Deslodyna Pro Uses

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What is Deslodyna Pro?

Deslodyna Pro is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Deslodyna Pro is used to treat the symptoms of allergies, such as sneezing, watery eyes, and runny nose. It is also used to treat skin hives and itching in people with chronic skin reactions.

Deslodyna Pro may also be used for purposes not listed in this medication guide.

Deslodyna Pro indications

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1.1 Seasonal Allergic Rhinitis

Deslodyna Pro Tablets are indicated for the relief of the nasal and non-nasal symptoms of seasonal allergic rhinitis in patients 12 years of age and older.

1.2 Perennial Allergic Rhinitis

Deslodyna Pro Tablets are indicated for the relief of the nasal and non-nasal symptoms of perennial allergic rhinitis in patients 12 years of age and older.

1.3 Chronic Idiopathic Urticaria

Deslodyna Pro Tablets are indicated for the symptomatic relief of pruritus, reduction in the number of hives, and size of hives, in patients with chronic idiopathic urticaria 12 years of age and older.

How should I use Deslodyna Pro?

Use Deslodyna Pro orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Deslodyna Pro orally disintegrating tablets.

Uses of Deslodyna Pro in details

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Use: Labeled Indications

Allergic rhinitis: Relief of nasal and non-nasal symptoms of seasonal (SAR) and perennial (PAR) allergic rhinitis

Urticaria: Symptomatic relief of pruritus, reduction in number of hives, and reduction in size of hives associated with chronic idiopathic urticaria (CIU)

Off Label Uses

NSAID-associated urticaria (prophylaxis)

Data from a retrospective study with a limited number of patients suggest that Deslodyna Pro may be beneficial for prophylactic therapy in patients with NSAID-associated urticaria prior to receiving a strong COX-1 inhibitor. Additional trials may be needed to further define the role of Deslodyna Pro in this setting.

Deslodyna Pro description

Deslodyna Pro Tab: Each tablet contains 5.0 mg of Deslodyna Pro.

Deslodyna Pro Syr: Each mL of Deslodyna Pro syrup contains 500 mcg of Deslodyna Pro.

Excipients/Inactive Ingredients: Deslodyna Pro Tab: Dibasic calcium phosphate dihydrate, microcrystalline cellulose, maize starch, talc, blue color film-coat material, clear film coat material, white wax and carnauba wax.

Deslodyna Pro dosage

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Deslodyna Pro Dosage

Generic name: Deslodyna Pro 5mg

Dosage form: tablet, film coated; oral solution

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Although an orally disintegrating tablet formulation of Deslodyna Pro may be available in the marketplace, Deslodyna Pro® RediTabs® Tablets are no longer marketed.

Deslodyna Pro Tablets,

Oral Solution, or RediTabs Tablets may be taken without regard to meals. Place Deslodyna Pro (Deslodyna Pro) RediTabs Tablets on the tongue and allow to disintegrate before swallowing. Tablet disintegration occurs rapidly. Administer with or without water. Take tablet immediately after opening the blister.

The age-appropriate dose of Deslodyna Pro

Oral Solution should be administered with a commercially available measuring dropper or syringe that is calibrated to deliver 2 mL and 2.5 mL (½ teaspoon).

Adults and Adolescents 12 Years of Age and Over

The recommended dose of Deslodyna Pro Tablets or Deslodyna Pro Tablets is one 5-mg tablet once daily. The recommended dose of Deslodyna Pro

Oral Solution is 2 teaspoonfuls (5 mg in 10 mL) once daily.

Children 6 to 11 Years of Age

The recommended dose of Deslodyna Pro

Oral Solution is 1 teaspoonful (2.5 mg in 5 mL) once daily. The recommended dose of Deslodyna Pro Tablets is one 2.5-mg tablet once daily.

Children 12 Months to 5 Years of Age

The recommended dose of Deslodyna Pro

Oral Solution is ½ teaspoonful (1.25 mg in 2.5 mL) once daily.

Children 6 to 11 Months of Age

The recommended dose of Deslodyna Pro

Oral Solution is 2 mL (1 mg) once daily.

Adults with Hepatic or Renal Impairment

In adult patients with liver or renal impairment, a starting dose of one 5-mg tablet every other day is recommended based on pharmacokinetic data. Dosing recommendation for children with liver or renal impairment cannot be made due to lack of data.

More about Deslodyna Pro (Deslodyna Pro)

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Deslodyna Pro interactions

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What other drugs will affect Deslodyna Pro?

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Inhibitors Of Cytochrome P450 3A4

In controlled clinical studies co-administration of Deslodyna Pro with ketoconazole, erythromycin, or azithromycin resulted in increased plasma concentrations of Deslodyna Pro and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Deslodyna Pro.

Fluoxetine

In controlled clinical studies co-administration of Deslodyna Pro with fluoxetine, a selective serotonin reuptake inhibitor (SSRI), resulted in increased plasma concentrations of Deslodyna Pro and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Deslodyna Pro.

Cimetidine

In controlled clinical studies co-administration of Deslodyna Pro with cimetidine, a histamine H2-receptor antagonist, resulted in increased plasma concentrations of Deslodyna Pro and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Deslodyna Pro.

Drug Abuse And Dependence

There is no information to indicate that abuse or dependency occurs with Deslodyna Pro Tablets.

Deslodyna Pro side effects

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What are the possible side effects of Deslodyna Pro?

In clinical trials in a range of indications including allergic rhinitis and chronic idiopathic urticaria, at the recommended dose of 5 mg daily, undesirable effects with Deslodyna Pro tablets were reported in 3 % of patients in excess of those treated with placebo. The most frequent adverse events reported in excess of placebo were fatigue (1.2 %), dry mouth (0.8 %), and headache (0.6 %).

Very rare cases of hypersensitivity reactions (including anaphylaxis and rash) tachycardia, palpitations, psychomotor hyperactivity, seizures, elevations of liver enzymes, hepatitis, and increased bilirubin have been reported during the marketing of Deslodyna Pro.

Deslodyna Pro Syr: In clinical trials in a paediatric population, Deslodyna Pro Syrup was administered to a total of 246 children aged 6 months through 11 years. The overall incidence of adverse events in children 2 through 11 years of age was similar for Deslodyna Pro Syrup and the placebo groups. In infants and toddlers aged 6 to 23 months, the most frequent adverse events reported in excess of placebo were diarrhea (3.7%), fever (2.3%) and insomnia (2.3%).

Deslodyna Pro contraindications

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What is the most important information I should know about Deslodyna Pro?

You should not take this medication if you are allergic to Deslodyna Pro or to loratadine (Claritin).

Before taking Deslodyna Pro, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.

Do not give this medication to a child younger than 2 years old without the advice of a doctor.

Deslodyna Pro disintegrating tablets (Deslodyna Pro) may contain phenylalanine. Talk to your doctor before using this form of Deslodyna Pro if you have phenylketonuria (PKU).

Active ingredient matches for Deslodyna Pro:

Desloratadine in Poland.


List of Deslodyna Pro substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Deslogen FC tab 5 mg 100's (InnoGen Pharmaceuticals)
Deslogen syr 2.5 mg/5 mL / / bubblegum flavor 60 mL x 1's (InnoGen Pharmaceuticals)
Desloget 5 mg x 1 Blister x 10 Tablet
DESLOR Capsule/ Tablet / 5mg / 10 units (Solarase (Sun Pharmaceutical Industries Ltd.))$ 0.61
Deslor 5mg TAB / 10 (Solarase (Sun Pharmaceutical Industries Ltd.))$ 0.66
5 mg x 10's (Solarase (Sun Pharmaceutical Industries Ltd.))$ 0.66
Deslor 5 mg x 100's (Solarase (Sun Pharmaceutical Industries Ltd.))
Deslor 5 mg Tablet (Solarase (Sun Pharmaceutical Industries Ltd.))$ 0.07
DESLOR 5 MG TABLET 1 strip / 10 tablets each (Solarase (Sun Pharmaceutical Industries Ltd.))$ 0.88
DESLOR 5 MG TABLET MD 1 strip / 10 tablet mds each (Solarase (Sun Pharmaceutical Industries Ltd.))$ 0.73
DESLOR tab 5 mg x 10's (Solarase (Sun Pharmaceutical Industries Ltd.))$ 0.71
Deslor 5mg Tablet (Solarase (Sun Pharmaceutical Industries Ltd.))$ 0.09
Deslor 5mg Tablet MD (Solarase (Sun Pharmaceutical Industries Ltd.))$ 0.07
Deslora 5 mg x 3 Blister x 10 Tablet (Stada)
Deslora FC tab 5 mg 5's (Stada)
DESLORANID tab 5 mg x 10's (Nidus)$ 0.45

References

  1. DailyMed. "DESLORATADINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "Desloratadine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "Desloratadine". http://www.drugbank.ca/drugs/DB00967 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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