What is Despej?
Despej is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Despej is used to treat the symptoms of allergies, such as sneezing, watery eyes, and runny nose. It is also used to treat skin hives and itching in people with chronic skin reactions.
Despej may also be used for purposes not listed in this medication guide.
Despej indications
1.1 Seasonal Allergic Rhinitis
Despej Tablets are indicated for the relief of the nasal and non-nasal symptoms of seasonal allergic rhinitis in patients 12 years of age and older.
1.2 Perennial Allergic Rhinitis
Despej Tablets are indicated for the relief of the nasal and non-nasal symptoms of perennial allergic rhinitis in patients 12 years of age and older.
1.3 Chronic Idiopathic Urticaria
Despej Tablets are indicated for the symptomatic relief of pruritus, reduction in the number of hives, and size of hives, in patients with chronic idiopathic urticaria 12 years of age and older.
How should I use Despej?
Use Despej orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Despej orally disintegrating tablets. Talk to your pharmacist if you have questions about this information.
- Take Despej orally disintegrating tablets by mouth with or without food.
- Do not remove the blister from the outer pouch until you are ready to take Despej orally disintegrating tablets. Make sure that your hands are dry when you open the blister pack. Do not push the tablet through the foil. Peel back the foil on the blister pack and place the tablet on your tongue. The tablet dissolves quickly and can be swallowed with saliva. Despej orally disintegrating tablets may be taken with or without water. Take the tablet immediately after opening the blister pack. Do not store the removed tablet for future use.
- If you miss a dose of Despej orally disintegrating tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Despej orally disintegrating tablets.
Uses of Despej in details
Use: Labeled Indications
Allergic rhinitis: Relief of nasal and non-nasal symptoms of seasonal (SAR) and perennial (PAR) allergic rhinitis
Urticaria: Symptomatic relief of pruritus, reduction in number of hives, and reduction in size of hives associated with chronic idiopathic urticaria (CIU)
Off Label Uses
NSAID-associated urticaria (prophylaxis)
Data from a retrospective study with a limited number of patients suggest that Despej may be beneficial for prophylactic therapy in patients with NSAID-associated urticaria prior to receiving a strong COX-1 inhibitor. Additional trials may be needed to further define the role of Despej in this setting.
Despej description
Despej Tab: Each tablet contains 5.0 mg of Despej.
Despej Syr: Each mL of Despej syrup contains 500 mcg of Despej.
Excipients/Inactive Ingredients: Despej Tab: Dibasic calcium phosphate dihydrate, microcrystalline cellulose, maize starch, talc, blue color film-coat material, clear film coat material, white wax and carnauba wax.
Despej dosage
Despej Dosage
Generic name: Despej 5mg
Dosage form: tablet, film coated; oral solution
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Although an orally disintegrating tablet formulation of Despej may be available in the marketplace, Despej® RediTabs® Tablets are no longer marketed.
Despej Tablets,
Oral Solution, or RediTabs Tablets may be taken without regard to meals. Place Despej (Despej) RediTabs Tablets on the tongue and allow to disintegrate before swallowing. Tablet disintegration occurs rapidly. Administer with or without water. Take tablet immediately after opening the blister.
The age-appropriate dose of Despej
Oral Solution should be administered with a commercially available measuring dropper or syringe that is calibrated to deliver 2 mL and 2.5 mL (½ teaspoon).
Adults and Adolescents 12 Years of Age and Over
The recommended dose of Despej Tablets or Despej Tablets is one 5-mg tablet once daily. The recommended dose of Despej
Oral Solution is 2 teaspoonfuls (5 mg in 10 mL) once daily.
Children 6 to 11 Years of Age
The recommended dose of Despej
Oral Solution is 1 teaspoonful (2.5 mg in 5 mL) once daily. The recommended dose of Despej Tablets is one 2.5-mg tablet once daily.
Children 12 Months to 5 Years of Age
The recommended dose of Despej
Oral Solution is ½ teaspoonful (1.25 mg in 2.5 mL) once daily.
Children 6 to 11 Months of Age
The recommended dose of Despej
Oral Solution is 2 mL (1 mg) once daily.
Adults with Hepatic or Renal Impairment
In adult patients with liver or renal impairment, a starting dose of one 5-mg tablet every other day is recommended based on pharmacokinetic data. Dosing recommendation for children with liver or renal impairment cannot be made due to lack of data.
More about Despej (Despej)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 5 Reviews - Add your own review/rating
- Generic Availability
Consumer resources
- Despej
- Despej syrup
- Despej (Advanced Reading)
Professional resources
- Despej (AHFS Monograph)
- Despej (FDA)
Other formulations
- Despej-D 24 Hour
- Despej-D 12 Hour
- Despej
Related treatment guides
- Allergic Rhinitis
- Urticaria
Despej interactions
See also:
What other drugs will affect Despej?
Inhibitors Of Cytochrome P450 3A4
In controlled clinical studies co-administration of Despej with ketoconazole, erythromycin, or azithromycin resulted in increased plasma concentrations of Despej and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Despej.
Fluoxetine
In controlled clinical studies co-administration of Despej with fluoxetine, a selective serotonin reuptake inhibitor (SSRI), resulted in increased plasma concentrations of Despej and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Despej.
Cimetidine
In controlled clinical studies co-administration of Despej with cimetidine, a histamine H2-receptor antagonist, resulted in increased plasma concentrations of Despej and 3 hydroxydesloratadine, but there were no clinically relevant changes in the safety profile of Despej.
Drug Abuse And Dependence
There is no information to indicate that abuse or dependency occurs with Despej Tablets.
Despej side effects
See also:
What are the possible side effects of Despej?
In clinical trials in a range of indications including allergic rhinitis and chronic idiopathic urticaria, at the recommended dose of 5 mg daily, undesirable effects with Despej tablets were reported in 3 % of patients in excess of those treated with placebo. The most frequent adverse events reported in excess of placebo were fatigue (1.2 %), dry mouth (0.8 %), and headache (0.6 %).
Very rare cases of hypersensitivity reactions (including anaphylaxis and rash) tachycardia, palpitations, psychomotor hyperactivity, seizures, elevations of liver enzymes, hepatitis, and increased bilirubin have been reported during the marketing of Despej.
Despej Syr: In clinical trials in a paediatric population, Despej Syrup was administered to a total of 246 children aged 6 months through 11 years. The overall incidence of adverse events in children 2 through 11 years of age was similar for Despej Syrup and the placebo groups. In infants and toddlers aged 6 to 23 months, the most frequent adverse events reported in excess of placebo were diarrhea (3.7%), fever (2.3%) and insomnia (2.3%).
Despej contraindications
See also:
What is the most important information I should know about Despej?
You should not take this medication if you are allergic to Despej or to loratadine (Claritin).
Before taking Despej, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.
Do not give this medication to a child younger than 2 years old without the advice of a doctor.
Despej disintegrating tablets (Despej) may contain phenylalanine. Talk to your doctor before using this form of Despej if you have phenylketonuria (PKU).
Active ingredient matches for Despej:
Desloratadine in Peru.
List of Despej substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Desora 5 | |
| Despeval (Chile) | |
| Syrup; Oral; Desloratadine 2.5 mg / 5 ml | |
| Tablet; Oral; Desloratadine 5 mg | |
| Despex (Chile) | |
| Syrup; Oral; Desloratadine 2.5 mg / 5 ml (Alcon) | |
| Tablet; Oral; Desloratadine 5 mg (Alcon) | |
| Desrinal (Turkey) | |
| Dest | |
| Dest 5 mg Tablet (Sumages Pharma Pvt. Ltd) | $ 0.03 |
| Desta (Bangladesh) | |
| Destacin (Bangladesh) | |
| Destadin (Brazil) | |
| Destazine (Pakistan) | |
| Destin (Bangladesh) | |
| Destina (Pakistan) | |
| Desybel 2.5mg/5ml (Bulgaria) | |
| Desybel 5mg (Bulgaria) | |
| Dexio (Colombia, Dominican Republic, Guatemala, Honduras) | |
| Dexio 5 (Colombia) | |
| Dexlor | |
| Dexlor 5mg Tablet MD (La Med India) | $ 0.07 |
| DEXLOR-MD | |
| DEXLY (India) | |
| DEXLY Capsule/ Tablet / 5mg / 10 units (Hetero Healthcare Ltd.) | $ 0.24 |
| Dexly 5mg TAB / 10 (Hetero Healthcare Ltd.) | $ 0.24 |
| 5 mg x 10's (Hetero Healthcare Ltd.) | $ 0.24 |
| Dexly 5 mg Tablet (Hetero Healthcare Ltd.) | $ 0.02 |
| DEXLY 5MG TABLET 1 strip / 10 tablets each (Hetero Healthcare Ltd.) | $ 0.33 |
| DEXLY tab 5 mg x 10's (Hetero Healthcare Ltd.) | $ 0.24 |
| Dexly 5mg TAB / 10 (Hetero Healthcare Ltd.) | $ 0.24 |
| Dexly 5mg Tablet (Hetero Healthcare Ltd.) | $ 0.03 |
| DEZLORID | |
| DEZLORID 10 MG TABLET 1 strip / 10 tablets each (Intas Pharmaceuticals Ltd) | $ 0.64 |
| DEZLORID 5 MG TABLET 1 strip / 10 tablets each (Intas Pharmaceuticals Ltd) | $ 0.70 |
| Dezlorid 10mg Tablet (Intas Pharmaceuticals Ltd) | $ 0.06 |
| Dezlorid 5mg Tablet (Intas Pharmaceuticals Ltd) | $ 0.07 |
| Dictrin (Pakistan) | |
| Dihengsai (China) | |
| Dilora (India) | |
| Dilora 5mg TAB / 10 (Invision Medi Sciences) | $ 0.42 |
| 5 mg x 10's (Invision Medi Sciences) | $ 0.42 |
| Dilora 5 mg Tablet (Invision Medi Sciences) | $ 0.04 |
| Dilora 50+500 Tablet (Invision Medi Sciences) | $ 0.02 |
| DILORA tab 5 mg x 10's (Invision Medi Sciences) | $ 0.48 |
| DISITCH | |
| Dislen (Uruguay) | |
| DISLOR (India) | |
| DISLOR tab 5 mg x 10's (Daksh) | $ 0.47 |
| Dometin (Vietnam) | |
| Dometin 5 mg x 1 Blister x 10 Tablet (Nycomed) | |
See 812 substitutes for Despej | |
References
- DailyMed. "DESLORATADINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "Desloratadine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Desloratadine". http://www.drugbank.ca/drugs/DB00967 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Despej are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Despej. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yetConsumer reported age
No survey data has been collected yetConsumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
