What is Pyr-A-Pam?
Pyr-A-Pam belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.
Pyr-A-Pam is used to treat pinworms (enterobiasis; oxyuriasis).
Pyr-A-Pam may also be used for other worm infections as determined by your doctor.
Pyr-A-Pam works by paralyzing the worms. They are then passed in the stool.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Pyr-A-Pam is used in certain patients with the following medical condition:
- Common roundworm infection
- Hookworm infection
- More than one worm infection at a time
For patients taking Pyr-A-Pam for hookworm infection :
- Anemia (iron-poor blood) may occur in patients with hookworm infections. Therefore, your doctor may want you to take iron supplements to help clear up the anemia. If so, it is important to take iron every day while you are being treated for hookworms. Do not miss any doses. Your doctor may also want you to keep taking iron supplements for up to 6 months after you stop taking Pyr-A-Pam. If you have any questions about this, check with your doctor.
Pyr-A-Pam indications
Oral
Single or mixed infections due to susceptible worms
Adult: 10 mg/kg as a single dose.
Child: 10 mg/kg as a single dose.
Oral
Ascariasis
Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr.
Oral
Necatoriasis
Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days.
Oral
Enterobiasis
Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose.
Oral
Trichinosis
Adult: 10 mg/kg daily for 5 days.
How should I use Pyr-A-Pam?
Use Pyr-A-Pam as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Pyr-A-Pam may be taken on an empty stomach or with food, milk, or juice.
- Shake well before using a dose of Pyr-A-Pam.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Wear tight underwear both day and night while taking Pyr-A-Pam.
- Pyr-A-Pam is usually prescribed as a single dose.
- Only one dose of Pyr-A-Pam is required. If you forget to take Pyr-A-Pam, take it as soon as you remember.
Ask your health care provider any questions you may have about how to use Pyr-A-Pam.
Pyr-A-Pam description
Pyr-A-Pam is an antinematodal thiophene
Pyr-A-Pam dosage
Pyr-A-Pam Dosage
Applies to the following strength(s): 144 mg/mL; 180 mg; 50 mg/mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
- Enterobiasis
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Trichostrongylosis
- Moniliformis Infection
Usual Pediatric Dose for:
- Enterobiasis
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Trichostrongylosis
- Moniliformis Infection
Additional dosage information:
- Renal Dose Adjustments
- Liver Dose Adjustments
- Dose Adjustments
- Precautions
- Dialysis
- Other Comments
Usual Adult Dose for Enterobiasis
11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.
Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)
11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.
Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)
11 mg/kg base (maximum 1 g) orally daily for 3 days.
Usual Adult Dose for Ascariasis
11 mg/kg base (maximum 1 g) orally once.
Usual Adult Dose for Trichostrongylosis
11 mg/kg base (maximum 1 g) orally once.
Usual Adult Dose for Moniliformis Infection
11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.
Usual Pediatric Dose for Enterobiasis
>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.
Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)
>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.
Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)
>=2 years: 11 mg/kg base (maximum 1 g) orally daily for 3 days.
Usual Pediatric Dose for Ascariasis
>=2 years: 11 mg/kg base (maximum 1 g) orally once.
Usual Pediatric Dose for Trichostrongylosis
>=2 years: 11 mg/kg base (maximum 1 g) orally once.
Usual Pediatric Dose for Moniliformis Infection
>=2 years: 11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Pyr-A-Pam is contraindicated in patients with hepatic disease.
Dose Adjustments
In the treatment of ascariasis, Pyr-A-Pam may be used only if it has been determined that the worm load will not worsen obstruction.
Precautions
Pyr-A-Pam is contraindicated in patients with hepatic disease.
When one individual in a household has pinworms, the entire household should be treated unless otherwise advised. Pinworm infections are easily transmitted to others in the same household.
Pyr-A-Pam should be used with caution in patients with severe malnutrition or anemia. Supportive therapy is recommended for anemic, dehydrated, or malnourished patients prior to administration of the drug.
Other medications are known to antagonize the anthelmintic effect of Pyr-A-Pam. Patients should be advised to consult with their physician before initiating any drug therapy while receiving Pyr-A-Pam.
Dialysis
Data not available
Other Comments
The dose should be taken as a single oral dose. It may be taken alone or with milk or fruit juice.
Pyr-A-Pam pamoate 2.9 g is approximately equivalent to 1 g of Pyr-A-Pam (base).
More about Pyr-A-Pam
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- En Espanol
- 4 Reviews - Add your own review/rating
Consumer resources
- Pyr-A-Pam chewable tablets
- Pyr-A-Pam pamoate
- Pyr-A-Pam pamoate suspension
- Pyr-A-Pam
- Pyr-A-Pam (Advanced Reading)
- Other brands: Pin-X, Pinworm Medicine, Reese's Pinworm Medicine, Pinworm Caplets, More (2) »
Professional resources
- Pyr-A-Pam Pamoate (AHFS Monograph)
Related treatment guides
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Enterobiasis
- Moniliformis Infection
- More (1) »
Pyr-A-Pam interactions
See also:
What other drugs will affect Pyr-A-Pam?
• Dexamethasone
Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.
• Praziquantel
• Cimetidine
Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12). Albendazole sulfoxide plasma concentrations were unchanged 4 hours after dosing.
• Theophylline
The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of albendazole (400 mg) in 6 healthy subjects.
Pyr-A-Pam side effects
See also:
What are the possible side effects of Pyr-A-Pam?
Applies to Pyr-A-Pam: oral suspension, oral tablet, oral tablet chewable
In addition to its needed effects, some unwanted effects may be caused by Pyr-A-Pam (the active ingredient contained in Pyr-A-Pam). In the event that any of these side effects do occur, they may require medical attention.
Severity: Moderate
If any of the following side effects occur while taking Pyr-A-Pam, check with your doctor or nurse as soon as possible:
Rare
- Skin rash
Minor Side Effects
Some of the side effects that can occur with Pyr-A-Pam may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Less common:
- Abdominal or stomach cramps or pain
- diarrhea
- dizziness
- drowsiness
- headache
- irritability
- loss of appetite
- nausea or vomiting
- trouble in sleeping
Pyr-A-Pam contraindications
See also:
What is the most important information I should know about Pyr-A-Pam?
This medicine is contraindicated in patients with known hypersensitivity to the benzimidazole class of compounds or any components of this medicine.
Active ingredient matches for Pyr-A-Pam:
| Unit description / dosage (Manufacturer) | Price, USD |
| Tablet; Oral; Pyrantel Pamoate 35 mg | |
List of Pyr-A-Pam substitutes (brand and generic names): | |
| Provid (Ireland, United Kingdom) | |
| Pyr-A-Pam II | |
| Tablet; Oral; Pyrantel Pamoate 125 mg | |
| Pyran | |
| Tablet; Oral; Pyrantel Pamoate 35 mg | |
| Tablet; Oral; Pyrantel Pamoate 125 mg | |
| Pyrantel (Austria, Finland, France, Germany, Israel, Luxembourg, New Zealand, Norway, Poland, South Africa, Sweden, Switzerland, United Kingdom, United States) | |
| Suspension; Oral; Pyrantel Pamoate 250 mg / 5 ml | |
| Tablet; Oral; Pyrantel Pamoate 250 mg | |
| Suspension; Oral; Pyrantel 250 mg / 5 ml | |
| Tablet; Oral; Pyrantel 250 mg | |
| Suspension; Oral; Pyrantel Embonate 250 mg / 5 ml | |
| Pyrantel Chewable Tablets | |
| Pyrantel Pamoate Farnam (United States) | |
| Pyrantel Pamoato (Italy) | |
| Pyrantel Paste (Germany) | |
| Pyrantel Polpharma (Georgia, Latvia) | |
| Pyrantel Sine (China) | |
| Pyrantel Vetos-Farma dla kotow For cats (Poland) | |
| Pyrantel Vetos-Farma dla psow For dogs (Poland) | |
| Pyrantelum (Latvia, Poland) | |
| Pyrantelum Medana (Latvia) | |
| Pyrantelum Medana / / höông vò mô 250 mg/5 mL x 1 Bottle 15 mL in duïng cuï ñong coù chia vaïch | |
| Pyrantelum Polpharma (Poland) | |
| Pyrantesan (Poland) | |
| Pyrantin (Sri Lanka, Tunisia) | |
| Pyrantverm (Poland) | |
| Pyrapam (Thailand) | |
| Pyrapam 125 mg x 1, 000's (General Drugs House) | |
| Pyrapam 50 mg/1 mL x 10 mL (General Drugs House) | |
| Pyrapam oral susp 50 mg/mL 10 mL x 1's (General Drugs House) | |
| Pyrapam tab 125 mg 1000's (General Drugs House) | |
| Pyratape (Ireland, United Kingdom) | |
| Pyraverm 250 | |
| Pyrequan | |
| Pyteldon (Thailand) | |
| Pyteldon 125 mg x 100's | |
| Pyteldon 250 mg/5 mL x 10 mL x 12's | |
| Q.T. Ban Tech (United States) | |
| Quantrel (Colombia, Peru, Philippines) | |
| Quantrel 10 mL (Johnson & Johnson) | $ 3.57 |
| Quantrel oral susp 10 mL x 1's (Johnson & Johnson) | $ 3.57 |
| Reese's Pinworm (United States) | |
| Reese's Pinworm Medicine | |
| Reese's Pinworm Medicine Suspension | |
| RFD (United States) | |
| Runcid (Germany) | |
| Sepantel (Finland, France, Netherlands) | |
| Strongid (Finland, France, Ireland, Italy, Netherlands, Portugal, Switzerland, United Kingdom, United States) | |
See 286 substitutes for Pyr-A-Pam | |
References
- PubChem. "PYRANTEL". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Pyrantel". http://www.drugbank.ca/drugs/DB11156 (accessed September 17, 2018).
- MeSH. "Antinematodal Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Pyr-A-Pam are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Pyr-A-Pam. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
