
Des OD 5 mg Tablet (Le Sante (Cadila Pharmaceuticals Ltd.))$ 0.05
DES OD 10 MG TABLET 1 strip / 10 tablets each (Le Sante (Cadila Pharmaceuticals Ltd.))$ 0.60
Des OD 10mg Tablet (Le Sante (Cadila Pharmaceuticals Ltd.))$ 0.07
Des-OD 5mg FC-TAB / 10 (Cadila (Le Sante))$ 0.43

References

  1. DailyMed. "DESLORATADINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "Desloratadine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "Desloratadine". http://www.drugbank.ca/drugs/DB00967 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Delarex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Delarex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Delarex drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Not expensive1
100.0%


1 consumer reported time for results

To what extent do I have to use Delarex before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Delarex. To get the time effectiveness of using Delarex drug by other patients, please click here.
Users%
1 day1
100.0%


4 consumers reported age

Users%
16-291
25.0%
> 601
25.0%
30-451
25.0%
46-601
25.0%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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