What is Destadin?
Destadin is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Destadin is used to treat the symptoms of allergies, such as sneezing, watery eyes, and runny nose. It is also used to treat skin hives and itching in people with chronic skin reactions.
Destadin may also be used for purposes not listed in this medication guide.
Destadin indications
1.1 Seasonal Allergic Rhinitis
Destadin Tablets are indicated for the relief of the nasal and non-nasal symptoms of seasonal allergic rhinitis in patients 12 years of age and older.
1.2 Perennial Allergic Rhinitis
Destadin Tablets are indicated for the relief of the nasal and non-nasal symptoms of perennial allergic rhinitis in patients 12 years of age and older.
1.3 Chronic Idiopathic Urticaria
Destadin Tablets are indicated for the symptomatic relief of pruritus, reduction in the number of hives, and size of hives, in patients with chronic idiopathic urticaria 12 years of age and older.
How should I use Destadin?
Use Destadin orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Destadin orally disintegrating tablets. Talk to your pharmacist if you have questions about this information.
- Take Destadin orally disintegrating tablets by mouth with or without food.
- Do not remove the blister from the outer pouch until you are ready to take Destadin orally disintegrating tablets. Make sure that your hands are dry when you open the blister pack. Do not push the tablet through the foil. Peel back the foil on the blister pack and place the tablet on your tongue. The tablet dissolves quickly and can be swallowed with saliva. Destadin orally disintegrating tablets may be taken with or without water. Take the tablet immediately after opening the blister pack. Do not store the removed tablet for future use.
- If you miss a dose of Destadin orally disintegrating tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Destadin orally disintegrating tablets.
Uses of Destadin in details
Use: Labeled Indications
Allergic rhinitis: Relief of nasal and non-nasal symptoms of seasonal (SAR) and perennial (PAR) allergic rhinitis
Urticaria: Symptomatic relief of pruritus, reduction in number of hives, and reduction in size of hives associated with chronic idiopathic urticaria (CIU)
Off Label Uses
NSAID-associated urticaria (prophylaxis)
Data from a retrospective study with a limited number of patients suggest that Destadin may be beneficial for prophylactic therapy in patients with NSAID-associated urticaria prior to receiving a strong COX-1 inhibitor. Additional trials may be needed to further define the role of Destadin in this setting.
Destadin description
Destadin Tab: Each tablet contains 5.0 mg of Destadin.
Destadin Syr: Each mL of Destadin syrup contains 500 mcg of Destadin.
Excipients/Inactive Ingredients: Destadin Tab: Dibasic calcium phosphate dihydrate, microcrystalline cellulose, maize starch, talc, blue color film-coat material, clear film coat material, white wax and carnauba wax.
Destadin dosage
Destadin Dosage
Generic name: Destadin 5mg
Dosage form: tablet, film coated; oral solution
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Although an orally disintegrating tablet formulation of Destadin may be available in the marketplace, Destadin® RediTabs® Tablets are no longer marketed.
Destadin Tablets,
Oral Solution, or RediTabs Tablets may be taken without regard to meals. Place Destadin (Destadin) RediTabs Tablets on the tongue and allow to disintegrate before swallowing. Tablet disintegration occurs rapidly. Administer with or without water. Take tablet immediately after opening the blister.
The age-appropriate dose of Destadin
Oral Solution should be administered with a commercially available measuring dropper or syringe that is calibrated to deliver 2 mL and 2.5 mL (½ teaspoon).
Adults and Adolescents 12 Years of Age and Over
The recommended dose of Destadin Tablets or Destadin Tablets is one 5-mg tablet once daily. The recommended dose of Destadin
Oral Solution is 2 teaspoonfuls (5 mg in 10 mL) once daily.
Children 6 to 11 Years of Age
The recommended dose of Destadin
Oral Solution is 1 teaspoonful (2.5 mg in 5 mL) once daily. The recommended dose of Destadin Tablets is one 2.5-mg tablet once daily.
Children 12 Months to 5 Years of Age
The recommended dose of Destadin
Oral Solution is ½ teaspoonful (1.25 mg in 2.5 mL) once daily.
Children 6 to 11 Months of Age
The recommended dose of Destadin
Oral Solution is 2 mL (1 mg) once daily.
Adults with Hepatic or Renal Impairment
In adult patients with liver or renal impairment, a starting dose of one 5-mg tablet every other day is recommended based on pharmacokinetic data. Dosing recommendation for children with liver or renal impairment cannot be made due to lack of data.
More about Destadin (Destadin)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 5 Reviews - Add your own review/rating
- Generic Availability
Consumer resources
- Destadin
- Destadin syrup
- Destadin (Advanced Reading)
Professional resources
- Destadin (AHFS Monograph)
- Destadin (FDA)
Other formulations
- Destadin-D 24 Hour
- Destadin-D 12 Hour
- Destadin
Related treatment guides
- Allergic Rhinitis
- Urticaria
Destadin interactions
See also:
What other drugs will affect Destadin?
Inhibitors Of Cytochrome P450 3A4
In controlled clinical studies co-administration of Destadin with ketoconazole, erythromycin, or azithromycin resulted in increased plasma concentrations of Destadin and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Destadin.
Fluoxetine
In controlled clinical studies co-administration of Destadin with fluoxetine, a selective serotonin reuptake inhibitor (SSRI), resulted in increased plasma concentrations of Destadin and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Destadin.
Cimetidine
In controlled clinical studies co-administration of Destadin with cimetidine, a histamine H2-receptor antagonist, resulted in increased plasma concentrations of Destadin and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Destadin.
Drug Abuse And Dependence
There is no information to indicate that abuse or dependency occurs with Destadin Tablets.
Destadin side effects
See also:
What are the possible side effects of Destadin?
In clinical trials in a range of indications including allergic rhinitis and chronic idiopathic urticaria, at the recommended dose of 5 mg daily, undesirable effects with Destadin tablets were reported in 3 % of patients in excess of those treated with placebo. The most frequent adverse events reported in excess of placebo were fatigue (1.2 %), dry mouth (0.8 %), and headache (0.6 %).
Very rare cases of hypersensitivity reactions (including anaphylaxis and rash) tachycardia, palpitations, psychomotor hyperactivity, seizures, elevations of liver enzymes, hepatitis, and increased bilirubin have been reported during the marketing of Destadin.
Destadin Syr: In clinical trials in a paediatric population, Destadin Syrup was administered to a total of 246 children aged 6 months through 11 years. The overall incidence of adverse events in children 2 through 11 years of age was similar for Destadin Syrup and the placebo groups. In infants and toddlers aged 6 to 23 months, the most frequent adverse events reported in excess of placebo were diarrhea (3.7%), fever (2.3%) and insomnia (2.3%).
Destadin contraindications
See also:
What is the most important information I should know about Destadin?
You should not take this medication if you are allergic to Destadin or to loratadine (Claritin).
Before taking Destadin, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.
Do not give this medication to a child younger than 2 years old without the advice of a doctor.
Destadin disintegrating tablets (Destadin) may contain phenylalanine. Talk to your doctor before using this form of Destadin if you have phenylketonuria (PKU).
Active ingredient matches for Destadin:
Desloratadine in Brazil.
List of Destadin substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Destacin (Bangladesh) | |
| Destazine (Pakistan) | |
| Destin (Bangladesh) | |
| Destina (Pakistan) | |
| Desybel 2.5mg/5ml (Bulgaria) | |
| Desybel 5mg (Bulgaria) | |
| Dexio (Colombia, Dominican Republic, Guatemala, Honduras) | |
| Dexio 5 (Colombia) | |
| Dexlor | |
| Dexlor 5mg Tablet MD (La Med India) | $ 0.07 |
| DEXLOR-MD | |
| DEXLY (India) | |
| DEXLY Capsule/ Tablet / 5mg / 10 units (Hetero Healthcare Ltd.) | $ 0.24 |
| Dexly 5mg TAB / 10 (Hetero Healthcare Ltd.) | $ 0.24 |
| 5 mg x 10's (Hetero Healthcare Ltd.) | $ 0.24 |
| Dexly 5 mg Tablet (Hetero Healthcare Ltd.) | $ 0.02 |
| DEXLY 5MG TABLET 1 strip / 10 tablets each (Hetero Healthcare Ltd.) | $ 0.33 |
| DEXLY tab 5 mg x 10's (Hetero Healthcare Ltd.) | $ 0.24 |
| Dexly 5mg TAB / 10 (Hetero Healthcare Ltd.) | $ 0.24 |
| Dexly 5mg Tablet (Hetero Healthcare Ltd.) | $ 0.03 |
| DEZLORID | |
| DEZLORID 10 MG TABLET 1 strip / 10 tablets each (Intas Pharmaceuticals Ltd) | $ 0.64 |
| DEZLORID 5 MG TABLET 1 strip / 10 tablets each (Intas Pharmaceuticals Ltd) | $ 0.70 |
| Dezlorid 10mg Tablet (Intas Pharmaceuticals Ltd) | $ 0.06 |
| Dezlorid 5mg Tablet (Intas Pharmaceuticals Ltd) | $ 0.07 |
| Dictrin (Pakistan) | |
| Dihengsai (China) | |
| Dilora (India) | |
| Dilora 5mg TAB / 10 (Invision Medi Sciences) | $ 0.42 |
| 5 mg x 10's (Invision Medi Sciences) | $ 0.42 |
| Dilora 5 mg Tablet (Invision Medi Sciences) | $ 0.04 |
| Dilora 50+500 Tablet (Invision Medi Sciences) | $ 0.02 |
| DILORA tab 5 mg x 10's (Invision Medi Sciences) | $ 0.48 |
| DISITCH | |
| Dislen (Uruguay) | |
| DISLOR (India) | |
| DISLOR tab 5 mg x 10's (Daksh) | $ 0.47 |
| Dometin (Vietnam) | |
| Dometin 5 mg x 1 Blister x 10 Tablet (Nycomed) | |
| Dometin 5 mg x 3 Blister x 10 Tablet (Nycomed) | |
| Dora (Bangladesh) | |
| Doxafin (Turkey) | |
| Doxtadin (Bosnia & Herzegowina) | |
| Dozanavir (Vietnam) | |
| Dozanavir 5 mg x 3 Blister x 10 Tablet | |
| Dozanavir 5 mg x 6 Blister x 10 Tablet | |
| Dozanavir 5 mg x 10 Blister x 10 Tablet | |
| Dozanavir 5 mg x 1 Bottle 100 Tablet | |
| Dozanavir 5 mg x 1 Bottle 250 Tablet | |
See 812 substitutes for Destadin | |
References
- DailyMed. "DESLORATADINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "Desloratadine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Desloratadine". http://www.drugbank.ca/drugs/DB00967 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Destadin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Destadin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yetConsumer reported age
No survey data has been collected yetConsumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
