What is Pirantel Pamoato?
Pirantel Pamoato belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.
Pirantel Pamoato is used to treat pinworms (enterobiasis; oxyuriasis).
Pirantel Pamoato may also be used for other worm infections as determined by your doctor.
Pirantel Pamoato works by paralyzing the worms. They are then passed in the stool.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Pirantel Pamoato is used in certain patients with the following medical condition:
- Common roundworm infection
- Hookworm infection
- More than one worm infection at a time
For patients taking Pirantel Pamoato for hookworm infection :
- Anemia (iron-poor blood) may occur in patients with hookworm infections. Therefore, your doctor may want you to take iron supplements to help clear up the anemia. If so, it is important to take iron every day while you are being treated for hookworms. Do not miss any doses. Your doctor may also want you to keep taking iron supplements for up to 6 months after you stop taking Pirantel Pamoato. If you have any questions about this, check with your doctor.
Pirantel Pamoato indications
Oral
Single or mixed infections due to susceptible worms
Adult: 10 mg/kg as a single dose.
Child: 10 mg/kg as a single dose.
Oral
Ascariasis
Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr.
Oral
Necatoriasis
Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days.
Oral
Enterobiasis
Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose.
Oral
Trichinosis
Adult: 10 mg/kg daily for 5 days.
How should I use Pirantel Pamoato?
Use Pirantel Pamoato as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Pirantel Pamoato may be taken on an empty stomach or with food, milk, or juice.
- Shake well before using a dose of Pirantel Pamoato.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Wear tight underwear both day and night while taking Pirantel Pamoato.
- Pirantel Pamoato is usually prescribed as a single dose.
- Only one dose of Pirantel Pamoato is required. If you forget to take Pirantel Pamoato, take it as soon as you remember.
Ask your health care provider any questions you may have about how to use Pirantel Pamoato.
Pirantel Pamoato description
Pirantel Pamoato is an antinematodal thiophene
Pirantel Pamoato dosage
Pirantel Pamoato Dosage
Applies to the following strength(s): 144 mg/mL; 180 mg; 50 mg/mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
- Enterobiasis
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Trichostrongylosis
- Moniliformis Infection
Usual Pediatric Dose for:
- Enterobiasis
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Trichostrongylosis
- Moniliformis Infection
Additional dosage information:
- Renal Dose Adjustments
- Liver Dose Adjustments
- Dose Adjustments
- Precautions
- Dialysis
- Other Comments
Usual Adult Dose for Enterobiasis
11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.
Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)
11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.
Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)
11 mg/kg base (maximum 1 g) orally daily for 3 days.
Usual Adult Dose for Ascariasis
11 mg/kg base (maximum 1 g) orally once.
Usual Adult Dose for Trichostrongylosis
11 mg/kg base (maximum 1 g) orally once.
Usual Adult Dose for Moniliformis Infection
11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.
Usual Pediatric Dose for Enterobiasis
>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.
Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)
>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.
Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)
>=2 years: 11 mg/kg base (maximum 1 g) orally daily for 3 days.
Usual Pediatric Dose for Ascariasis
>=2 years: 11 mg/kg base (maximum 1 g) orally once.
Usual Pediatric Dose for Trichostrongylosis
>=2 years: 11 mg/kg base (maximum 1 g) orally once.
Usual Pediatric Dose for Moniliformis Infection
>=2 years: 11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Pirantel Pamoato is contraindicated in patients with hepatic disease.
Dose Adjustments
In the treatment of ascariasis, Pirantel Pamoato may be used only if it has been determined that the worm load will not worsen obstruction.
Precautions
Pirantel Pamoato is contraindicated in patients with hepatic disease.
When one individual in a household has pinworms, the entire household should be treated unless otherwise advised. Pinworm infections are easily transmitted to others in the same household.
Pirantel Pamoato should be used with caution in patients with severe malnutrition or anemia. Supportive therapy is recommended for anemic, dehydrated, or malnourished patients prior to administration of the drug.
Other medications are known to antagonize the anthelmintic effect of Pirantel Pamoato. Patients should be advised to consult with their physician before initiating any drug therapy while receiving Pirantel Pamoato.
Dialysis
Data not available
Other Comments
The dose should be taken as a single oral dose. It may be taken alone or with milk or fruit juice.
Pirantel Pamoato pamoate 2.9 g is approximately equivalent to 1 g of Pirantel Pamoato (base).
More about Pirantel Pamoato
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- En Espanol
- 4 Reviews - Add your own review/rating
Consumer resources
- Pirantel Pamoato chewable tablets
- Pirantel Pamoato pamoate
- Pirantel Pamoato pamoate suspension
- Pirantel Pamoato
- Pirantel Pamoato (Advanced Reading)
- Other brands: Pin-X, Pinworm Medicine, Reese's Pinworm Medicine, Pinworm Caplets, More (2) »
Professional resources
- Pirantel Pamoato Pamoate (AHFS Monograph)
Related treatment guides
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Enterobiasis
- Moniliformis Infection
- More (1) »
Pirantel Pamoato interactions
See also:
What other drugs will affect Pirantel Pamoato?
• Dexamethasone
Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.
• Praziquantel
• Cimetidine
Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12). Albendazole sulfoxide plasma concentrations were unchanged 4 hours after dosing.
• Theophylline
The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of albendazole (400 mg) in 6 healthy subjects.
Pirantel Pamoato side effects
See also:
What are the possible side effects of Pirantel Pamoato?
Applies to Pirantel Pamoato: oral suspension, oral tablet, oral tablet chewable
In addition to its needed effects, some unwanted effects may be caused by Pirantel Pamoato (the active ingredient contained in Pirantel Pamoato). In the event that any of these side effects do occur, they may require medical attention.
Severity: Moderate
If any of the following side effects occur while taking Pirantel Pamoato, check with your doctor or nurse as soon as possible:
Rare
- Skin rash
Minor Side Effects
Some of the side effects that can occur with Pirantel Pamoato may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Less common:
- Abdominal or stomach cramps or pain
- diarrhea
- dizziness
- drowsiness
- headache
- irritability
- loss of appetite
- nausea or vomiting
- trouble in sleeping
Pirantel Pamoato contraindications
See also:
What is the most important information I should know about Pirantel Pamoato?
This medicine is contraindicated in patients with known hypersensitivity to the benzimidazole class of compounds or any components of this medicine.
Active ingredient matches for Pirantel Pamoato:
Pyrantel in Peru.
List of Pirantel Pamoato substitutes (brand and generic names) | Sort by popularity |
Unit description / dosage (Manufacturer) | Price, USD |
Pirantel Pamoato Ophalac (Colombia) | |
Pirantelina (Paraguay) | |
Pirantelis (Lithuania) | |
Pirantelis Medana (Lithuania) | |
Pirantrim (Mexico) | |
Piraska (Indonesia) | |
Pirel (Colombia) | |
Pleosan (Venezuela) | |
Premelange 25 / 2 Porcs Medicamente Pro-Ban | |
Drug Premix; Oral; Pyrantel Tartrate 8.48 g / kg | |
Pro-Banminth | |
Drug Premix; Oral; Pyrantel Tartrate 106 g / kg | |
Pro-Banminth Swine Premix | |
Drug Premix; Oral; Pyrantel Tartrate 106 g / kg | |
Provid (Ireland, United Kingdom) | |
Pyr-A-Pam | |
Tablet; Oral; Pyrantel Pamoate 35 mg | |
Pyr-A-Pam II | |
Tablet; Oral; Pyrantel Pamoate 125 mg | |
Pyran | |
Tablet; Oral; Pyrantel Pamoate 35 mg | |
Tablet; Oral; Pyrantel Pamoate 125 mg | |
Pyrantel (Austria, Finland, France, Germany, Israel, Luxembourg, New Zealand, Norway, Poland, South Africa, Sweden, Switzerland, United Kingdom, United States) | |
Suspension; Oral; Pyrantel Pamoate 250 mg / 5 ml | |
Tablet; Oral; Pyrantel Pamoate 250 mg | |
Suspension; Oral; Pyrantel 250 mg / 5 ml | |
Tablet; Oral; Pyrantel 250 mg | |
Suspension; Oral; Pyrantel Embonate 250 mg / 5 ml | |
Pyrantel Chewable Tablets | |
Pyrantel Pamoate Farnam (United States) | |
Pyrantel Pamoato (Italy) | |
Pyrantel Paste (Germany) | |
Pyrantel Polpharma (Georgia, Latvia) | |
Pyrantel Sine (China) | |
Pyrantel Vetos-Farma dla kotow For cats (Poland) | |
Pyrantel Vetos-Farma dla psow For dogs (Poland) | |
Pyrantelum (Latvia, Poland) | |
Pyrantelum Medana (Latvia) | |
Pyrantelum Medana / / höông vò mô 250 mg/5 mL x 1 Bottle 15 mL in duïng cuï ñong coù chia vaïch | |
Pyrantelum Polpharma (Poland) | |
Pyrantesan (Poland) | |
Pyrantin (Sri Lanka, Tunisia) | |
Pyrantverm (Poland) | |
Pyrapam (Thailand) | |
Pyrapam 125 mg x 1, 000's (General Drugs House) | |
Pyrapam 50 mg/1 mL x 10 mL (General Drugs House) | |
Pyrapam oral susp 50 mg/mL 10 mL x 1's (General Drugs House) | |
Pyrapam tab 125 mg 1000's (General Drugs House) | |
Pyratape (Ireland, United Kingdom) | |
Pyraverm 250 | |
Pyrequan | |
See 286 substitutes for Pirantel Pamoato |
References
- PubChem. "PYRANTEL". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Pyrantel". http://www.drugbank.ca/drugs/DB11156 (accessed September 17, 2018).
- MeSH. "Antinematodal Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Pirantel Pamoato are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Pirantel Pamoato. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology